Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: E7F142_DANRE (E7F142)

Summary

This is the summary of UniProt entry E7F142_DANRE (E7F142).

Description: TLC domain-containing 5a {ECO:0000313|Ensembl:ENSDARP00000032799}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 239 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
transmembrane n/a 6 25
Pfam TRAM_LAG1_CLN8 32 212
transmembrane n/a 37 54
transmembrane n/a 74 92
transmembrane n/a 99 118
transmembrane n/a 161 183
transmembrane n/a 190 215

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession E7F142. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSPLVLGVGV CLAGWIALYA LLCYTNGSCG YEWNCRLVTL FHGILAVCIT
50
51
AYIGYIDGPW PFTYPGTKNT PLQISALVVS LGYFIFDMAW CVYFRTEGLV
100
101
MLAHHTMSIL GILLTLWLEE SGIESCAVLF GSEITNPLLQ TRWFLKHSGR
150
151
YDSILGDVVD ILFVALFVFM RIFVGGAMLY CELISPRPKF IIKCGGVAMY
200
201
ALSWVFMADI VRFTYRKYQV WMNRHKMMAE VNGLNVKRD            
239
 

Show the unformatted sequence.

Checksums:
CRC64:17ACBBC27F398458
MD5:a92067ba1ce277faa32cc2d80d17ab61

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;