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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: E7F6Z8_DANRE (E7F6Z8)

Summary

This is the summary of UniProt entry E7F6Z8_DANRE (E7F6Z8).

Description: Phosphodiesterase {ECO:0000256|RuleBase:RU363067}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 611 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 3
Pfam PDEase_I_N 81 141
Pfam PDEase_I 226 454
disorder n/a 472 494
disorder n/a 521 611
low_complexity n/a 570 588

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession E7F6Z8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDSLANDTDG LENSLKYSKC DQTEKMWIRL KGMQKYKNTS QRLRCLVKQL
50
51
DKGEVNVVDL RKNIEYAASV LEAVYIDETR RLLDTEDELS DIQADSVPME
100
101
VRDWLASTFT RKMGVVRRRP EEKPRFRSIV HAVQAGIFVE RMYRRTSNMA
150
151
GLTYPPSVIT ALKDVDKWSF DVFKLQEASS DHALKFLVYE LLTRYDLISR
200
201
FRIPVSSLVS FVEALEIGYS KHRNPYHNLI HAADVTQTAH YLMLHTGVMH
250
251
WLTELEILAM VFAAAIHDFE HTGTTNNFHI QTRSEVAILY NDRSVLENHH
300
301
VSAAYRLMQE DEMNILVNLS KDDWRELRTL VIEMVMSTDM SCHFQQIKTM
350
351
RNSLQQPEGI DKAKALSLML HAADISHPAK GWKLHYRWTQ ALMEEFFRQG
400
401
DKEAELGLPF SPLCDRKATM IAQSQIGFID FIVEPTFSVL VDTTEKIISP
450
451
LIEEAVKSGG VRRSSLTGRG SAAVVESVQR HSDRGSNDEC GGSTDYSLCG
500
501
IDQKHVRHLL SEIIQNNKER WKELSVQELA NKQHERMSDL QEEPMRSTQL
550
551
TLSQENHDSE SKSLNELNNT DSTHSSQDSL DQSSQSPTEG AGDASPEEHS
600
601
SETLPWNGKS A                                          
611
 

Show the unformatted sequence.

Checksums:
CRC64:D2B3802B787FA1A9
MD5:a503fe7ad37c35436cb6a583041718cd

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;