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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: B3A3_MOUSE (P16283)

Summary

This is the summary of UniProt entry B3A3_MOUSE (P16283).

Description: Anion exchange protein 3
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 1227 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 309
low_complexity n/a 74 83
low_complexity n/a 88 100
low_complexity n/a 104 115
low_complexity n/a 128 151
low_complexity n/a 149 161
low_complexity n/a 194 216
low_complexity n/a 304 316
disorder n/a 324 325
Pfam Band_3_cyto 349 618
disorder n/a 357 358
low_complexity n/a 364 375
disorder n/a 416 423
disorder n/a 428 505
low_complexity n/a 435 448
low_complexity n/a 533 552
disorder n/a 569 570
coiled_coil n/a 624 644
low_complexity n/a 629 639
disorder n/a 638 640
disorder n/a 642 648
disorder n/a 654 657
disorder n/a 659 669
disorder n/a 671 672
Pfam HCO3_cotransp 679 1156
transmembrane n/a 708 730
transmembrane n/a 742 773
transmembrane n/a 793 818
low_complexity n/a 793 809
transmembrane n/a 825 843
disorder n/a 872 880
transmembrane n/a 888 905
transmembrane n/a 925 942
low_complexity n/a 975 996
transmembrane n/a 979 997
transmembrane n/a 1018 1041
low_complexity n/a 1021 1041
transmembrane n/a 1078 1097
transmembrane n/a 1104 1131
transmembrane n/a 1151 1184
low_complexity n/a 1171 1195
disorder n/a 1206 1208
disorder n/a 1214 1216

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P16283. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MANGVIPPPG GASPLPQVRV PLEEPPLGPD VEEEDDDLGK TLAVSRFGDL
50
51
ISKTPAWDPE KPSRSYSERD FEFHRHTSHH THHPLSARLP PPHKLRRPPP
100
101
TSARHTRRKR KKEKTSAPPS EGTPPIQEEG GAGAEEEEEE EEEEEGESEA
150
151
EPVEPLPPGP PQKAKFSIGS DEDDSPGLPV KAPCAKALPS VGLQSDQSPQ
200
201
RSGSSPSPRA RASRISTEKS RPWSPSASYD LRERLCPGSA LGNPGPEQRV
250
251
PTDEAEAQML GSADLDDMKS HRLEDNPGVR RHLVKKPSRI QGGRGSPSGL
300
301
APILRRKKKK KKLDRRPHEV FVELNELMLD RSQEPHWRET ARWIKFEEDV
350
351
EEETERWGKP HVASLSFRSL LELRRTIAQG AALLDLEQTT LPGIAHLVVE
400
401
TMIVSDQIRP EDRASVLRTL LLKHSHPNDD KDSGFFPRNP SSSSVNSVLG
450
451
NHHPTPSHGP DGAVPTMADD QGEPAPLWPH DPDAKEKPLH MPGGDGHRGK
500
501
SLKLLEKIPE DAEATVVLVG CVPFLEQPAA AFVRLSEAVL LESVLEVPVP
550
551
VRFLFVMLGP SHTSTDYHEL GRSIATLMSD KLFHEAAYQA DDRQDLLGAI
600
601
SEFLDGSIVI PPSEVEGRDL LRSVAAFQRE LLRKRREREQ TKVEMTTRGG
650
651
YAAPGKELSL EMGGSEATSE DDPLQRTGSV FGGLVRDVKR RYPHYPSDLR
700
701
DALHSQCVAA VLFIYFAALS PAITFGGLLG EKTEGLMGVS ELIVSTAVLG
750
751
VLFSLLGAQP LLVVGFSGPL LVFEEAFFKF CRAQDLEYLT GRVWVGLWLV
800
801
VFVLALVAAE GSFLVRYISP FTQEIFAFLI SLIFIYETFH KLYKVFTEHP
850
851
LLPFYPPDEA LETGLELNSS ALPPTEGPPG PRNQPNTALL SLILMLGTFL
900
901
IAFFLRKFRN SRFLGGKARR IIGDFGIPIS ILVMVLVDYS ITDTYTQKLT
950
951
VPTGLSVTSP HKRTWFIPPL GSARPFPPWM MVAAAVPALL VLILIFMETQ
1000
1001
ITALIVSQKA RRLLKGSGFH LDLLLIGSLG GLCGLFGLPW LTAATVRSVT
1050
1051
HVNALTVMRT AIAPGDKPQI QEVREQRVTG VLIASLVGLS IVMGAVLRRI
1100
1101
PLAVLFGIFL YMGVTSLSGI QLSQRLLLIF MPAKHHPEQP YVTKVKTWRM
1150
1151
HLFTCIQLGC IALLWVVKST AASLAFPFLL LLTVPLRRCL LPRLFQDREL
1200
1201
QALDSEDAEP NFDEDGQDEY NELHMPV                         
1227
 

Show the unformatted sequence.

Checksums:
CRC64:68BC64B72E5FDC55
MD5:ea5eb7c6bb9b7daa6cef3848924e7d86

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;