Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: E7F5V3_DANRE (E7F5V3)

Summary

This is the summary of UniProt entry E7F5V3_DANRE (E7F5V3).

Description: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase {ECO:0000256|ARBA:ARBA00019405}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 2511 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam ketoacyl-synt 1 239
Pfam Ketoacyl-synt_C 243 360
disorder n/a 258 261
disorder n/a 291 296
disorder n/a 322 329
disorder n/a 332 334
disorder n/a 359 364
Pfam KAsynt_C_assoc 362 472
disorder n/a 370 372
disorder n/a 406 426
disorder n/a 435 439
disorder n/a 478 481
Pfam Acyl_transf_1 493 810
Pfam PS-DH 855 1113
disorder n/a 861 862
disorder n/a 981 982
low_complexity n/a 1103 1117
disorder n/a 1109 1112
coiled_coil n/a 1135 1155
low_complexity n/a 1185 1197
low_complexity n/a 1214 1227
low_complexity n/a 1280 1297
Pfam ADH_zinc_N 1685 1822
low_complexity n/a 1864 1870
Pfam KR 1892 2071
Pfam PP-binding 2132 2200
low_complexity n/a 2148 2164
disorder n/a 2200 2206
disorder n/a 2208 2210
disorder n/a 2233 2235
Pfam Thioesterase 2245 2501
low_complexity n/a 2383 2393
low_complexity n/a 2492 2502
disorder n/a 2504 2505
disorder n/a 2507 2511

