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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: F1QXF5_DANRE (F1QXF5)

Summary

This is the summary of UniProt entry F1QXF5_DANRE (F1QXF5).

Description: Sodium channel protein {ECO:0000256|RuleBase:RU361132}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 1996 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 2
disorder n/a 29 56
transmembrane n/a 126 149
Pfam Ion_trans 129 424
transmembrane n/a 194 213
transmembrane n/a 225 246
transmembrane n/a 252 272
transmembrane n/a 390 417
coiled_coil n/a 414 459
low_complexity n/a 422 437
disorder n/a 423 430
disorder n/a 436 439
low_complexity n/a 445 458
disorder n/a 453 456
low_complexity n/a 458 481
disorder n/a 462 514
coiled_coil n/a 481 503
low_complexity n/a 484 507
Pfam Na_trans_cytopl 543 692
disorder n/a 548 550
disorder n/a 576 585
disorder n/a 649 678
Pfam Ion_trans 741 976
transmembrane n/a 743 761
transmembrane n/a 773 796
transmembrane n/a 808 832
low_complexity n/a 829 841
transmembrane n/a 853 881
low_complexity n/a 869 881
transmembrane n/a 911 931
transmembrane n/a 943 966
low_complexity n/a 954 976
Pfam Na_trans_assoc 980 1194
disorder n/a 1023 1034
disorder n/a 1065 1066
disorder n/a 1105 1112
disorder n/a 1114 1116
disorder n/a 1121 1122
disorder n/a 1135 1136
disorder n/a 1138 1150
Pfam Ion_trans 1198 1475
transmembrane n/a 1200 1218
transmembrane n/a 1239 1258
transmembrane n/a 1270 1290
low_complexity n/a 1295 1310
transmembrane n/a 1316 1342
transmembrane n/a 1441 1464
Pfam Ion_trans 1521 1778
transmembrane n/a 1523 1541
transmembrane n/a 1553 1571
transmembrane n/a 1583 1603
transmembrane n/a 1609 1628
low_complexity n/a 1619 1631
transmembrane n/a 1640 1668
transmembrane n/a 1744 1767
disorder n/a 1867 1872
disorder n/a 1877 1879
disorder n/a 1885 1889
disorder n/a 1914 1915
disorder n/a 1918 1930
disorder n/a 1938 1996
coiled_coil n/a 1967 1994
low_complexity n/a 1973 1996

