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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: O06586_MYCTU (O06586)

Summary

This is the summary of UniProt entry O06586_MYCTU (O06586).

Description: Probable polyketide synthase Pks9 {ECO:0000313|EMBL:CCP44429.1}
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (NCBI taxonomy ID 83332)
Length: 1017 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam ketoacyl-synt 4 40
Pfam ketoacyl-synt 33 222
low_complexity n/a 42 49
disorder n/a 200 201
Pfam Ketoacyl-synt_C 230 347
disorder n/a 310 313
low_complexity n/a 316 335
Pfam KAsynt_C_assoc 349 469
disorder n/a 375 376
disorder n/a 389 390
disorder n/a 393 394
disorder n/a 402 405
low_complexity n/a 470 501
Pfam Acyl_transf_1 504 797
low_complexity n/a 564 581
low_complexity n/a 606 622
low_complexity n/a 668 689
Pfam PP-binding 868 938
low_complexity n/a 971 978
disorder n/a 990 992

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O06586. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MQPTGIAIIG LACRFPTVVS PGDLWDLLRD GREAAGSIDN VADFDADFFN
50
51
LSPREASAMD PRQRLALELT WELLEDAFVV PETLRGQPIA VYLGAMNDDY
100
101
AVLTLAADRV DHHAFAGTSR AIIANRVSFA FGLRGPSVTI DSGQSSSLVA
150
151
VHLACESVRT GEAPLAIAGG VHLNLARETA MLEQEFGAVS PSGHTYAFDE
200
201
RADGYVPGDG GGLVLLKPVQ AALDDGDRIH AIIRGSAVGN AGHSATGLTV
250
251
PSVAGQVDVI RRAMSGAGVD CHQVHYVEAH GTGTKIGDPI EARALGEIFA
300
301
ARQRRPVSVG SVKTNIGHTG GAAGIAGLLK AVLAIENAVI PPSLNYVGAA
350
351
IDLDSLGLRV DTALTPWPVA DEPRRAGVSS FGMGGTNAHV ILEQGPTQSP
400
401
EIVESVAAAG SNAPVAVPWV LAARSPQALT NQAGRLLAHL TADDGLTALD
450
451
VGWSLVSTRS VFDHRAVVVG ADRGRLMAGL AGLAAGEPGA GVVVGRARSV
500
501
GKTVFVFPGQ GSQWLGMGRQ LYGRYSVFAR AFDEVVAVLD GQLRLSVRQV
550
551
MWGADAGLLE STEFAQPALF VVQVALAALL QDWGVLPDLV MGHSVGEIAA
600
601
AYVAGALSLV DAARVVAARG RLMQALPAGG VMVAVAASED EVAPLLTEGV
650
651
CIAAVNAPES VVISGEQAAV GVVVDRLVGL GRRVRRLAVS HAFHSVLMDP
700
701
MVEEFSKVLA DVCVRAPRIG LVSNVTGQLA GAGYGSPAYW VEHVRKPVRF
750
751
FDGVGLAESL GARVFVEVGP GAGLEASVAL LARDRPEVES VLAGVGRLFA
800
801
EGVAVDWSSV FAGLGGRRVE LPTYGFARQR FWLGDNGELS VDQTGKDAGA
850
851
IARLQSLAPP ELQRQLVELV CFHAAIVLGR KSSHDIDPEC AFQDLGFDSM
900
901
SGVELRNRLQ MAIGLPGLSL PRTLIFDYPT ASALAECLGQ LLGGQHESSD
950
951
DESIWQLLKN IPIHQLRRTG LLDKLLLLAG QPEESLAGRT VSDEVIDSLS
1000
1001
PEALIGLALD EDENDIR                                    
1017
 

Show the unformatted sequence.

Checksums:
CRC64:B93A22D8818AE0EC
MD5:88d705b87a0277c7cf947766dfde9589

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;