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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: D3ZCM7_RAT (D3ZCM7)

Summary

This is the summary of UniProt entry D3ZCM7_RAT (D3ZCM7).

Description: TLE family member 1, transcriptional corepressor {ECO:0000313|Ensembl:ENSRNOP00000055692}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 770 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 10
disorder n/a 12 17
Pfam TLE_N 18 133
coiled_coil n/a 26 53
low_complexity n/a 98 114
disorder n/a 106 110
disorder n/a 126 167
low_complexity n/a 145 161
low_complexity n/a 158 173
disorder n/a 173 361
low_complexity n/a 230 245
low_complexity n/a 255 266
low_complexity n/a 281 296
disorder n/a 363 379
disorder n/a 381 391
low_complexity n/a 401 412
disorder n/a 422 427
disorder n/a 429 435
disorder n/a 461 466
disorder n/a 472 474
Pfam WD40 568 602
Pfam WD40 606 644

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession D3ZCM7. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MFPQSRHPTP HQAAGQPFKF TIPESLDRIK EEFQFLQAQY HSLKLECEKL
50
51
ASEKTEMQRH YVMYYEMSYG LNIEMHKQTE IAKRLNTICA QVIPFLSQEH
100
101
QQQVAQAVER AKQVTMAELN AIIGQQQLQA QHLSHGHGPP VPLTPHPSGL
150
151
QPPGIPPLGG SASLLALSSA LSGQSHLAIK DDKKHHDAER HRDREPGTSN
200
201
SLLVPDSLRG TDKRRNGPEF SSDIKKRKVD DKDNYDSDGD KSDDNLVVDV
250
251
SNEDPSSPHA SPTHSPRENG IDKNRLLKKD ASGSPASTAS SGSSSSLKSK
300
301
EVNLHEKANT PVLKSSTPTP RSDMPTPGTS ATPGLRPGLG KPPAMEPLVN
350
351
QAAAGLRTPL AVPGPYPAPF GMVPHAGMNG ELTSPGAAYA GLHSMSPQMS
400
401
AAAAAAAAAV VAYGRSPMVG FDPPPHMRVP SIPPNLAGIP GGKPAYSFHV
450
451
TADGQMQPVP FPPDALIGPG IPRHARQINT LNHGEVVCAV TISNPTRHVY
500
501
TGGKGCVKVW DISHPGNKSP VSQLDCLNRD NYIRSCKLLP DGCTLIVGGE
550
551
ASTLSIWDLA APTPRIKAEL TSSAPACYAL AISPDSKVCF SCCSDGNIAV
600
601
WDLHNQTLVR QFQGHTDGAS CIDISNDGTK LWTGGLDNTV RSWDLREGRQ
650
651
LQQHDFTSQI FSLGYCPTGE WLAVGMESSN VEVLHVNKPD KYQLHLHESC
700
701
VLSLKFAYCG KWFVSTGKDN LLNAWRTPYG ASIFQSKESS SVLSCDISVD
750
751
DKYIVTGSGD KKATVYEVIY                                 
770
 

Show the unformatted sequence.

Checksums:
CRC64:7FFD734EF3F2AE36
MD5:da69630b683e61182b003a1237385ca7

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;