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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PPBT_HUMAN (P05186)

Summary

This is the summary of UniProt entry PPBT_HUMAN (P05186).

Description: Alkaline phosphatase, tissue-nonspecific isozyme
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 524 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 20
disorder n/a 24 27
Pfam Alk_phosphatase 51 490
disorder n/a 78 80
disorder n/a 130 139
disorder n/a 164 166
disorder n/a 174 175
disorder n/a 183 184
disorder n/a 189 192
disorder n/a 230 240
disorder n/a 300 302
disorder n/a 340 348
disorder n/a 446 449
low_complexity n/a 498 521

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P05186. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MISPFLVLAI GTCLTNSLVP EKEKDPKYWR DQAQETLKYA LELQKLNTNV
50
51
AKNVIMFLGD GMGVSTVTAA RILKGQLHHN PGEETRLEMD KFPFVALSKT
100
101
YNTNAQVPDS AGTATAYLCG VKANEGTVGV SAATERSRCN TTQGNEVTSI
150
151
LRWAKDAGKS VGIVTTTRVN HATPSAAYAH SADRDWYSDN EMPPEALSQG
200
201
CKDIAYQLMH NIRDIDVIMG GGRKYMYPKN KTDVEYESDE KARGTRLDGL
250
251
DLVDTWKSFK PRYKHSHFIW NRTELLTLDP HNVDYLLGLF EPGDMQYELN
300
301
RNNVTDPSLS EMVVVAIQIL RKNPKGFFLL VEGGRIDHGH HEGKAKQALH
350
351
EAVEMDRAIG QAGSLTSSED TLTVVTADHS HVFTFGGYTP RGNSIFGLAP
400
401
MLSDTDKKPF TAILYGNGPG YKVVGGEREN VSMVDYAHNN YQAQSAVPLR
450
451
HETHGGEDVA VFSKGPMAHL LHGVHEQNYV PHVMAYAACI GANLGHCAPA
500
501
SSAGSLAAGP LLLALALYPL SVLF                            
524
 

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Checksums:
CRC64:71B45F17F6211900
MD5:001513c28b7d90db9461b49d1b911d60

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.