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26  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HMOX1_HUMAN (P09601)

Summary

This is the summary of UniProt entry HMOX1_HUMAN (P09601).

Description: Heme oxygenase 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 288 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 22
Pfam Heme_oxygenase 11 216
disorder n/a 24 25
disorder n/a 28 30
disorder n/a 223 259
transmembrane n/a 267 287

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P09601. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MERPQPDSMP QDLSEALKEA TKEVHTQAEN AEFMRNFQKG QVTRDGFKLV
50
51
MASLYHIYVA LEEEIERNKE SPVFAPVYFP EELHRKAALE QDLAFWYGPR
100
101
WQEVIPYTPA MQRYVKRLHE VGRTEPELLV AHAYTRYLGD LSGGQVLKKI
150
151
AQKALDLPSS GEGLAFFTFP NIASATKFKQ LYRSRMNSLE MTPAVRQRVI
200
201
EEAKTAFLLN IQLFEELQEL LTHDTKDQSP SRAPGLRQRA SNKVQDSAPV
250
251
ETPRGKPPLN TRSQAPLLRW VLTLSFLVAT VAVGLYAM             
288
 

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Checksums:
CRC64:AB47827778694064
MD5:7eda63578cd4808b12f5b436753df993

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Heme_oxygenase 11 - 216 1N3U A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
1N45 A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
1NI6 A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
C 11 - 216 NGL View in InterPro
D 11 - 216 NGL View in InterPro
1OYK A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
1OYL A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
1OZE A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
1OZL A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
1OZR A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
1OZW A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
1S13 A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
1S8C A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
C 11 - 216 NGL View in InterPro
D 11 - 216 NGL View in InterPro
1T5P A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
1TWN A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
1TWR A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
1XJZ A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
1XK0 A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
1XK1 A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
1XK2 A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
1XK3 A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
3CZY A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
3HOK A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
3K4F A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
3TGM A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
4WD4 A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
C 11 - 216 NGL View in InterPro
D 11 - 216 NGL View in InterPro
5BTQ A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
6EHA A 11 - 216 NGL View in InterPro
B 11 - 216 NGL View in InterPro
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TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.