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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: E7F226_DANRE (E7F226)

Summary

This is the summary of UniProt entry E7F226_DANRE (E7F226).

Description: Arginine-glutamic acid dipeptide (RE) repeats a {ECO:0000313|Ensembl:ENSDARP00000102789}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 1531 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 91
low_complexity n/a 4 34
low_complexity n/a 28 38
low_complexity n/a 64 71
low_complexity n/a 72 83
disorder n/a 96 97
Pfam BAH 102 240
disorder n/a 155 162
disorder n/a 166 167
disorder n/a 169 172
disorder n/a 237 264
Pfam ELM2 243 293
low_complexity n/a 405 418
disorder n/a 406 407
disorder n/a 415 441
low_complexity n/a 436 459
disorder n/a 450 451
Pfam GATA 464 499
disorder n/a 497 1098
Pfam Atrophin-1 525 1530
low_complexity n/a 569 600
low_complexity n/a 636 653
low_complexity n/a 671 679
low_complexity n/a 707 733
low_complexity n/a 729 751
low_complexity n/a 768 787
low_complexity n/a 790 805
low_complexity n/a 830 847
low_complexity n/a 844 871
low_complexity n/a 866 894
low_complexity n/a 905 927
low_complexity n/a 922 939
low_complexity n/a 936 963
low_complexity n/a 965 1005
low_complexity n/a 1003 1022
low_complexity n/a 1055 1078
disorder n/a 1105 1108
disorder n/a 1112 1240
coiled_coil n/a 1117 1165
low_complexity n/a 1120 1168
disorder n/a 1246 1253
disorder n/a 1255 1365
low_complexity n/a 1259 1283
disorder n/a 1369 1428
low_complexity n/a 1382 1398
low_complexity n/a 1390 1406
disorder n/a 1431 1433
disorder n/a 1435 1528
low_complexity n/a 1502 1515
disorder n/a 1530 1531

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession E7F226. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTADKEKDKE RERDRDRDRD REKRDKTRES ESSRPRRSCT LEGGAKNYAE
50
51
SEHSEDDDNE TPGAATAEEA TKKSKKKLPK KKSRYERTEN GEITSFITED
100
101
DIVYRPGDCV YIESRRPNTP YFICSIQDFK LSKRDHLLMN VKWYYRQSEV
150
151
PDSVYQHLVQ DRNNENDSGR ELVITDPVVK SRELFISDYV DTYHAAALRG
200
201
KCNISHFSDI FAAREFKARI DSFFYILGYN PETRRLNSTQ GEIRVGPSHQ
250
251
AKLPELQPFP SPGGQTVTEN EELVWMPGVN DCDLLMYLRA ARSMAAFAGM
300
301
CDGGSTEDGC LAASRDDTTL NALNTLHESS YDAGKALQRL VKKPVPKLIE
350
351
KCWSEDEVKR FIKGLRQYGK NFFRIRKELL PNKETGELIT FYYYWKKTPE
400
401
AASCRAHRRH RRQPVFRRIK TRTASTPVNT PSRPPSSEFL DLSSASEDDF
450
451
DSEDSEQELK GYACRHCFTT TSKDWHHGGR ENILLCTDCR IHFKKYGELP
500
501
PIEKPVDPPP FMFKPVKEED DGLSGKHSMR TRRNRGSMST LRSGRKKQTA
550
551
SPDGRASPTN EDLRSSGRTS PSAASTSSTD SKTDSMKKPS KKTKEEAPSP
600
601
MKSAKRQREK GASDTEESER ASAKKSKTQE ISVPNSPSEC EGEGEGESSD
650
651
GRSVNDEGSS DPKDIDQDNR SSSPSIPSPR DNESDSDSSA QQQILQGQHP
700
701
PVIQCQTGTL PPAPPPAAAA STTPTSGAPS LSSQPSPSIP PTSMPPQQIP
750
751
PAGPLSLIQS GVQRLPSPHS PLQGMPQPPP PSQTCPQALQ PPLHGPMPPM
800
801
GHPLQAGPSH MPHPHALPTQ PFPMAQSQVP PSPLSGQAQA ASLSQQQRPH
850
851
TPPSQSQSSS QSGSQPPREQ PLPPAPLPMP HIKPPPTTPI PQMPNAQSHK
900
901
HPSHPPFPQM PSNLPPPPAL KPLSSLSNHH PPSAHPPPLQ LMSQSQQLQP
950
951
PPVQPPVLTQ SQTLPATGSQ APPPAPPLPS SSSASHSAPS QPPFPPHSFM
1000
1001
PGSSPVLSPS TVPTSVSSSM TTLQQPPPSI SMPLPASVSA PCPGPSTVPP
1050
1051
VQIKEEPLDE TEEPESPPPP QRSPSPPPTI VNTPSHASQS ARFYKHLDRG
1100
1101
YNTCARTDFY FTPLASSKLA KKREEALEKA KREAEQKARE EKEKEREREK
1150
1151
EREREREREK EAERAAKASS SSHESRMGEP PMAGSAHMRT SFDPPPTTIA
1200
1201
TVPPYIGPDT PALRTLSEYA RPHVMSPTNR NHPFFVSLNP TDPLLAYHLP
1250
1251
GLYNADPSMR ERELREREIR EREIRERELR MERMKPGFEV KPPELDSLHP
1300
1301
SANPMEHFAR HGPIGLPPMA GPHPFASFHP GLNPLERERL ALAGPQLRPE
1350
1351
MTYPERLAER LHVERLANDP MARLQMFNVT PHHHQHSHIH SHLHLHQQDP
1400
1401
LHQGGGECLV CPPGSGAHPL VDPLAGGPHL ARFPYPPGAI PNPLLGQPPH
1450
1451
EHEMLRHPVF GTPYPRDLPA GLPPPMSAAH QLQAMHAQSA ELQRLAMEQQ
1500
1501
WLHGHHHMHG GPLPGQEDYY SRLKKESDKQ L                    
1531
 

Show the unformatted sequence.

Checksums:
CRC64:CD98E3CB40B2A38F
MD5:cbd7facb212537a0cc8b6f9c22ff6198

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;