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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A8JUY3_DROME (A8JUY3)

Summary

This is the summary of UniProt entry A8JUY3_DROME (A8JUY3).

Description: DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279}
Source organism: Drosophila melanogaster (Fruit fly) (NCBI taxonomy ID 7227)
Length: 1383 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam RNA_pol_Rpb1_1 12 355
disorder n/a 189 192
disorder n/a 198 208
disorder n/a 272 273
disorder n/a 338 339
Pfam RNA_pol_Rpb1_2 357 524
disorder n/a 400 407
disorder n/a 411 415
disorder n/a 417 419
disorder n/a 503 504
disorder n/a 506 507
Pfam RNA_pol_Rpb1_3 527 701
low_complexity n/a 581 593
disorder n/a 615 617
Pfam RNA_pol_Rpb1_4 726 832
Pfam RNA_pol_Rpb1_5 839 1309
disorder n/a 920 926
disorder n/a 928 944
disorder n/a 1029 1030

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A8JUY3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPKEQFRASA LNKKISHVQF GISGADEIQQ EALVRIISKN LYQAQRQPVP
50
51
YGVLDRRMGI STKDAMCETC GQGLNECIGH FGYLDLALPV FHIGHFRSTI
100
101
NILQMICKVC AHVMLKPEDR QLYEKKLHNP NFSYLGKKAL HVQMLAKAKK
150
151
VTKCPHCGSP NGGVKKGPGL LKILHDPYKG RKMDSLFTSN MNEMLRSTQT
200
201
NRDLNSTLGN YSTAEELTPL MVLDLFEQIP QRDVALLGMC SHDAHPKHLI
250
251
VTRVFVPPAC IRPSVLSEVK AGTTEDDLTM KQSEILLIND VIQRHMATGG
300
301
KIELIHEDWD FLQLHVALYF HSEISGIPIN MAPKKTTRGI VQRLKGKQGR
350
351
FRCNLSGKRV DFSGRTVISP DPNLMINQVG VPVRVAKILT YPERVNPANI
400
401
RHMRELVRNG PSMHPGANYV QQRGSSFKKY LAYGNREKVA QELKCGDVVE
450
451
RHLRDGDIVL FNRQPSLHKM SIMCHRAKVQ PQRTFRFNEC ACTPYNADFD
500
501
GDEMNLHLPQ TEEARAEALI LMGNQSNLVT PKNGEILIAA TQDFITGGYL
550
551
LTQKEVFLTK EEAMQLAACF LANEDSTMHI KLPPPALLKP RRLWTGKQMF
600
601
SLLMRPNDDS QVRLNMVNKG RNYTRNKDLC SNDSWIHIRN SELMCGVMDK
650
651
ATMGSGTKQC IFYLLLRDFG ESHATKAMWR LARIASYFLQ NRGFSFGISD
700
701
VTPSKKLLQH KELLLNNGYA KCNEYIELLK AGTLQCQPGC TPEETLESVM
750
751
LRELSAIREQ AAKTCFAELH PTNSALIMAL SGSKGSNINI SQMIACVGQQ
800
801
AISGKRVPNG FENRALPHFE RHSAIPAARG FVQNSFYSGL TPTEFFFHTM
850
851
AGREGLVDTA VKTAETGYLQ RRLVKCLEDL VVHYDGTVRN AVNEMVDTIY
900
901
GGDGLDPVSM ETRNKPVDLV HQYDNLRAQH PQGKDRPLNA EEMSEALETL
950
951
LRTPEFAEAR DDFKLDVRNH INTVSKRIGQ LQKRYEKCID LCHQIECLTT
1000
1001
EQLLQFVRRI NDRYNRAVTE PGTAVGAIAA QSIGEPGTQM TLKTFHFAGV
1050
1051
ASMNITQGVP RIVEIINATK TISTPIITAE LENCHSMEFA RQVKARIEKT
1100
1101
TLAELSSYVE VVCGPYSCYL AIGVDMARIK LLGLHIDLDT IVFSILKSRM
1150
1151
RVKPTQVEVV ASQSRIVVRV EATRTSTINA ELARLALSLQ NVVVAGLPNI
1200
1201
NRAVIAVDDA RQPPTYKLCI EGYGLRDVIA TYGVVGKRTR SNNICEIYQT
1250
1251
LGIEAARTII MSEITEVMEG HGMSVDWRHI MLLASQMTAR GEVLGITRHG
1300
1301
LAKMRESVFN LASFEKTADH LFDAAYYGQT DAINGVSERI ILGMPACIGT
1350
1351
GIFKLLQQHE DKQVPPIEPT ICSSLNLLPS KTT                  
1383
 

Show the unformatted sequence.

Checksums:
CRC64:3889FBEFA9A750B8
MD5:0015ba6de5f9bc7028868e4a0ed776fd

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;