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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: E2F6_HUMAN (O75461)

Summary

This is the summary of UniProt entry E2F6_HUMAN (O75461).

Description: Transcription factor E2F6
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 281 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 2
disorder n/a 8 10
disorder n/a 12 14
Pfam E2F_TDP 64 128
Pfam E2F_CC-MB 143 237
coiled_coil n/a 143 163
disorder n/a 205 223
disorder n/a 233 240
disorder n/a 242 281
low_complexity n/a 248 259
low_complexity n/a 252 278

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O75461. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSQQRPARKL PSLLLDPTEE TVRRRCRDPI NVEGLLPSKI RINLEDNVQY
50
51
VSMRKALKVK RPRFDVSLVY LTRKFMDLVR SAPGGILDLN KVATKLGVRK
100
101
RRVYDITNVL DGIDLVEKKS KNHIRWIGSD LSNFGAVPQQ KKLQEELSDL
150
151
SAMEDALDEL IKDCAQQLFE LTDDKENERL AYVTYQDIHS IQAFHEQIVI
200
201
AVKAPAETRL DVPAPREDSI TVHIRSTNGP IDVYLCEVEQ GQTSNKRSEG
250
251
VGTSSSESTH PEGPEEEENP QQSEELLEVS N                    
281
 

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Checksums:
CRC64:539E049C15AD3508
MD5:b69eb89c85c91eef4511c4663d75b6fd

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.