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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PDE1_DROME (B7YZV4)

Summary

This is the summary of UniProt entry PDE1_DROME (B7YZV4).

Description: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1 {ECO:0000305}
Source organism: Drosophila melanogaster (Fruit fly) (NCBI taxonomy ID 7227)
Length: 834 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 16
disorder n/a 23 25
disorder n/a 29 31
disorder n/a 51 101
disorder n/a 104 119
disorder n/a 143 339
low_complexity n/a 157 165
low_complexity n/a 175 188
low_complexity n/a 207 222
low_complexity n/a 245 258
low_complexity n/a 255 283
low_complexity n/a 279 301
Pfam PDEase_I_N 323 383
disorder n/a 342 346
disorder n/a 354 364
Pfam PDEase_I 468 694
disorder n/a 702 710
disorder n/a 714 750
disorder n/a 783 834
low_complexity n/a 787 817
low_complexity n/a 823 834

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession B7YZV4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MQPSSPNATN YLADNIQISS ANLSQTEMVV GRDSADYTAM HSINVGVGNS
50
51
FLRGDTDIPQ ESGHSFETPS NMSFTAGQWD TESLPPVDTP DALNKAAGRI
100
101
RSLLRRMDHE TVAYEDMQRN LHYAARVLEA VFIDESREGC NGNCKNLNCS
150
151
RHSHGRDDQQ QDNNNSNRSC SLQEASPGGA GAGVTPGADN QDSIESRTKG
200
201
VSQAPQTHSG PTGPPSNTSS ETIAQPAPKL QPALETVRES VMEESPSKDP
250
251
GDKGPPPPAS TSTLTSQTTT SSSATAEPSA KAAESQAGSA GSSGSCSNPA
300
301
AVHRQRRLRT PTWARSMSTN KTRLADEDDE LSEVQPDAVP PEVREWLAST
350
351
FTRQMATSRR KSDEKPKFRS VAHAIRAGIF VDRMYRRVSS SALTAFPPDV
400
401
VRLLKNLDDW TFDVFALTEA ASGQVVKYVA YELFNRYGSI HKFKIAPGIL
450
451
EAFLHRVEEG YCRYRNPYHN NLHAVDVMQT IHYCLCNTGL MNWLTDLEIF
500
501
ASLLAALLHD YEHTGTTNNF HVMSGSETAL LYNDRAVLEN HHASASFRLL
550
551
REDEYNILSH LSREEFRELR GLVIEMVLGT DMTNHFQQMK AMRQLLTLQE
600
601
ATIDKQKVLS LVLHCCDISH PAKQWGVHHR WTMLLLEEFF RQGDLEKELG
650
651
LPFSPLCDRN NTLVAESQIC FIDFIVEPSM GVMSDMLELI LAPIAPMNKS
700
701
KPATLVEHET TANSTTNSAI VIPNSGITPS MDKPRDHRTE AKTTAAECLA
750
751
RKSVTGTTAS KFNIPKPWLT CLVENKRIWK EQAVKDAEAR ALATAAEEAA
800
801
AAAAAEAEES KPETETADGE QSEPAAEPAD GAAA                 
834
 

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Checksums:
CRC64:D027A9481010C665
MD5:67e1ec31b8a0d05eceda82f244228061

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;