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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: B7Z001_DROME (B7Z001)

Summary

This is the summary of UniProt entry B7Z001_DROME (B7Z001).

Description: 3-oxoacyl-[acyl-carrier-protein] reductase {ECO:0000256|ARBA:ARBA00018576}
Source organism: Drosophila melanogaster (Fruit fly) (NCBI taxonomy ID 7227)
Length: 2540 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 139
low_complexity n/a 37 61
low_complexity n/a 73 85
Pfam ketoacyl-synt 139 379
disorder n/a 142 149
disorder n/a 162 166
Pfam Ketoacyl-synt_C 383 500
disorder n/a 464 466
Pfam KAsynt_C_assoc 502 611
disorder n/a 546 547
disorder n/a 620 621
Pfam Acyl_transf_1 633 950
Pfam PS-DH 984 1235
disorder n/a 1100 1101
disorder n/a 1110 1111
disorder n/a 1237 1243
disorder n/a 1249 1252
disorder n/a 1266 1267
low_complexity n/a 1457 1470
Pfam ADH_zinc_N_2 1747 1883
Pfam KR 1914 2094
low_complexity n/a 1918 1929
disorder n/a 2139 2140
Pfam PP-binding 2152 2217
low_complexity n/a 2225 2234
disorder n/a 2238 2249
disorder n/a 2252 2253
Pfam Thioesterase 2285 2538

