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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: D3ZKG1_RAT (D3ZKG1)

Summary

This is the summary of UniProt entry D3ZKG1_RAT (D3ZKG1).

Description: Methylmalonyl-CoA isomerase {ECO:0000256|ARBA:ARBA00019196}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 833 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 30 33
disorder n/a 36 38
disorder n/a 41 51
low_complexity n/a 47 62
Pfam MM_CoA_mutase 145 657
low_complexity n/a 595 605
disorder n/a 667 668
Pfam B12-binding 698 816
disorder n/a 701 704
low_complexity n/a 740 752

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession D3ZKG1. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKKPDTLVEK GWTKGVCLIR HQTRARNGGI GLAEPRAELA TPPELTGSGA
50
51
PAASASGSRA LGFDLRGRPP TLFVLIFVWE YSCFTMLRAK NQLFLLSPHY
100
101
LKQLKDASSY RWKRLLHQQQ PLHPEWAVLA KKQLKGKNPE DLIWHTPEGI
150
151
SIKPLYSRAD TMDLPEELPG VKPFTRGPYP TMYTYRPWTI RQYAGFSTVE
200
201
ESNKFYKDNI KAGQQGLSVA FDLATHRGYD SDNPRVRGDV GMAGVAIDTV
250
251
EDTKILFDGI PLEKMSVSMT MNGAVIPVLA TFIVTGEEQG VPKEKLTGTI
300
301
QNDILKEFMV RNTYIFPPEP SMKIIADIFQ YTAQHMPKFN SISISGYHMQ
350
351
EAGADAILEL AYTIADGLEY CRTGLQAGLT IDEFAPRLSF FWGIGMNFYM
400
401
EIAKMRAGRR LWAHLIEKMF QPKNSKSLLL RAHCQTSGWS LTEQDPYNNI
450
451
VRTAIEAMAA VFGGTQSLHT NSFDEALGLP TVKSARIARN TQIIIQEESG
500
501
IPKVADPWGG SYMMESLTND VYEAALKLIY EVEEMGGMAK AVAEGIPKLR
550
551
IEECAARRQA RIDSGSEVIV GVNKYQLEKE DSVEVLAIDN TSVRKKQIEK
600
601
LKKIKSSRDQ ALAERSLNAL TQCAASGDGN ILALAVDAAR ARCTVGEITD
650
651
ALKKVFGEHK ANDRMVSGAY RQEFGESKEI TSAIKRVNKF MEREGRRPRL
700
701
LVAKMGQDGH DRGAKVIATG FADLGFDVDI GPLFQTPREV AQQAVDADVH
750
751
AVGVSTLAAG HKTLVPELIK ELSALGRPDI LVMCGGVIPP QDYEFLYEVG
800
801
VSNVFGPGTR IPKAAVQVLD DIEKSLAEKQ QSV                  
833
 

Show the unformatted sequence.

Checksums:
CRC64:5C656E1FFF99F727
MD5:27d969cf60e76208791339b9a8ffb0f4

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;