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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: E7FAS0_DANRE (E7FAS0)

Summary

This is the summary of UniProt entry E7FAS0_DANRE (E7FAS0).

Description: Phosphodiesterase {ECO:0000256|RuleBase:RU363067}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 777 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 145
low_complexity n/a 4 17
disorder n/a 147 163
Pfam PDE4_UCR 168 284
disorder n/a 189 219
low_complexity n/a 191 204
disorder n/a 244 245
disorder n/a 247 252
disorder n/a 264 265
disorder n/a 289 308
low_complexity n/a 312 323
Pfam PDEase_I 403 643
low_complexity n/a 434 443
disorder n/a 592 593
disorder n/a 595 604
disorder n/a 635 637
disorder n/a 639 777
low_complexity n/a 655 666
coiled_coil n/a 702 729
low_complexity n/a 703 728
low_complexity n/a 756 777

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession E7FAS0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MMEPPPCSKK SLSLSLPVPR EGQATLKPPQ HLWRQPRTPI KIKHRGYSDT
50
51
DRHHHRQIER SNAMDTSDRP GLKKSRMSWP SSFHGTTSAS MSNCAGNKRY
100
101
DGENGPSPGR SPMDSQASPG LVLHPSFPQS QRRESFLYRS DSDYDMSPKT
150
151
MSRNSSINSE GHAEDLIVTP FAQVLASLRT VRSNFTILAN VTTPTTTMRS
200
201
PVTSQPTVPP ATLSDETYQQ LARETLEELD WCLDQLETIQ THRSVSEMAS
250
251
NKFKRMLNRE LSHLSEMSRS GNQVSEYIST TFLDKQNEVE IPSPTLRERE
300
301
KPMSHISGVK KLTHSSSLTS AALPRFGVKT EQEDALAREL NDLNKWGLNI
350
351
FHVAEFSNNR PLSCIMFAIF QERDLLKTFR IPVDTFITYV MTLEDHYHAN
400
401
VAYHNSLHAA DVTQSTHVLL STPALDAVFS DLEILAALFA AAIHDVDHPG
450
451
VSNQFLINTN SELALMYNDE SVLENHHLAV GFKLLHEENC DIFQNLTKRQ
500
501
RQSLRKLVID MVLATDMSKH MSLLADLKTM VETKKVTSSG VLMLDHYNDR
550
551
IQVLRNMVHC ADLSNPTKPL AVYRQWTERI MEEFFQQGDK ERERGMEISP
600
601
MCDKHTASVE KSQVGFIDYI VHPLWETWGD LVHPDAQEIL DTLEDNRDWY
650
651
QSTIPQSPSP PPDRPDNELE SCRNKFQFEL TLEGETVQDG PPSHNHIVIH
700
701
DQDEKKDDEE AEEAEEDEAE EKMEDGEEVT EVMVERSGRR RLQVQSVVEE
750
751
EDERQSDESP VEETEEEEKS SSPTDDT                         
777
 

Show the unformatted sequence.

Checksums:
CRC64:D266907D6D238E36
MD5:7c2abb92f94e9f7cf624e31aa020b826

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;