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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: B0S754_DANRE (B0S754)

Summary

This is the summary of UniProt entry B0S754_DANRE (B0S754).

Description: Activating signal cointegrator 1 complex subunit 3 {ECO:0000256|ARBA:ARBA00014590}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 2134 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 24 28
disorder n/a 31 32
disorder n/a 39 46
disorder n/a 50 78
low_complexity n/a 65 78
disorder n/a 144 145
disorder n/a 147 148
disorder n/a 151 161
disorder n/a 183 184
disorder n/a 186 245
low_complexity n/a 206 215
low_complexity n/a 222 237
disorder n/a 248 253
Pfam Helicase_PWI 253 362
disorder n/a 343 346
low_complexity n/a 366 385
disorder n/a 370 377
disorder n/a 381 389
disorder n/a 392 393
disorder n/a 443 446
Pfam DEAD 479 659
low_complexity n/a 608 620
Pfam Helicase_C 700 857
low_complexity n/a 873 884
Pfam Sec63 978 1282
low_complexity n/a 1028 1039
Pfam DEAD 1325 1498
Pfam Sec63 1808 2119
low_complexity n/a 1814 1825
disorder n/a 1867 1868
low_complexity n/a 2031 2043
disorder n/a 2120 2134

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession B0S754. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MADVTARSLQ YEYKANSNLV LQADRSLIDR TRRDEPTGEV LSLVGKLEGT
50
51
KMGDRSQRTK PQMLEERRAK RRKRDEDRHD INKMKGFTLL SEGIDEMVGI
100
101
VYKPKTKETR ETYEILLSFI QAALGDQPRD ILCGAADEVL AVLKNDKMRD
150
151
KERRREVEQL LGPTDDTRYH VLVNLGKKIS DYGGDKELQN MDDNIDETYG
200
201
VNVQFESDEE EGDEDQYGEV RDEGSDDSEG EEADESSTLT ANLGNTGDVM
250
251
MTKKKDLHPR DIDAFWLQRQ LSRFYNDAIV SQKKADEVLE ILKTASDDRE
300
301
CENQLVLLLG FNTFDFIKVL RQHRRMILYC TMLASAQSEA EKEKIINKME
350
351
ADQDLSKVLY QLQETEKEDI IREERSRRER MRKSRVDDLE SMDIDHGESV
400
401
SSRQLLDLED LTFTQGSHFM ANKRCQLPDG SFRKQRKGYE EVHVPALKPK
450
451
PFGDEETLVG IEKLPKYAQA GFEGFKSLNR IQSKLFKTTM ETDENLLVCA
500
501
PTGAGKTNVA LMAMLREIGK HINMDGTINV ADFKIIYIAP MRSLVQEMVG
550
551
SFGKRLASYG IIVSELTGDH QLCKEEINAT QIIVCTPEKW DIITRKGGER
600
601
TYTQLVRLII IDEIHLLHDD RGPVLESLIA RTIRNVELTQ EDVRLIGLSA
650
651
TLPNYEDVAT CLRVDPSKGL FYFDNSFRPV PLEQTYVGIT EKKAIKRFQI
700
701
MNEIVYEKIM EHAGKNQVLV FVHSRKETGK TARAIRDMCL EKDTLGLFLR
750
751
EGSASTEVLR TEAEQCKNLE LKDLLPYGFA IHHAGMTRVD RTLVEDLFAD
800
801
RHIQVLVSTA TLAWGVNLPA HTVIIKGTQV YSPEKGRWTE LGALDILQML
850
851
GRAGRPQYDS KGEGILITSH GELQYYLSLL NQQLPIESQM VGKLADMLNA
900
901
EIVLGNVQNA KDAVNWLGYT YLYVRMLRNP TLYGVSHDDR SIDPLLERRR
950
951
MDLVHTAATV LEKNNLVKYD KRSGSFQVTD LGRIASHFYI THESIMTYNQ
1000
1001
LLKPTLSEIE LFRVFSLSSE FRNITVREEE KLELQKLLER VPIPVKESIE
1050
1051
EPSAKINVLL QAYISQLKLE GFALMADMVY VTQSAGRLMR AIFEIVLSRG
1100
1101
WAQLTDKTLN LCKMIDKRMW QSMSPLRQFR KLPEEVIKKI EKKNFPFERL
1150
1151
YDLNHNEIGE LIRMPKMGKT IHKYVHQFPK LDLAVHLQPI TRSTLKVELT
1200
1201
ITPDFQWDDK IHGSSEAFWI LVEDVDSEVV LHHEYFLLKA KYAQDEHLVT
1250
1251
FFVPVFEPLP PQYFIRIASD RWLSCETQLP VSFRHLILPE KYPPPTELLD
1300
1301
LQPLPVSALR NGAFESLYQN FPFFNPIQTQ VFNAVYNSDD NVFVGAPTGS
1350
1351
GKTICAEFAI LRMLLHNAEG RCVYITPMEA LAEQVFLDWH QKFQENLNKK
1400
1401
VVLLTGETST DLKLLGKGDI IVSTPDKWDI LSRRWKQRKN VQNVSLFIID
1450
1451
EVHLIGGDNG PVLEVICSRM RYISSQIERP IRIVALSSSL SNAKDVAHWL
1500
1501
GCSTTATFNF HPNVRPVPLE LHIQGFNVSH TQTRLLSMAK PVYHAIMKHS
1550
1551
PSKPVLVFVP SRRQTRLTAI DILTFCAADV VPQRFLHSTE KDLVPFMENL
1600
1601
SDVTLKETLS NGVGYLHEGL SPTERRIVEH LFTSGAIQVV VASRSLCWGT
1650
1651
NISAHLVIVM DTQYYNGKIH AYVDYPIYDV LQMVGKANRP LQDDEGRCVI
1700
1701
MCQGSKKDFF KKFLYEPLPV ESHLDHCLHD HFNAEIVTKT VENKQDAVDY
1750
1751
LTWTFLYRRM TQNPNYYNLQ GMSHRHLSDH LSELVENTLQ DLEQSKCISI
1800
1801
EDEMDVAPLN LGMIAAYYYI NYTTIELFSM SLNAKTKVRG LIEIISNAAE
1850
1851
YKNIPIRHHE DTLLRQLAQK VPHKLNNPKF NDPHVKTNLL LQAHLSRMQL
1900
1901
SAELQSDTEE ILSKAVRLIQ ACVDVLSSNG WLSPALAAME LAQMVTQAMW
1950
1951
SKDSYLRQLP HFTSELIKRC TDKGVESIFD IMEMEDEDRT GLLQLSDVQV
2000
2001
ADVARFCNRY PNIELSYEVV DKDDIKSGSP VVVQVQLERE EEVTGPVIAP
2050
2051
LFPQKREEGW WVVIGDPKSN SLISIKRLTL QQKAKVKLDF VAPVVGVHNY
2100
2101
TLYFMSDAYM GCDQEYKFST EVKEADSEGD SDSD                 
2134
 

Show the unformatted sequence.

Checksums:
CRC64:3A87928F0CB7E1C9
MD5:ba929640088400542fb4b06d1582695c

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;