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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: B3A2_MOUSE (P13808)

Summary

This is the summary of UniProt entry B3A2_MOUSE (P13808).

Description: Anion exchange protein 2
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 1237 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 275
low_complexity n/a 93 110
low_complexity n/a 112 135
low_complexity n/a 138 151
low_complexity n/a 169 178
low_complexity n/a 200 216
disorder n/a 277 316
low_complexity n/a 296 313
disorder n/a 322 324
Pfam Band_3_cyto 348 616
disorder n/a 356 357
low_complexity n/a 363 376
disorder n/a 394 396
disorder n/a 418 420
disorder n/a 431 434
disorder n/a 445 470
disorder n/a 472 494
low_complexity n/a 483 489
low_complexity n/a 494 505
low_complexity n/a 542 556
disorder n/a 636 645
Pfam HCO3_cotransp 676 1165
transmembrane n/a 705 726
transmembrane n/a 747 770
transmembrane n/a 790 815
transmembrane n/a 822 840
low_complexity n/a 852 866
disorder n/a 854 855
disorder n/a 881 889
transmembrane n/a 897 914
transmembrane n/a 930 950
transmembrane n/a 987 1006
transmembrane n/a 1027 1051
transmembrane n/a 1057 1075
transmembrane n/a 1087 1106
low_complexity n/a 1089 1098
transmembrane n/a 1112 1132
low_complexity n/a 1135 1146
transmembrane n/a 1159 1177
low_complexity n/a 1161 1175
transmembrane n/a 1183 1204

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P13808. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSSAPRRPAS GADSLHTPEP ESLSPGTPGF PEQEEDELRT LGVERFEEIL
50
51
QEAGSRGGEE PGRSYGEEDF EYHRQSSHHI HHPLSTHLPP DARRRKTPQG
100
101
PGRKPRRRPG ASPTGETPTI EEGEEDEEEA SEAEGFRAPP QQPSPATTPS
150
151
AVQFFLQEDE GAERKPERTS PSPPTQTPHQ EAAPRASKGA QTGTLVEEMV
200
201
AVASATAGGD DGGAAGRPLT KAQPGHRSYN LQERRRIGSM TGVEQALLPR
250
251
VPTDESEAQT LATADLDLMK SHRFEDVPGV RRHLVRKNAK GSTQAAREGR
300
301
EPGPTPRARP RAPHKPHEVF VELNELLLDK NQEPQWRETA RWIKFEEDVE
350
351
EETERWGKPH VASLSFRSLL ELRRTLAHGA VLLDLDQQTL PGVAHQVVEQ
400
401
MVISDQIKAE DRANVLRALL LKHSHPSDEK EFSFPRNISA GSLGSLLGHH
450
451
HAQGTESDPH VTEPLIGGVP ETRLEVDRER ELPPPAPPAG ITRSKSKHEL
500
501
KLLEKIPENA EATVVLVGCV EFLSRPTMAF VRLREAVELD AVLEVPVPVR
550
551
FLFLLLGPSS ANMDYHEIGR SISTLMSDKQ FHEAAYLADE RDDLLTAINA
600
601
FLDCSVVLPP SEVQGEELLR SVAHFQRQML KKREEQGRLL PPGAGLEPKS
650
651
AQDKALLQMV EVAGAAEDDP LRRTGRPFGG LIRDVRRRYP HYLSDFRDAL
700
701
DPQCLAAVIF IYFAALSPAI TFGGLLGEKT KDLIGVSELI MSTALQGVVF
750
751
CLLGAQPLLV IGFSGPLLVF EEAFFSFCSS NELEYLVGRV WIGFWLVFLA
800
801
LLMVALEGSF LVRFVSRFTQ EIFAFLISLI FIYETFYKLI KIFQEHPLHG
850
851
CSGSNDSEAG SSSSSNMTWA TTILVPDNSS ASGQSGQEKP RGQPNTALLS
900
901
LVLMAGTFFI AFFLRKFKNS RFFPGRIRRV IGDFGVPIAI LIMVLVDYSI
950
951
EDTYTQKLSV PSGFSVTAPD KRGWVINPLG EKTPFPVWMM VASLLPAVLV
1000
1001
FILIFMETQI TTLIISKKER MLQKGSGFHL DLLLIVAMGG ICALFGLPWL
1050
1051
AAATVRSVTH ANALTVMSKA VAPGDKPKIQ EVKEQRVTGL LVALLVGLSM
1100
1101
VIGDLLRQIP LAVLFGIFLY MGVTSLNGIQ FYERLHLLLM PPKHHPDVTY
1150
1151
VKKVRTMRMH LFTALQLLCL ALLWAVMSTA ASLAFPFILI LTVPLRMVVL
1200
1201
TRIFTEREMK CLDANEAEPV FDECEGVDEY NEMPMPV              
1237
 

Show the unformatted sequence.

Checksums:
CRC64:1A0782C0071782EE
MD5:8adb0f142c2b2964afaff3fe1b44f93c

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;