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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: D4A4E8_RAT (D4A4E8)

Summary

This is the summary of UniProt entry D4A4E8_RAT (D4A4E8).

Description: Endonuclease III-like protein 1 {ECO:0000256|HAMAP-Rule:MF_03183}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 300 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 15
low_complexity n/a 6 19
disorder n/a 18 60
low_complexity n/a 40 54
disorder n/a 62 63
disorder n/a 66 72
disorder n/a 102 103
Pfam HhH-GPD 122 260
Pfam HHH 187 216
disorder n/a 241 242
disorder n/a 244 245

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession D4A4E8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNSGLRIVTR SRSRATRIAS EGCREELAPR ETAAEGRKSH KPVRRPRKKQ
50
51
KVHVAYEVAN GEEGEDAEPL KVPVWEPQNW QQQLANIRIM RSKKDAPVDQ
100
101
LGAEQCYDIT APPKVRRYQV LLSLMLSSQT KDQVTAGAMQ RLRARGLTVE
150
151
SILQTDDDLL GRLIYPVGFW RSKVKFIKQT TAILQQRYEG DIPASVAELV
200
201
ALPGVGPKMA HLAMAVAWGT VSGIAVDTHV HRIANRLKWT KKMTKSPEET
250
251
RRNLEEWLPR VLWSEINGLL VGFGQQICLP VHPRCQACLN KALCPAAQGL
300
301
                                                      
300
 

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Checksums:
CRC64:2988E033C6006576
MD5:4cc208644f61a718434821f076652d00

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;