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16  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RPC1_YEAST (P04051)

Summary

This is the summary of UniProt entry RPC1_YEAST (P04051).

Description: DNA-directed RNA polymerase III subunit RPC1 EC=2.7.7.6
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (NCBI taxonomy ID 559292)
Length: 1460 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam RNA_pol_Rpb1_1 10 368
disorder n/a 51 53
low_complexity n/a 158 177
disorder n/a 272 273
disorder n/a 279 280
disorder n/a 337 341
Pfam RNA_pol_Rpb1_2 370 537
disorder n/a 431 434
disorder n/a 516 517
disorder n/a 519 520
Pfam RNA_pol_Rpb1_3 540 717
disorder n/a 637 639
Pfam RNA_pol_Rpb1_4 742 848
disorder n/a 756 757
disorder n/a 828 836
disorder n/a 838 840
Pfam RNA_pol_Rpb1_5 855 1384
disorder n/a 1040 1047

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P04051. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKEVVVSETP KRIKGLEFSA LSAADIVAQS EVEVSTRDLF DLEKDRAPKA
50
51
NGALDPKMGV SSSSLECATC HGNLASCHGH FGHLKLALPV FHIGYFKATI
100
101
QILQGICKNC SAILLSETDK RQFLHELRRP GVDNLRRMGI LKKILDQCKK
150
151
QRRCLHCGAL NGVVKKAAAG AGSAALKIIH DTFRWVGKKS APEKDIWVGE
200
201
WKEVLAHNPE LERYVKRCMD DLNPLKTLNL FKQIKSADCE LLGIDATVPS
250
251
GRPETYIWRY LPAPPVCIRP SVMMQDSPAS NEDDLTVKLT EIVWTSSLIK
300
301
AGLDKGISIN NMMEHWDYLQ LTVAMYINSD SVNPAMLPGS SNGGGKVKPI
350
351
RGFCQRLKGK QGRFRGNLSG KRVDFSGRTV ISPDPNLSID EVAVPDRVAK
400
401
VLTYPEKVTR YNRHKLQELI VNGPNVHPGA NYLLKRNEDA RRNLRYGDRM
450
451
KLAKNLQIGD VVERHLEDGD VVLFNRQPSL HRLSILSHYA KIRPWRTFRL
500
501
NECVCTPYNA DFDGDEMNLH VPQTEEARAE AINLMGVKNN LLTPKSGEPI
550
551
IAATQDFITG SYLISHKDSF YDRATLTQLL SMMSDGIEHF DIPPPAIMKP
600
601
YYLWTGKQVF SLLIKPNHNS PVVINLDAKN KVFVPPKSKS LPNEMSQNDG
650
651
FVIIRGSQIL SGVMDKSVLG DGKKHSVFYT ILRDYGPQEA ANAMNRMAKL
700
701
CARFLGNRGF SIGINDVTPA DDLKQKKEEL VEIAYHKCDE LITLFNKGEL
750
751
ETQPGCNEEQ TLEAKIGGLL SKVREEVGDV CINELDNWNA PLIMATCGSK
800
801
GSTLNVSQMV AVVGQQIISG NRVPDGFQDR SLPHFPKNSK TPQSKGFVRN
850
851
SFFSGLSPPE FLFHAISGRE GLVDTAVKTA ETGYMSRRLM KSLEDLSCQY
900
901
DNTVRTSANG IVQFTYGGDG LDPLEMEGNA QPVNFNRSWD HAYNITFNNQ
950
951
DKGLLPYAIM ETANEILGPL EERLVRYDNS GCLVKREDLN KAEYVDQYDA
1000
1001
ERDFYHSLRE YINGKATALA NLRKSRGMLG LLEPPAKELQ GIDPDETVPD
1050
1051
NVKTSVSQLY RISEKSVRKF LEIALFKYRK ARLEPGTAIG AIGAQSIGEP
1100
1101
GTQMTLKTFH FAGVASMNVT LGVPRIKEII NASKVISTPI INAVLVNDND
1150
1151
ERAARVVKGR VEKTLLSDVA FYVQDVYKDN LSFIQVRIDL GTIDKLQLEL
1200
1201
TIEDIAVAIT RASKLKIQAS DVNIIGKDRI AINVFPEGYK AKSISTSAKE
1250
1251
PSENDVFYRM QQLRRALPDV VVKGLPDISR AVINIRDDGK RELLVEGYGL
1300
1301
RDVMCTDGVI GSRTTTNHVL EVFSVLGIEA ARYSIIREIN YTMSNHGMSV
1350
1351
DPRHIQLLGD VMTYKGEVLG ITRFGLSKMR DSVLQLASFE KTTDHLFDAA
1400
1401
FYMKKDAVEG VSECIILGQT MSIGTGSFKV VKGTNISEKD LVPKRCLFES
1450
1451
LSNEAALKAN                                            
1460
 

Show the unformatted sequence.

