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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: AOXC_MOUSE (G3X982)

Summary

This is the summary of UniProt entry AOXC_MOUSE (G3X982).

Description: Aldehyde oxidase 3 EC=1.2.3.1 EC=1.17.3.-
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 1335 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Fer2 12 82
low_complexity n/a 41 56
Pfam Fer2_2 91 165
disorder n/a 139 140
disorder n/a 185 186
disorder n/a 218 219
disorder n/a 229 230
Pfam FAD_binding_5 235 419
Pfam CO_deh_flav_C 426 530
Pfam Ald_Xan_dh_C 594 697
disorder n/a 650 654
low_complexity n/a 673 686
Pfam MoCoBD_1 708 951
Pfam MoCoBD_2 975 1241
transmembrane n/a 1267 1286
low_complexity n/a 1275 1286

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession G3X982. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSPSKESDEL IFFVNGKKVT ERNADPEVNL LFYLRKVIRL TGTKYGCGGG
50
51
DCGACTVMIS RYDPISKRIS HFSATACLVP ICSLHGAAVT TVEGIGSTKT
100
101
RIHPVQERIA KGHGTQCGFC TPGMVMSIYT LLRNHPEPST EQIMETLGGN
150
151
LCRCTGYRPI VESAKSFCPS STCCQMNGEG KCCLDEEKNE PERKNSVCTK
200
201
LYEKKEFQPL DPTQELIFPP ELMRMAEESQ NTVLTFRGER TTWIAPGTLN
250
251
DLLELKMKHP SAPLVIGNTY LGLHMKFTDV SYPIIISPAR ILELFVVTNT
300
301
KQGLTLGAGL SLTQVKNVLS DVVSRLPKEK TQIYCALLKQ LKTLAGQQIR
350
351
NVASLGGHII SRLPTSDLNP ILGIGNCILN VASTEGIQQI PLNDHFLAGV
400
401
PDAILKPEQV LISVFVPRSS KWEFVSAFRQ APRQQNAFAT VNAGMKVVFK
450
451
EDTNTITDLG ILYGGIGATV ISADKSCRQL IGRCWDEEML DDAGKMICEE
500
501
VSLLMAAPGG MEEYRKTLAI SFLFMFYLDV LKQLKTRDPH KYPDISQKLL
550
551
HILEDFPLTM PYGMQSFQDV DFQQPLQDPI GRPIMHQSGI KHATGEAVFC
600
601
DDMSVLPGEL FLAVVTSSKS HAKIISLDAS EALASLGVVD VVTARDVPGD
650
651
NGREEESLYA QDEVICVGQI VCAVAADSYA HAQQAAKKVK IVYQDIEPMI
700
701
VTVQDALQYE SFIGPERKLE QGNVEEAFQC ADQILEGEVH LGGQEHFYME
750
751
TQSVRVVPKG EDKEMDIYVS SQDAAFTQEM VARTLGIPKN RINCHVKRVG
800
801
GAFGGKASKP GLLASVAAVA AQKTGRPIRF ILERRDDMLI TGGRHPLLGK
850
851
YKIGFMNNGK IKAADIQLYI NGGCTPDDSE LVIEYALLKL ENAYKIPNLR
900
901
VRGRVCKTNL PSNTAFRGFG FPQGAFVTET CMSAVAAKCR LPPEKVRELN
950
951
MYRTIDRTIH NQEFDPTNLL QCWEACVENS SYYNRKKAVD EFNQQRFWKK
1000
1001
RGIAIIPMKF SVGFPKTFYY QAAALVQIYT DGSVLVAHGG VELGQGINTK
1050
1051
MIQVASRELK IPMSYIHLDE MSTVTVPNTV TTGASTGADV NGRAVQNACQ
1100
1101
ILMKRLEPII KQNPSGTWEE WVKEAFVQSI SLSATGYFRG YQADMDWEKG
1150
1151
EGDIFPYFVF GAACSEVEID CLTGAHKNIR TDIVMDGSFS INPAVDIGQI
1200
1201
EGAFVQGLGL YTLEELKYSP EGVLYTRGPH QYKIASVTDI PEEFHVSLLT
1250
1251
PTPNPKAIYS SKGLGEAGTF LGCSVFFAIA AAVAAAREER GLSPIWAINS
1300
1301
PATAEVIRMA CEDQFTNLVP QTDSKCCKPW SIPVA                
1335
 

Show the unformatted sequence.

Checksums:
CRC64:29683B03DD3E75E9
MD5:6be05722277199bf659c9a381c29bff5

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Ald_Xan_dh_C 594 - 696 3ZYV B 594 - 696 Show 3D Structure View in InterPro
C 594 - 696 Show 3D Structure View in InterPro
D 594 - 696 Show 3D Structure View in InterPro
594 - 697 3ZYV A 594 - 697 Show 3D Structure View in InterPro
CO_deh_flav_C 426 - 530 3ZYV A 426 - 530 Show 3D Structure View in InterPro
B 426 - 530 Show 3D Structure View in InterPro
C 426 - 530 Show 3D Structure View in InterPro
D 426 - 530 Show 3D Structure View in InterPro
FAD_binding_5 235 - 419 3ZYV A 235 - 419 Show 3D Structure View in InterPro
B 235 - 419 Show 3D Structure View in InterPro
C 235 - 419 Show 3D Structure View in InterPro
D 235 - 419 Show 3D Structure View in InterPro
Fer2 12 - 82 3ZYV A 12 - 82 Show 3D Structure View in InterPro
B 12 - 82 Show 3D Structure View in InterPro
C 12 - 82 Show 3D Structure View in InterPro
D 12 - 82 Show 3D Structure View in InterPro
Fer2_2 91 - 165 3ZYV A 91 - 165 Show 3D Structure View in InterPro
B 91 - 165 Show 3D Structure View in InterPro
C 91 - 165 Show 3D Structure View in InterPro
D 91 - 165 Show 3D Structure View in InterPro
MoCoBD_1 708 - 951 3ZYV A 708 - 951 Show 3D Structure View in InterPro
B 708 - 951 Show 3D Structure View in InterPro
C 708 - 951 Show 3D Structure View in InterPro
D 708 - 951 Show 3D Structure View in InterPro
MoCoBD_2 975 - 1241 3ZYV A 975 - 1241 Show 3D Structure View in InterPro
B 975 - 1241 Show 3D Structure View in InterPro
C 975 - 1241 Show 3D Structure View in InterPro
D 975 - 1241 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;