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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HPS1_MOUSE (O08983)

Summary

This is the summary of UniProt entry HPS1_MOUSE (O08983).

Description: Hermansky-Pudlak syndrome 1 protein homolog
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 704 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Fuz_longin_1 2 159
low_complexity n/a 28 47
disorder n/a 194 195
Pfam Fuz_longin_2 204 409
low_complexity n/a 229 246
disorder n/a 245 313
low_complexity n/a 252 258
disorder n/a 315 350
disorder n/a 501 506
Pfam Fuz_longin_3 544 699

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O08983. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKCVLVATEG AEVLFYWTDE EFAESLRLKL QQSEDEEEEL PVLEDQLSTL
50
51
LAPVIISSMT MLEKLSDTYT CFSTENDNHL YVLHLFGEYL FVAINGDHSE
100
101
SEGDLRRKLC VLKYLFEVHF GLVTVDGQLI RKELRPPDLE ERARVWKHFQ
150
151
RLLGTYSYLR DREQSFAVEA VERLIHPQLC EQSIETLERH VVQAINASPE
200
201
RGGEEVLHAF LLVHCKLLAF YSGHGASTLR PADLLALILL VQDLQPSPGT
250
251
TEEEEEEEDS DSPQRRPKSS QNIPVQQARS QSTSVPTRSS RETDTDSISL
300
301
PEEYFTPAPS PGDQSSGSLV WLDGGTPPSD ALQMAEDTPE GLASHSPELP
350
351
SPRRIFLDAN IKENYCPLVP HTMYCLPLWP GINMVLLTKS PSTPLALILY
400
401
QLLDGFSLLE KKLKEGQEAG SALRSQPFVA DLRQKMDKFI KNRVGQEIQN
450
451
TWLEFKSKAF SRSEPGSSWE LLQVCGKLKR QLCVIYRLSF LVTAPSRGGP
500
501
HLPQHLQDRA QKLMKERLLD WKDFLLVKSR RNVTMVSYLE DFPGLVHFIY
550
551
VDRTTGQMVA PSLSPNEKMS SELGKGPLAA FVKAKVWALV RLARRYLQKG
600
601
CTTLLFQEGD FRCSYFLWFE NDMGYKLQMI EVPVLSDDSV PIGVLGGDYY
650
651
RKLLRYYSKS HPSEPVRCYE LLTLHLSVIP TDLLVQQASQ LARRLGEASR
700
701
VTLP                                                  
704
 

Show the unformatted sequence.

Checksums:
CRC64:CFBB610E3F5A7B89
MD5:a95254fbded686ecb5dbfa3b43fccb77

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;