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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: D3ZV21_RAT (D3ZV21)

Summary

This is the summary of UniProt entry D3ZV21_RAT (D3ZV21).

Description: Forkhead box O6 {ECO:0000313|Ensembl:ENSRNOP00000051244}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 628 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 2 79
low_complexity n/a 33 49
low_complexity n/a 55 69
Pfam Forkhead 88 176
disorder n/a 132 133
disorder n/a 135 139
disorder n/a 148 152
disorder n/a 162 186
disorder n/a 200 233
low_complexity n/a 210 228
low_complexity n/a 225 239
disorder n/a 241 244
disorder n/a 253 275
low_complexity n/a 255 272
low_complexity n/a 270 290
disorder n/a 277 279
disorder n/a 288 292
disorder n/a 296 298
disorder n/a 301 306
low_complexity n/a 301 319
disorder n/a 309 310
disorder n/a 315 317
disorder n/a 321 324
disorder n/a 326 330
low_complexity n/a 342 364
Pfam FOXO_KIX_bdg 353 405
disorder n/a 360 369
disorder n/a 371 380
low_complexity n/a 378 443
disorder n/a 382 383
disorder n/a 390 411
disorder n/a 434 436
disorder n/a 443 445
low_complexity n/a 452 468
disorder n/a 460 465
low_complexity n/a 468 497
disorder n/a 471 473
disorder n/a 496 497
Pfam FOXO-TAD 497 535
disorder n/a 500 501
disorder n/a 533 534
disorder n/a 552 553
disorder n/a 558 601
disorder n/a 603 611
disorder n/a 615 617
disorder n/a 619 623
disorder n/a 627 628

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession D3ZV21. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAAKLRAHQV DVDPDFAPQS RPRSCTWPLP QPDLAGDEDG ALGAGVAEGS
50
51
EDCGPERRAT APAMAPAPPL GAEVGPLRKA KSSRRNAWGN LSYADLITKA
100
101
IESAPDKRLT LSQIYDWMVR YVPYFKDKGD SNSSAGWKNS IRHNLSLHTR
150
151
FIRVQNEGTG KSSWWMLNPE GGKTGKTPRR RAVSMDNGAK FLRIKGKASK
200
201
KKQLHLPERS PDDSPPGAPA PGPMSASAKW AASPASHASD DYEAWADFRG
250
251
SGRPLLGEAA ELEDDEALEA LAPSSPLMYP SPASALSPAL GARCPGELPR
300
301
LAELGGPLGL HGGGVAGLPD ALLDGAQDAY GPRARAGTPS YFGGCKASAY
350
351
GGGGGFGPPA LGSLRRLPMQ TIQENKQASF APAAAPFRPG ALPALLPPPP
400
401
PAPRPGPLLG APGELALAGA AAAYPGKGAA PYAPPAPSRS ALAHPISLMT
450
451
LPGEAGAAGL APPAHATAFG GPPGGLLLDA LPGPYAAAAA GPLGAGPDRF
500
501
PADLDLDMFS GSLECDVESI ILNDFMDSDE MDFNSTQPCL RLPQAWLGRR
550
551
PLTRAGCRAE GRPAWPGCPG PVPMGPLSSH PDPRVPTPPT QLHWRIQEAT
600
601
PAQLETSLRA ERRGRWEGAL GHLASPVR                        
628
 

Show the unformatted sequence.

Checksums:
CRC64:192256F5142D4609
MD5:755f36f144ecd32ba4b173ea13405d42

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;