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6  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: D4A133_RAT (D4A133)

Summary

This is the summary of UniProt entry D4A133_RAT (D4A133).

Description: H(+)-transporting two-sector ATPase {ECO:0000256|ARBA:ARBA00012473}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 617 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam ATP-synt_ab_N 21 83
Pfam ATP-synt_ab_Xtn 99 221
low_complexity n/a 206 217
Pfam ATP-synt_ab 230 455

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession D4A133. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDFSKLPKIR DEDKESTFGY VHGVSGPVVT ACDMAGAAMY ELVRVGHSEL
50
51
VGEIIRLEGD MATIQVYEET SGVSVGDPVL RTGKPLSVEL GPGIMGAIFD
100
101
GIQRPLSDIS SQTQSIYIPR GVNVSALSRD IKWEFIPSKN LRVGSHITGG
150
151
DIYGIVNENS LIKHKIMLPP RSRGSVTYIA PPGNYDASDV VLELEFEGVK
200
201
EKLSMVQVWP VRQVRPVTEK LPANHPLLTG QRVLDALFPC VQGGTTAIPG
250
251
AFGCGKTVIS QSLSKYSNSD VIIYVGCGER GNEMSEVLRD FPELTMEVDG
300
301
KVESIMKRTA LVANTSNMPV AAREASIYTG ITLSEYFRDM GYHVSMMADS
350
351
TSRWAEALRE ISGRLAEMPA DSGYPAYLGA RLASFYERAG RVKCLGNPER
400
401
EGSVSIVGAV SPPGGDFSDP VTSATLGIVQ VFWGLDKKLA QRKHFPSVNW
450
451
LISYSKYMRA LDEYYDKHFT EFVPLRTKAK EILQEEEDLA EIVQLVGKAS
500
501
LAETDKITLE VAKLIKDDFL QQNGYTPYDR FCPFYKTVGM LSNMISFYDM
550
551
ARRAVETTAQ SDNKITWSII REHMGEILYK LSSMKFKDPV KDGEAKIKAD
600
601
YAQLLEDMQN AFRSLED                                    
617
 

Show the unformatted sequence.

Checksums:
CRC64:5C6FE68005530B50
MD5:1ef98cb7f899171a1934ea05865c8baa

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
ATP-synt_ab 230 - 455 6VQ6 A 230 - 455 Show 3D Structure View in InterPro
B 230 - 455 Show 3D Structure View in InterPro
C 230 - 455 Show 3D Structure View in InterPro
6VQ7 A 230 - 455 Show 3D Structure View in InterPro
B 230 - 455 Show 3D Structure View in InterPro
C 230 - 455 Show 3D Structure View in InterPro
6VQ8 A 230 - 455 Show 3D Structure View in InterPro
B 230 - 455 Show 3D Structure View in InterPro
C 230 - 455 Show 3D Structure View in InterPro
6VQ9 A 230 - 455 Show 3D Structure View in InterPro
B 230 - 455 Show 3D Structure View in InterPro
C 230 - 455 Show 3D Structure View in InterPro
6VQA A 230 - 455 Show 3D Structure View in InterPro
B 230 - 455 Show 3D Structure View in InterPro
C 230 - 455 Show 3D Structure View in InterPro
6VQB A 230 - 455 Show 3D Structure View in InterPro
B 230 - 455 Show 3D Structure View in InterPro
C 230 - 455 Show 3D Structure View in InterPro
ATP-synt_ab_N 21 - 83 6VQ6 A 21 - 83 Show 3D Structure View in InterPro
B 21 - 83 Show 3D Structure View in InterPro
C 21 - 83 Show 3D Structure View in InterPro
6VQ7 A 21 - 83 Show 3D Structure View in InterPro
B 21 - 83 Show 3D Structure View in InterPro
C 21 - 83 Show 3D Structure View in InterPro
6VQ8 A 21 - 83 Show 3D Structure View in InterPro
B 21 - 83 Show 3D Structure View in InterPro
C 21 - 83 Show 3D Structure View in InterPro
6VQ9 A 21 - 83 Show 3D Structure View in InterPro
B 21 - 83 Show 3D Structure View in InterPro
C 21 - 83 Show 3D Structure View in InterPro
6VQA A 21 - 83 Show 3D Structure View in InterPro
B 21 - 83 Show 3D Structure View in InterPro
C 21 - 83 Show 3D Structure View in InterPro
6VQB A 21 - 83 Show 3D Structure View in InterPro
B 21 - 83 Show 3D Structure View in InterPro
C 21 - 83 Show 3D Structure View in InterPro
ATP-synt_ab_Xtn 99 - 221 6VQ6 A 99 - 221 Show 3D Structure View in InterPro
B 99 - 221 Show 3D Structure View in InterPro
C 99 - 221 Show 3D Structure View in InterPro
6VQ7 A 99 - 221 Show 3D Structure View in InterPro
B 99 - 221 Show 3D Structure View in InterPro
C 99 - 221 Show 3D Structure View in InterPro
6VQ8 A 99 - 221 Show 3D Structure View in InterPro
B 99 - 221 Show 3D Structure View in InterPro
C 99 - 221 Show 3D Structure View in InterPro
6VQ9 A 99 - 221 Show 3D Structure View in InterPro
B 99 - 221 Show 3D Structure View in InterPro
C 99 - 221 Show 3D Structure View in InterPro
6VQA A 99 - 221 Show 3D Structure View in InterPro
B 99 - 221 Show 3D Structure View in InterPro
C 99 - 221 Show 3D Structure View in InterPro
6VQB A 99 - 221 Show 3D Structure View in InterPro
B 99 - 221 Show 3D Structure View in InterPro
C 99 - 221 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;