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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ATN1_MOUSE (O35126)

Summary

This is the summary of UniProt entry ATN1_MOUSE (O35126).

Description: Atrophin-1
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 1175 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Atrophin-1 1 156
disorder n/a 1 757
low_complexity n/a 73 93
low_complexity n/a 155 179
low_complexity n/a 209 218
low_complexity n/a 231 245
low_complexity n/a 236 253
low_complexity n/a 256 286
low_complexity n/a 277 297
low_complexity n/a 301 317
low_complexity n/a 351 372
Pfam Atrophin-1 378 1174
low_complexity n/a 378 396
low_complexity n/a 441 446
low_complexity n/a 467 500
low_complexity n/a 495 504
low_complexity n/a 527 538
low_complexity n/a 547 583
low_complexity n/a 582 609
low_complexity n/a 672 709
low_complexity n/a 714 736
low_complexity n/a 731 743
disorder n/a 762 764
disorder n/a 779 893
coiled_coil n/a 781 830
low_complexity n/a 786 822
disorder n/a 906 978
low_complexity n/a 914 931
low_complexity n/a 960 973
low_complexity n/a 964 978
low_complexity n/a 980 998
disorder n/a 987 992
disorder n/a 999 1020
disorder n/a 1024 1053
low_complexity n/a 1035 1051
disorder n/a 1059 1060
disorder n/a 1076 1077
disorder n/a 1079 1092
low_complexity n/a 1084 1097
disorder n/a 1095 1096
low_complexity n/a 1111 1122
disorder n/a 1115 1117
disorder n/a 1119 1128
disorder n/a 1130 1133
low_complexity n/a 1130 1144
disorder n/a 1139 1140
disorder n/a 1150 1152
disorder n/a 1157 1171
disorder n/a 1174 1175

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O35126. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKTRQNKDSM SMRSGRKKEA PGPREELRSR GRASPGGVST SSSDGKAEKS
50
51
RQTAKKARIE EPSAPKASKQ GRSEEISESE SEETSAPKKT KTEQELPRPQ
100
101
SPSDLDSLDG RSINDDGSSD PRDIDQDNRS TSPSIYSPGS VENDSDSSSG
150
151
LSQGPARPYH PPPLFPPSPP PPDSTPRQPE SGFEPHPSVP PTGYHAPMEP
200
201
PTSRLFQGPP PGAPPTHPQL YPGNASGGVL SGPPMGPKGG AAASSVGAPS
250
251
GGKQHPPPTT PIPISSSGAS GAPPAKPPSA PVGGGSLPSA PPPASFPHVT
300
301
PNLPPPPALR PLNNASASPP GMGAQPIPGH LPSPHAMGQG MSGLPPGPEK
350
351
GPTLAPSPHP LPPASSSAPG PPMRYPYSSS SSSAAASSSS SSSSASQYPA
400
401
SQALPSYPHS FPPPTSMSVS NQPPKYTQPS LPSQAVWSQG PPPPPPYGRL
450
451
LANNNTHPGP FPPTGGQSTA HPAAPTHHHH QQQPQQQHHH GNSGPPPPGA
500
501
YPHPLESSNS HHAHPYNMSP SLGSLRPYPP GPAHLPPPHG QVSYNQAGPN
550
551
GPPVSSSNSS GSSSQASYSC SHPSSSQGPQ GASYPFPPVP PVTTSSATLS
600
601
TVIATVASSP AGYKTASPPG PPQYSKRAPS PGSYKTATPP GYKPGSPPSF
650
651
RTGTPPGYRG TSPPAGPGTF KPGSPTVGPG PLPPAGPSSL SSLPPPPAAP
700
701
TTGPPLTATQ IKQEPAEEYE PPESPVPPAR SPSPPPKVVD VPSHASQSAR
750
751
FNKHLDRGFN SCARSDLYFV PLEGSKLAKK RADLVEKVRR EAEQRAREEK
800
801
EREREREREK EREREKEREL ERSVKLAQEG RAPVECPSLG PVPHRPPFEP
850
851
GSAVATVPPY LGPDTPALRT LSEYARPHVM SPGNRNHPFY VPLGAVDPGL
900
901
LGYNVPALYS SDPAARERER EARERDLRDR LKPGFEVKPS ELEPLHGVPG
950
951
PGLDPFPRHG GLALQPGPPG LHPFPFHPSL GPLERERLAL AAGPALRPDM
1000
1001
SYAERLAAER QHAERVAALG NDPLARLQML NVTPHHHQHS HIHSHLHLHQ
1050
1051
QDAIHAASAS VHPLIDPLAS GSHLTRIPYP AGTLPNPLLP HPLHENEVLR
1100
1101
HQLFAAPYRD LPASLSAPMS AAHQLQAMHA QSAELQRLAL EQQQWLHAHH
1150
1151
PLHSVPLPAQ EDYYSHLKKE SDKPL                           
1175
 

Show the unformatted sequence.

Checksums:
CRC64:8BEFFAB75DDC0F36
MD5:b9ebadf457af688a75e6ab499c95c738

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;