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10  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: B3AT_HUMAN (P02730)

Summary

This is the summary of UniProt entry B3AT_HUMAN (P02730).

Description: Band 3 anion transport protein
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 911 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 52
coiled_coil n/a 1 21
low_complexity n/a 8 23
disorder n/a 57 61
Pfam Band_3_cyto 86 329
disorder n/a 181 189
disorder n/a 199 207
disorder n/a 210 218
low_complexity n/a 249 261
Pfam HCO3_cotransp 377 566
transmembrane n/a 405 428
transmembrane n/a 449 471
transmembrane n/a 491 516
transmembrane n/a 523 545
low_complexity n/a 523 533
Pfam HCO3_cotransp 555 839
transmembrane n/a 565 584
transmembrane n/a 604 624
transmembrane n/a 661 680
transmembrane n/a 701 724
low_complexity n/a 706 721
transmembrane n/a 761 780
low_complexity n/a 761 775
transmembrane n/a 787 811
transmembrane n/a 831 850
transmembrane n/a 857 878
low_complexity n/a 863 877

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P02730. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEELQDDYED MMEENLEQEE YEDPDIPESQ MEEPAAHDTE ATATDYHTTS
50
51
HPGTHKVYVE LQELVMDEKN QELRWMEAAR WVQLEENLGE NGAWGRPHLS
100
101
HLTFWSLLEL RRVFTKGTVL LDLQETSLAG VANQLLDRFI FEDQIRPQDR
150
151
EELLRALLLK HSHAGELEAL GGVKPAVLTR SGDPSQPLLP QHSSLETQLF
200
201
CEQGDGGTEG HSPSGILEKI PPDSEATLVL VGRADFLEQP VLGFVRLQEA
250
251
AELEAVELPV PIRFLFVLLG PEAPHIDYTQ LGRAAATLMS ERVFRIDAYM
300
301
AQSRGELLHS LEGFLDCSLV LPPTDAPSEQ ALLSLVPVQR ELLRRRYQSS
350
351
PAKPDSSFYK GLDLNGGPDD PLQQTGQLFG GLVRDIRRRY PYYLSDITDA
400
401
FSPQVLAAVI FIYFAALSPA ITFGGLLGEK TRNQMGVSEL LISTAVQGIL
450
451
FALLGAQPLL VVGFSGPLLV FEEAFFSFCE TNGLEYIVGR VWIGFWLILL
500
501
VVLVVAFEGS FLVRFISRYT QEIFSFLISL IFIYETFSKL IKIFQDHPLQ
550
551
KTYNYNVLMV PKPQGPLPNT ALLSLVLMAG TFFFAMMLRK FKNSSYFPGK
600
601
LRRVIGDFGV PISILIMVLV DFFIQDTYTQ KLSVPDGFKV SNSSARGWVI
650
651
HPLGLRSEFP IWMMFASALP ALLVFILIFL ESQITTLIVS KPERKMVKGS
700
701
GFHLDLLLVV GMGGVAALFG MPWLSATTVR SVTHANALTV MGKASTPGAA
750
751
AQIQEVKEQR ISGLLVAVLV GLSILMEPIL SRIPLAVLFG IFLYMGVTSL
800
801
SGIQLFDRIL LLFKPPKYHP DVPYVKRVKT WRMHLFTGIQ IICLAVLWVV
850
851
KSTPASLALP FVLILTVPLR RVLLPLIFRN VELQCLDADD AKATFDEEEG
900
901
RDEYDEVAMP V                                          
911
 

Show the unformatted sequence.

Checksums:
CRC64:35EC3EE7AFF27D2F
MD5:0fc0b14ab719affa50e864ff42e7b0f1

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Band_3_cyto 86 - 329 1HYN P 86 - 329 Show 3D Structure View in InterPro
Q 86 - 329 Show 3D Structure View in InterPro
R 86 - 329 Show 3D Structure View in InterPro
S 86 - 329 Show 3D Structure View in InterPro
4KY9 A 86 - 329 Show 3D Structure View in InterPro
P 86 - 329 Show 3D Structure View in InterPro
HCO3_cotransp 381 - 553 4YZF A 381 - 553 Show 3D Structure View in InterPro
B 381 - 553 Show 3D Structure View in InterPro
C 381 - 553 Show 3D Structure View in InterPro
D 381 - 553 Show 3D Structure View in InterPro
389 - 430 1BNX A 2 - 34 Show 3D Structure View in InterPro
1BZK A 2 - 43 Show 3D Structure View in InterPro
405 - 424 1BTQ A 2 - 21 Show 3D Structure View in InterPro
1BTR A 2 - 21 Show 3D Structure View in InterPro
436 - 456 1BTS A 2 - 22 Show 3D Structure View in InterPro
1BTT A 2 - 22 Show 3D Structure View in InterPro
567 - 839 4YZF A 567 - 839 Show 3D Structure View in InterPro
B 567 - 839 Show 3D Structure View in InterPro
C 567 - 839 Show 3D Structure View in InterPro
D 567 - 839 Show 3D Structure View in InterPro
803 - 835 1BH7 A 9 - 41 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;