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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: I6YEL8_MYCTU (I6YEL8)

Summary

This is the summary of UniProt entry I6YEL8_MYCTU (I6YEL8).

Description: Probable conserved integral membrane protein {ECO:0000313|EMBL:CCP45679.1}
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (NCBI taxonomy ID 83332)
Length: 287 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
low_complexity n/a 4 18
transmembrane n/a 6 32
Pfam DsbD 9 221
transmembrane n/a 53 78
transmembrane n/a 84 105
low_complexity n/a 91 113
transmembrane n/a 135 157
transmembrane n/a 169 192
low_complexity n/a 169 195
transmembrane n/a 204 225
low_complexity n/a 210 226
low_complexity n/a 244 255
transmembrane n/a 262 282
low_complexity n/a 267 274

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession I6YEL8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNEALIGLAF AAGLVAALNP CGFAMLPAYL LLVVYGQDSA GRTGPLSAVG
50
51
RAAAATVGMA LGFLTVFGIF GALTISAATA VQRYLPYATV LIGLALIALG
100
101
GWLLLGRGLT ALTPRSLGVR WAPTVRLGSM YGYGISYAVA SLSCTIGPFL
150
151
AVTGAGLRGG SVVGSVAIYL AYVAGLTLVV GVLAVAAATA SSALADRLRR
200
201
ILPFVNRISG ALLVVVGLYV GYYGLYELRL IAGVGANPQD AVIAAAGRLQ
250
251
GALAGWVNQH GAWPWAVLLV VLVVGAFAGT WFRRVRR              
287
 

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Checksums:
CRC64:DC69FA5DF250DF52
MD5:31ae77fcfacb7608b6f5438be537b9d7

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;