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession B7Z001. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPLQLNLLQA VDQPHPVAFK PNNCSTHQPQ HSPSTQNNGK SARANRRRRR
50
51
RRNKQQQNSQ QPDAFRDTDA QLTPSTSSST PHSAPNDRQD HLNSQFNPES
100
101
INMPARFAEE VITAEPAQRA APQLDLGGGH YVPRQQHLND EIAITGFSGR
150
151
LPESSTIEEF KQNLFDGVDM VNDDPRRWER GLYGLPDRIG KLKDSDLENF
200
201
DQQFFGVHQK QAECMDPLLR MLLELTHEAI IDAGLNPSDL RGSRTGVYIG
250
251
VSNSETEQHW CSDADRVNGY GLTGCARAMF ANRISFTFDF KGPSYSIDTA
300
301
CSSSLYALEQ AFSDMREGKV DNALVAGAGL ILKPTMSLQF KRLNMLSPDG
350
351
SCKAFDESGN GYVRSDGCVV LLLQRTSAAR RVYASILNVR TNTDGFKEQG
400
401
ITYPIGKMQN RLIRETYEEI GLNPADVVYV EAHGTGTKVG DPQEVNSITD
450
451
FFCKDRTTPL LIGSVKSNMG HSEPASGVCS VAKILIAMEE GVIPGNLHYN
500
501
KPNPDLYGLV DGRLKVVDRN LPWNGGIIGL NSFGFGGANA HVILKSNPKP
550
551
KALTPKDGAL KVVLASGRTF EAVEQLLESA STNADDDEYL QLINEIHSKA
600
601
IPNHFFRGYG VVSSKGTHQR EVIESNDDKR PIWYIYSGMG SQWASMAKDL
650
651
MKIEAFAKTI QRCADVLKPE GVDLIDVLTR STDKSFENIL NSFISIAAMQ
700
701
VALTDLLSSL GIHPDGIVGH SVGELGCAYA DGCFTPEQTV LAAYWRGKSI
750
751
LDTQLAKGKM AAVGLSWEDA HSRVPSDCFP VCHNSEDNCT ISGPEASIEA
800
801
LVAKLNAEGV FAKAVNSSGY AFHSKYIAEA GPKLRKSLEK IIPNAKNRTA
850
851
RWISTSIPES AWNTPVAKQS SAAYHVNNLL SPVLFHEALQ HVPKNAISVE
900
901
IAPHGLLQAI LKRALGPDAT NLSLVKRGHE NNVEFFLTNV GKLFAAGAQP
950
951
QVLTLVRPIS YPVGRGTPML NSKVGWDHTQ KWLVAKFGKE TSSGETIVEV
1000
1001
DLSKEDDAFL AGHTIDGRIL FPATGYMTLA WQTFAKMQGS EFHKTPVVME
1050
1051
NLVFHRATIL NKNAVVKFGI NFFDGTGAFE ICESGSLAVS GKITIPESID
1100
1101
NEELPLEEQT PSAVAKELGT NDVYKELRLR GYDYGGIFRG IVRSDTVAST
1150
1151
GKLQWVDNWI SFMDTMLQFS ILSKNLRELY LPTRIERAVI NPAKHFELLS
1200
1201
ALTKEEQVET GLPVQWYSDI NVIKSAGVEL RGLKANLAQR RPGTQAPPTL
1250
1251
ERYQFVPNIN TTDLNENSEK ARLHALDVAI QVIIENSSGA VKLKGVELAN
1300
1301
GRNPDVLVAN RLLQIIEGEP VLTGDVAVVT SNNNEETITA ALGDSGVRVV
1350
1351
SKDVLKEPVE QNCHFVFGID VLSRPDTKTL ENSIASIREN GFLILEETLP
1400
1401
TYTKTGRALL TKFGFVAVQE QSLGATRVLV LARKAVDLKT RKSVVVVATE
1450
1451
QNFNWVDDLK AALATAATEE QYVYVVCQGE ELFGAVGLMT CIKNENGGKL
1500
1501
ARLVFVQDAK AEKFSLTSTL YRQQLEKDLI SNVLKNGAWG TFRHLKLETQ
1550
1551
QATLQVEHAY VNALVKGDLA SLKWIEAAQA DTAATVDKNL ETCTVYYAPI
1600
1601
NFRDVMLTSG KLAADALPGD LAEQDCVLGL EFAGRDTQGR RVMAMVPAKS
1650
1651
LATTCVASKR MMWQIPEKWT MEEASTVPCV YSTVYYALVV RGQMKKGEKI
1700
1701
LIHAGSGGVG QAAISVALAH GLTVFTTVGS KEKREFLLKR FPKLQERNIG
1750
1751
NSRDTSFEQL VLRETKGRGV DLVLNSLSEE KLQASIRCLG LNGRFLEIGK
1800
1801
FDLSNNSPLG MSVFLKNTSF HGILLDSVME GEEEMQNQVV SLVAEGIKTG
1850
1851
AVVPLPTSVF NDQQVEQAFR FMASGKHIGK VVIKVRDEEA GKKALQPKPR
1900
1901
LINAIPRTYM HPEKSYILVG GLGGFGLELT NWLVTRGARY IVLTSRSGVK
1950
1951
TGYQGLMIRR WQERGVKVVI DTSDVTTAAG AKKLLENSNK LALVGGIFNL
2000
2001
AAVLRDALIE DQTAKDFKTV ADPKVTATKY LDQFSRDICT ELDYFICFSS
2050
2051
VSCGRGNIGQ TNYGLANSAM ERICEQRQVS GFPGTAIQWG AIGDTGLVLE
2100
2101
NLGDNDTVIG GTLPQRMPSC LQTIDLFLQQ PHPVVASMVV AEKRKSDQSA
2150
2151
GVSLIATIAN ILGLRDTKNI QDGASLADLG MDSLMSAEIK QTLERNFDIV
2200
2201
LSAQEIRQLT FGALKAMDGG ADVKPAAAAP AAAAGVPEAN ITSGGSSRTA
2250
2251
SPMGDGTQVV FTTSLIPTEA IVQLDTKAPA NSKQSPIFFI SPIEGFASAL
2300
2301
EPLAKRLEVP AYGLQYTEAV PSDSLESAAK FFIKQLRTVQ PKGPYKLAGY
2350
2351
SFGCLLTYVM AGILEETNEV ANVIMLDGAP SYVNWYTSSF KQRYTDGTNA
2400
2401
DNDNQSYGLA YFGIVLANID YKALVRLLIV IPTWEEKLER FAELMSNEIT
2450
2451
QPVETIKKSA TLFYKKLELA DGYQPTLKLK TNVTLVKPTD NSAKLDEDYR
2500
2501
LKEVCTKPVE VHTVEGNHRT FLIEDQSLKT IQSILKRLFN           
2540
 

Show the unformatted sequence.

Checksums:
CRC64:C9CFC916C679637D
MD5:7fd78d970e1b548cb2f466b9aae9477b

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;