Checksums:
CRC64:D1697EB2352BCA4F
MD5:085fbf46e3adabc4027d10d249abb705

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
RNA_pol_Rpb1_1 10 - 368 5FJ8 A 10 - 368 Show 3D Structure View in InterPro
5FJ9 A 10 - 368 Show 3D Structure View in InterPro
5FJA A 10 - 368 Show 3D Structure View in InterPro
6CNB A 10 - 368 Show 3D Structure View in InterPro
6CNC A 10 - 368 Show 3D Structure View in InterPro
6CND A 10 - 368 Show 3D Structure View in InterPro
6CNF A 10 - 368 Show 3D Structure View in InterPro
6EU0 A 10 - 368 Show 3D Structure View in InterPro
6EU1 A 10 - 368 Show 3D Structure View in InterPro
6EU2 A 10 - 368 Show 3D Structure View in InterPro
6EU3 A 10 - 368 Show 3D Structure View in InterPro
6F40 A 10 - 368 Show 3D Structure View in InterPro
6F41 A 10 - 368 Show 3D Structure View in InterPro
6F42 A 10 - 368 Show 3D Structure View in InterPro
6F44 A 10 - 368 Show 3D Structure View in InterPro
6TUT A 10 - 368 Show 3D Structure View in InterPro
RNA_pol_Rpb1_2 370 - 537 5FJ8 A 370 - 537 Show 3D Structure View in InterPro
5FJ9 A 370 - 537 Show 3D Structure View in InterPro
5FJA A 370 - 537 Show 3D Structure View in InterPro
6CNB A 370 - 537 Show 3D Structure View in InterPro
6CNC A 370 - 537 Show 3D Structure View in InterPro
6CND A 370 - 537 Show 3D Structure View in InterPro
6CNF A 370 - 537 Show 3D Structure View in InterPro
6EU0 A 370 - 537 Show 3D Structure View in InterPro
6EU1 A 370 - 537 Show 3D Structure View in InterPro
6EU2 A 370 - 537 Show 3D Structure View in InterPro
6EU3 A 370 - 537 Show 3D Structure View in InterPro
6F40 A 370 - 537 Show 3D Structure View in InterPro
6F41 A 370 - 537 Show 3D Structure View in InterPro
6F42 A 370 - 537 Show 3D Structure View in InterPro
6F44 A 370 - 537 Show 3D Structure View in InterPro
6TUT A 370 - 537 Show 3D Structure View in InterPro
RNA_pol_Rpb1_3 540 - 717 5FJ8 A 540 - 717 Show 3D Structure View in InterPro
5FJ9 A 540 - 717 Show 3D Structure View in InterPro
5FJA A 540 - 717 Show 3D Structure View in InterPro
6CNB A 540 - 717 Show 3D Structure View in InterPro
6CNC A 540 - 717 Show 3D Structure View in InterPro
6CND A 540 - 717 Show 3D Structure View in InterPro
6CNF A 540 - 717 Show 3D Structure View in InterPro
6EU0 A 540 - 717 Show 3D Structure View in InterPro
6EU1 A 540 - 717 Show 3D Structure View in InterPro
6EU2 A 540 - 717 Show 3D Structure View in InterPro
6EU3 A 540 - 717 Show 3D Structure View in InterPro
6F40 A 540 - 717 Show 3D Structure View in InterPro
6F41 A 540 - 717 Show 3D Structure View in InterPro
6F42 A 540 - 717 Show 3D Structure View in InterPro
6F44 A 540 - 717 Show 3D Structure View in InterPro
6TUT A 540 - 717 Show 3D Structure View in InterPro
RNA_pol_Rpb1_4 742 - 848 5FJ8 A 742 - 848 Show 3D Structure View in InterPro
5FJ9 A 742 - 848 Show 3D Structure View in InterPro
5FJA A 742 - 848 Show 3D Structure View in InterPro
6CNB A 742 - 848 Show 3D Structure View in InterPro
6CNC A 742 - 848 Show 3D Structure View in InterPro
6CND A 742 - 848 Show 3D Structure View in InterPro
6CNF A 742 - 848 Show 3D Structure View in InterPro
6EU0 A 742 - 848 Show 3D Structure View in InterPro
6EU1 A 742 - 848 Show 3D Structure View in InterPro
6EU2 A 742 - 848 Show 3D Structure View in InterPro
6EU3 A 742 - 848 Show 3D Structure View in InterPro
6F40 A 742 - 848 Show 3D Structure View in InterPro
6F41 A 742 - 848 Show 3D Structure View in InterPro
6F42 A 742 - 848 Show 3D Structure View in InterPro
6F44 A 742 - 848 Show 3D Structure View in InterPro
6TUT A 742 - 848 Show 3D Structure View in InterPro
RNA_pol_Rpb1_5 855 - 1384 5FJ8 A 855 - 1384 Show 3D Structure View in InterPro
5FJ9 A 855 - 1384 Show 3D Structure View in InterPro
5FJA A 855 - 1384 Show 3D Structure View in InterPro
6CNB A 855 - 1384 Show 3D Structure View in InterPro
6CNC A 855 - 1384 Show 3D Structure View in InterPro
6CND A 855 - 1384 Show 3D Structure View in InterPro
6CNF A 855 - 1384 Show 3D Structure View in InterPro
6EU0 A 855 - 1384 Show 3D Structure View in InterPro
6EU1 A 855 - 1384 Show 3D Structure View in InterPro
6EU2 A 855 - 1384 Show 3D Structure View in InterPro
6EU3 A 855 - 1384 Show 3D Structure View in InterPro
6F40 A 855 - 1384 Show 3D Structure View in InterPro
6F41 A 855 - 1384 Show 3D Structure View in InterPro
6F42 A 855 - 1384 Show 3D Structure View in InterPro
6F44 A 855 - 1384 Show 3D Structure View in InterPro
6TUT A 855 - 1384 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;