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5  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ENTF_ECOLI (P11454)

Summary

This is the summary of UniProt entry ENTF_ECOLI (P11454).

Description: Enterobactin synthase component F EC=2.7.7.-
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
Length: 1293 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Condensation 1 443
low_complexity n/a 97 109
low_complexity n/a 204 222
disorder n/a 208 212
low_complexity n/a 251 258
disorder n/a 331 332
Pfam AMP-binding 461 863
Pfam AMP-binding_C 871 952
disorder n/a 921 922
low_complexity n/a 930 947
disorder n/a 958 969
Pfam PP-binding 978 1042
disorder n/a 1053 1056
Pfam Thioesterase 1066 1290
disorder n/a 1099 1100
disorder n/a 1106 1111
low_complexity n/a 1132 1141
disorder n/a 1172 1185

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P11454. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSQHLPLVAA QPGIWMAEKL SELPSAWSVA HYVELTGEVD SPLLARAVVA
50
51
GLAQADTLRM RFTEDNGEVW QWVDDALTFE LPEIIDLRTN IDPHGTAQAL
100
101
MQADLQQDLR VDSGKPLVFH QLIQVADNRW YWYQRYHHLL VDGFSFPAIT
150
151
RQIANIYCTW LRGEPTPASP FTPFADVVEE YQQYRESEAW QRDAAFWAEQ
200
201
RRQLPPPASL SPAPLPGRSA SADILRLKLE FTDGEFRQLA TQLSGVQRTD
250
251
LALALAALWL GRLCNRMDYA AGFIFMRRLG SAALTATGPV LNVLPLGIHI
300
301
AAQETLPELA TRLAAQLKKM RRHQRYDAEQ IVRDSGRAAG DEPLFGPVLN
350
351
IKVFDYQLDI PDVQAQTHTL ATGPVNDLEL ALFPDVHGDL SIEILANKQR
400
401
YDEPTLIQHA ERLKMLIAQF AADPALLCGD VDIMLPGEYA QLAQLNATQV
450
451
EIPETTLSAL VAEQAAKTPD APALADARYL FSYREMREQV VALANLLRER
500
501
GVKPGDSVAV ALPRSVFLTL ALHAIVEAGA AWLPLDTGYP DDRLKMMLED
550
551
ARPSLLITTD DQLPRFSDVP NLTSLCYNAP LTPQGSAPLQ LSQPHHTAYI
600
601
IFTSGSTGRP KGVMVGQTAI VNRLLWMQNH YPLTGEDVVA QKTPCSFDVS
650
651
VWEFFWPFIA GAKLVMAEPE AHRDPLAMQQ FFAEYGVTTT HFVPSMLAAF
700
701
VASLTPQTAR QSCATLKQVF CSGEALPADL CREWQQLTGA PLHNLYGPTE
750
751
AAVDVSWYPA FGEELAQVRG SSVPIGYPVW NTGLRILDAM MHPVPPGVAG
800
801
DLYLTGIQLA QGYLGRPDLT ASRFIADPFA PGERMYRTGD VARWLDNGAV
850
851
EYLGRSDDQL KIRGQRIELG EIDRVMQALP DVEQAVTHAC VINQAAATGG
900
901
DARQLVGYLV SQSGLPLDTS ALQAQLRETL PPHMVPVVLL QLPQLPLSAN
950
951
GKLDRKALPL PELKAQAPGR APKAGSETII AAAFSSLLGC DVQDADADFF
1000
1001
ALGGHSLLAM KLAAQLSRQV ARQVTPGQVM VASTVAKLAT IIDAEEDSTR
1050
1051
RMGFETILPL REGNGPTLFC FHPASGFAWQ FSVLSRYLDP QWSIIGIQSP
1100
1101
RPNGPMQTAA NLDEVCEAHL ATLLEQQPHG PYYLLGYSLG GTLAQGIAAR
1150
1151
LRARGEQVAF LGLLDTWPPE TQNWQEKEAN GLDPEVLAEI NREREAFLAA
1200
1201
QQGSTSTELF TTIEGNYADA VRLLTTAHSV PFDGKATLFV AERTLQEGMS
1250
1251
PERAWSPWIA ELDIYRQDCA HVDIISPGTF EKIGPIIRAT LNR       
1293
 

Show the unformatted sequence.

Checksums:
CRC64:F3FCBD3836A39358
MD5:fa4c841c1dbdbb5132415b305a9b3ffa

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
AMP-binding 461 - 863 5JA1 A 461 - 863 Show 3D Structure View in InterPro
5JA2 A 461 - 863 Show 3D Structure View in InterPro
5T3D A 461 - 863 Show 3D Structure View in InterPro
AMP-binding_C 871 - 952 5JA1 A 871 - 952 Show 3D Structure View in InterPro
5JA2 A 871 - 952 Show 3D Structure View in InterPro
5T3D A 871 - 952 Show 3D Structure View in InterPro
Condensation 18 - 443 5JA2 A 18 - 443 Show 3D Structure View in InterPro
21 - 443 5JA1 A 21 - 443 Show 3D Structure View in InterPro
4 - 443 5T3D A 4 - 443 Show 3D Structure View in InterPro
PP-binding 978 - 1041 5JA1 A 978 - 1041 Show 3D Structure View in InterPro
978 - 1042 2ROQ A 20 - 84 Show 3D Structure View in InterPro
3TEJ A 978 - 1042 Show 3D Structure View in InterPro
B 978 - 1042 Show 3D Structure View in InterPro
5JA2 A 978 - 1042 Show 3D Structure View in InterPro
5T3D A 978 - 1042 Show 3D Structure View in InterPro
Thioesterase 1066 - 1290 2ROQ A 108 - 332 Show 3D Structure View in InterPro
3TEJ A 1066 - 1290 Show 3D Structure View in InterPro
B 1066 - 1290 Show 3D Structure View in InterPro
5JA1 A 1066 - 1290 Show 3D Structure View in InterPro
5JA2 A 1066 - 1290 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;