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession E7F5V3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEDIVIAGIS GRLPESNNLE EFWQNLFNGV DMVTEDDRRW KPGLYGLPRR
50
51
NGKLKEIDRF DAAFFGVHPK QAHTMDPQLR LMLEISYEAI VDGGINPVSM
100
101
RGSKTGVYIG VSGSEAGEAF SKDPEELLGY SMTGCQRAMF ANRLSYFFDF
150
151
NGPSTAIDTA CSSSLLALEN AFNAIRHGKC DAALIGGVNL LLKPNTSVQF
200
201
MKLGMLSPEG TCKSFDASGN GYCRSEAAVA VLLTKKSMAK RIYATVLNAG
250
251
NNTDGYKEQG VTFPSGEMQQ RLVRSLYQEA NISPEQVEYI EAHGTGTKVG
300
301
DPQEVNGIVS VFCQSQRDPL LIGSTKSNMG HPEPASGLAA LAKVVLSLEH
350
351
GVWAPNVHFN EPNPDIPALT DGRLCVVSKP TPVRGGIVGI NSFGFGGSNV
400
401
HVILSPHVSD SSDKTPAPSV PRLLQASGRT EEAVTALFSN AQQHQENSSY
450
451
LSLLNDVSGV PTAGMPYRGY TLIGAQGELT EVQQTQPTPR PLWYICSGMG
500
501
TQWAGMGQSL MQLSEFRESI KRSDIALKDT GLCVSRLLME ADESTFEDTV
550
551
HAFVGLAAIQ VAQIDMLRKM GLEPNGIVGH SVGELACGYA DGSLSHSEAI
600
601
LAAYWRGRCI KEANLPPGGM AAVGLTWEEC KAQCPQGVVP ACHNAEDTVT
650
651
ISGPQDSVSK FVAQLKESGV FAKEVRSAGV AFHSYYMASI APALLSALQK
700
701
VIKSPRPRTA RWISTSIPQS DWESPLALYS SAEYHVNNLV SPVLFQEGLN
750
751
HVPDNAVVVE IAPHALLQAI LKRSLKPTCS ILPLMKRGHA NNLEFFLSHV
800
801
GKVYMNGINV DSNKLYPAVK YPVPRGTPLI SPYIQWDHSQ SWDVPKVEDF
850
851
PAGSGGSTSA TVYNIDMNPE SPDYYMIGHC IDGRVLYPAT GYLVLAWRTL
900
901
MRSLGTVMDH TPVTFEDVTI HRATILPKTG SVQLEVRLMP ATNRFEVSEN
950
951
GNLAVSGKVS VLEDSGLDAF HAELNKPITA DNEDPKLRLK SGDIYKELRL
1000
1001
RGYDYGKTFQ GILESNNAGD SGKLHWTGNW VTFLDTMLQM IVVGLPGRSL
1050
1051
RLPTRIRSVC VDPKLHEERV NDYEGDQKAV NVFVNRCLDN ITAGGVQICG
1100
1101
LHATAAPRRQ QQQTPPTLEE FVFVPYEDAD CLRTNEKLAD QLRHCKGLVQ
1150
1151
RLQRKLAKQG VKISIPGLEG ASEGQLIEAE AEKGLLRLLS VLCGLELNGN
1200
1201
LRSELEQTVQ KERDCLLQDP LLNGLLDSQA LRHCLDTALE NSTPGKFKVL
1250
1251
EALAADGRVF SQAVSLLNIQ PMLRLDYTAS DISADQLSAQ QSSLEEQGIS
1300
1301
TAQWDPLQGP VTGGLDGADL VVCNCAVGSA TNPALLIENL TSAAREGGFI
1350
1351
LLHTLLRGDT LGETVAFLTS QNNRKGLLTQ TEWEELFQKA SLNVVMLRKS
1400
1401
YYGSALFLCR RSQQSSQKQP IHIFVDPTDY KWVETLKSTL AESSDIPVWL
1450
1451
IATKGHNGVV GMVNCLRQEP GGNRIRCTFV SNLSKGAAVP SLLPNEKVMK
1500
1501
ALLKKDLVMN VHRDGLWGVF RHQLLTQDLS EELTEQAYVN VLTRGDLSSL
1550
1551
RWIASPLRHF VASSPNVQLC RVYYSSLNFR DIMLATGKLP PDAIPGDVAL
1600
1601
QQCMLGMEFS GRDPSGRRVM GLLPAKGLAT CVDADKRFLW DVPSSWTLEQ
1650
1651
AASVPVVYAT AYYSLVVRGR LRPGESVLIH SGSGGVGQAA IAIALSMRCR
1700
1701
VFTTVGSKEK KQYLQERFPQ LTAESFANSR DSSFEQHVML NTQGKGVDLV
1750
1751
LNSLAEEKLQ ASLRCLARHG RFLEIGKYDL SNNTPLGMAL FLKNVAFHGI
1800
1801
LLDALFEEGN REWEEVSDLL KKGISSGVVQ PLRTTVFERN QVEEAFRYMA
1850
1851
QGKHIGKVLL QVRSEESSSS GPAVSALSIP AICRTFCPAS LSYIITGGLG
1900
1901
GFGLELAQWL TERGARKLVL TSRSGIRNGY QAKRVREWQA MGIQVLVSTS
1950
1951
DVSTLDGTER LITEACRLGP VGGIFHLAMV LKDGMLENLT PQEFIEVNRP
2000
2001
KYDGTINLDS VTRQKCPQLQ QFVVFSSVSC GRGNAGQSNY GFANSTMERI
2050
2051
CEQRRQENLP GLAVQWGAIG DVGVVLETMG GNDAVIGGTL PQRMSSCLEV
2100
2101
LDRFLCQQRP VMSSFVLAEK VVVTKGEGSG QKDLVEAVAH ILGVRDVNSL
2150
2151
NADASLADLG LDSLMGVEVR QTLERDYDIV MAMREIRQLT INKLRELSKQ
2200
2201
SGGKEESPVK RSGAQALLES DLSRMLVNPD GPTMAPLNEV QSAERPLFLV
2250
2251
HPIEGSIAAF RTLTAKLSVP CYGLQCTKAA PLDSIQSLAA YYVECVRQVQ
2300
2301
LEGPYRIAGY SFGACVAFEM CSQLQLAKCP VEYLFLFDGS HSYVAAYTQS
2350
2351
YRAKLTPGKE SEAETEALCA FIQQFTGIEY NKLLETLLPL SDLEARVDKA
2400
2401
VDLITSSHKN VSRDMLHFAA STFYHKLKAA DRYVPTSKYH GNVTLLRAKA
2450
2451
SSEYGDGLGS DYKLHEVCDG KVSVHVIEGD HRTFLEGEGV ESISSIIHSS
2500
2501
LSEPRVSTRE G                                          
2511
 

Show the unformatted sequence.

Checksums:
CRC64:0089228231B3632E
MD5:353f84514d54cdd7d73b8a4e4af3d775

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;