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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: F1LQQ7_RAT (F1LQQ7)

Summary

This is the summary of UniProt entry F1LQQ7_RAT (F1LQQ7).

Description: Sodium channel protein {ECO:0000256|RuleBase:RU361132}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 1704 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
transmembrane n/a 88 107
Pfam Ion_trans 117 405
transmembrane n/a 119 140
transmembrane n/a 152 176
transmembrane n/a 213 231
low_complexity n/a 234 248
transmembrane n/a 237 259
transmembrane n/a 331 349
transmembrane n/a 369 393
disorder n/a 407 410
Pfam Ion_trans 526 760
transmembrane n/a 528 546
transmembrane n/a 558 579
transmembrane n/a 591 608
transmembrane n/a 614 632
transmembrane n/a 644 665
low_complexity n/a 644 655
transmembrane n/a 729 755
Pfam Na_trans_assoc 762 950
transmembrane n/a 767 787
disorder n/a 798 800
disorder n/a 802 803
disorder n/a 805 806
disorder n/a 829 854
disorder n/a 859 890
low_complexity n/a 882 896
disorder n/a 895 896
disorder n/a 913 914
Pfam Ion_trans 954 1225
transmembrane n/a 955 974
transmembrane n/a 995 1014
transmembrane n/a 1020 1037
transmembrane n/a 1079 1102
transmembrane n/a 1190 1214
Pfam Ion_trans 1271 1528
transmembrane n/a 1273 1291
transmembrane n/a 1303 1325
transmembrane n/a 1337 1356
transmembrane n/a 1362 1380
low_complexity n/a 1363 1374
transmembrane n/a 1392 1420
low_complexity n/a 1392 1412
transmembrane n/a 1496 1522
disorder n/a 1671 1696

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession F1LQQ7. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLTSPEPKGL VPFTAESLEL IKNHIAKKCN EEHEEEDLKP SWGLEAGKKL
50
51
PFAYGTLPQG TVSEPLEDVD PYYYVKRNTF MVLNRNRVIF RFNAVSILCT
100
101
LSPLSSLRRA VIKVLVHPLF RLLILISVLT DSILMCMSNL PEWILAVENT
150
151
LLGIYTFEIL VKVIARGIWA GSFSFLGDLW NWLDFSVTLF ELITRSSPLS
200
201
SLPMFKTIRT LRILKIIPLN HGLQSIVVTL VQCLKKLLGA IALALFFLTV
250
251
SSLFGMGLFM GNLKHKCVRW PQEDGNDVMY NGTGSQYHIL ERENFYYMEG
300
301
ARYALLCGNK TDAGLCPEGY MCVKEGSNPD NGFTSFDNFG WALLAMFRLM
350
351
TQDYPELLYH QILYASGKIY MIFFVLISFW FAFYMASLFL GILTMAYEQE
400
401
KQRASEESRD MDSKCHQTVK EFEEEHEGAE LQCIWFYEEV LDLLGLELCT
450
451
RRMETTQIEM KKRSPTSINT TLDILEDTAL GHKEEPETSR KECPLCWYKF
500
501
TKTCFIWKCS PCWIKLNEFA DRIITHPLFD LFLVICIILN ICFLALEHFP
550
551
MSEELMSLLA IGNLVFIGIY TIEMILKIIA MHPYGYFQIS WHIFDSILVV
600
601
LGLTEMLLAD IEEITVFILV PLIFIKLGKY APPFKNLMRI LGRALVALKD
650
651
LVLLVSIFIY FSAVFGMKLF GRSYKDCVCH VDQDCQRQRW HMSDFLHAYV
700
701
TVFRILCGEW IETLWECMEV AGEAWCIPFY MMVILIGNLL ILYLFVALVS
750
751
SFASYDATTE VSKEAKNLQL AVAWIKMVIN CVLLKILCKE KTVSTEATDQ
800
801
TCDPSVKENI SGHTLSELSN TQTFLRYKDQ SSGTEKTPVT ESESQSLIAS
850
851
PSVSETVPIA SGESDIENLD NKETRSKSAN GSSKEKMKQS SSSECSTVDI
900
901
AISEEEEMVY EHEKSKLHKN GYERKSSAGQ VSRESRNGKI WRNIRKTCCK
950
951
IVENSWFECF IGLVTLLCTG TLALEDIYID QRKTIKIFLE YGDMIFAYIF
1000
1001
ILEMLLKWVA YGFKAYFSNN WYKLDFMVVI VLCLSLIGKT REDLNPLASI
1050
1051
KFLRALRVLS QFERMKVVLR ALIKTTLPAV SVFLVCLMIW LLFSVMGVFL
1100
1101
FAGKFYECID PTRGERFSVF EVMNKSQCEN LVFNESMPWE NAKLNFDNVG
1150
1151
NGFLSLFQVA TFNGWISIMN SAIDSVGVYM QPSFEHSLHM YTYFIIFVVF
1200
1201
GLFLPLCMLI GVIIRNFNKQ KIKQGGSNIF ITVKQKKQYR ALKKLLYADS
1250
1251
QKPAARPRNK FQGFICDVVT HRVFNVIIIL LICFQATTIM IQNDEQSPQI
1300
1301
ETAVFWMNSL FTMLFTLECI LKLTAFRCHY FTSAWNVHDF MVVVFSITDQ
1350
1351
GLLLPLSIGQ YFVPPSLVQL LLLSRIIHVL RPGKGPKVFH DLMLPLMLSL
1400
1401
PALLNIALLI FLVMFIYAIF GMYNFAYVKK EAGINDVSNF ETFGSSMLCL
1450
1451
FQVTTFSGWD GMLDAIFNSQ WSDCDPDKIN PGTQVRGDCG SPSVGIFYFV
1500
1501
SYILISWLII VNMYVVLIME FLSIPSKRKN RTLSEDDFRR FFKVWNRFDP
1550
1551
DRTQYIDSTK LSDFAAALDP PLFMAKPNKG QLVAMDLPMA AGDRIHCLDI
1600
1601
LLAFTKRVMG KDERVEKILS EIESGFMLAN PFKITYEPIT TTLKRKQEAV
1650
1651
SATIIQRAYK SYRLRQSDKK IQDIPEIDDG REDPNSKGVH SGQIEEKASI
1700
1701
QTQI                                                  
1704
 

Show the unformatted sequence.

Checksums:
CRC64:0756CAEA5186E68C
MD5:efe65208a539f09753d6585d427e78e8

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;