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession F1QXF5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAAQLLVPPG PDSFRPFLPE SLAAIEQRIA EEVAQRPKGE RRPDDDDENG
50
51
PKPNRDLEAG KPLPFIYGDV PPHMLSVPLE DLDTYYSNQK TFIVLNRGKA
100
101
IFRFNATPAL YILSPFNPLR RISIRVLVHS LFSFVIMCTI LTNCAFMTLS
150
151
NPPEWAKNVE YTFTGIYTFE SLIKILARGF CVGKFTFLRD PWNWLDFSVI
200
201
LMAYVTEFVN LGNVSALRTF RVLRALKTIS VIPGLKTIVG ALIQSVKKLS
250
251
DVMILTVFCL SVFALIGLQL FMGNLRQKCV KMPEVNVTDN LTDYSTELHN
300
301
STFNWTEYIS DSNNYYFIPG RRDALLCGNS SDAGQCPEGF TCIKAGRNPD
350
351
YGYTSFDTFS WAFLSLFRLM TQDFWENLYQ QTLRAAGKPY MIFFVLVIFL
400
401
GSFYLVNLIL AVVAMAYDEQ NQATIEEAQQ KEEEFQAMLE QLKRQQEEAQ
450
451
VAAAAATESG EYSGRGGLSE ESSSGGSRLS SKSAKERRNR RKKRKQREEE
500
501
EKADQEKFHK SASEDSIRRP GFRFSIDANR LSYEKKCSTP NQSLLSIRGS
550
551
LFSPRRNSRA SLFSFRGRAR DFGSENDFAD DEHSTFEDSD SRRGSLFVPR
600
601
CVERRSSTVS HCSLTAPRIM LPANGKMHCT VDCNGVVSLV GGTSVPTSPI
650
651
GRLLPEGTTT ESDVRKKRSG SHQPSDYLEE TVARKRAMSV ASILTNTMEE
700
701
LEESRQKCPP CWYKFANSFL IWDCSPAWLK VKEIMNMIVM DPFVDLAITI
750
751
CIVLNTLFMA MEHYPMTTQF SHLLSVGNLV FTGIFTAEMC LKVIALDPYY
800
801
YFQEGWNIFD GIIVSLSLME LGLANVEGLS VLRSFRLLRV FKLAKSWPTL
850
851
NMLIKIIGNS VGALGNLTLV LAIIVFIFAV VGMQLFGKSY RECVCKISES
900
901
CELPRWHMDD FFHSFLIVFR VLCGEWIETM WDCMEVAGQS MCLIVFMMVM
950
951
VIGNLVVLNL FLALLLSSFS ADNLAATDDD SEMNNLQIAV GRIQKGIALV
1000
1001
KSTLRQFLQS LFLAGSKPRS LDEEKPLDDL HSDGKENCLS NHAPVAVDLT
1050
1051
KDYLKEGCVS PGNGVESHVK YGIEEGDYMS FIHNPSLTVT VPIAVGESDF
1100
1101
ENLNTEDFSS ESSDVEGSKE KLPVDTVLSS SEGSTVDIRP PGEGAESVEL
1150
1151
EPEESLDPEA CFTEGCVMRF QCCQVDVEKG KWKSWWILRK TCFIIVEHNW
1200
1201
FESFIIFMIL LSSGALAFED IYIEQRKTIK TVLEYADKVF TYIFILEMLL
1250
1251
KWVAYGFAKY FTNAWCWLDF LIVDVSLVSL VANALGYSEL SAIKSLRTLR
1300
1301
ALRPLRALSR FEGMRVVVNA LLGAIPSIMN VLLVCLIFWL IFSIMGVNLF
1350
1351
AGKYYYCVNI TNDELFPVSV VNNKSDCYAL IQNNDTARWK NVKINFDNVG
1400
1401
AGYLALLQVA TFKGWMDIMY AAVDSRDLEQ QPVYETNLYM YLYFVIFIIF
1450
1451
GSFFTLNLFI GVIIDNFNQQ KKKLGGQDIF MTEEQKKYYN AMKKLGSKKP
1500
1501
QKPIPRPANK FQGLVFDLIT KQAFDIIIMI LICLNMVTMM VETDDQTEDM
1550
1551
DNILYWINLV FIILFTGECV LKMISLRHYF FTIGWNVFDF VVVILSIVGM
1600
1601
FLSEMIEKYF VSPTLFRVIR LARIGRILRL IKGAKGIRTL LFALMMSLPA
1650
1651
LFNIGLLLFL VMFIYAIFGM SNFAYVKREA GIDDMFNFET FGNSMLCLFQ
1700
1701
ITTSAGWDGL LAPILNKQDP DCDSEMEHPG SFYRGNCGNP SVGIFFFVSY
1750
1751
IIICFLIVVN MYIAVILENF SVATEESAEP LSEDDFEMFY EVWERFDPNA
1800
1801
TQFVEYNKLS DFADALDPPL RIAKPNKIQL IAMDLPMVSG DRIHCLDILF
1850
1851
AFTLRVLGEE GEMDALRGQM EDRFMASNPS KVSYEPITTT LRRKQEEMSA
1900
1901
VVIQRAFRRH RIRQTVKKAS EAYRKQLQDG GGHIPEKEVL VIGKFQENSA
1950
1951
SDKTDMTPSS ASPPSYNSVA KSEKDKYEKE RREKEDKAKD ARDRKK    
1996
 

Show the unformatted sequence.

Checksums:
CRC64:E3735ECF55FF2A74
MD5:326d0296a00d01c8079e255b4822206d

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;