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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: KCC4_YEAST (P25389)

Summary

This is the summary of UniProt entry KCC4_YEAST (P25389).

Description: Probable serine/threonine-protein kinase KCC4 EC=2.7.11.1
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (NCBI taxonomy ID 559292)
Length: 1037 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 11
disorder n/a 14 15
Pfam Pkinase 21 285
disorder n/a 34 35
disorder n/a 343 345
disorder n/a 371 429
low_complexity n/a 371 404
low_complexity n/a 413 433
disorder n/a 431 437
disorder n/a 439 493
low_complexity n/a 471 483
low_complexity n/a 487 504
disorder n/a 495 498
coiled_coil n/a 537 564
disorder n/a 542 568
disorder n/a 570 571
disorder n/a 626 643
disorder n/a 675 685
disorder n/a 692 697
disorder n/a 701 702
disorder n/a 706 722
disorder n/a 745 833
disorder n/a 835 840
disorder n/a 845 916
low_complexity n/a 892 908
Pfam Fungal_KA1 919 1036
low_complexity n/a 1010 1023

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P25389. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTVANTETHS AAKPSSTIGP WKLGETLGFG STGKVQLAQH ERTGHRTAVK
50
51
VISKSIFNNN GNHSNDDSVL PYNIEREIVI MKLLSHPNVL SLYDVWETNN
100
101
NLYLILEYAE KGELFNLLVD HGPLPEREAI NCFRQIIIGI SYCHALGIVH
150
151
RDLKPENLLL DSFYNIKIAD FGMAALQTDA DLLETSCGSP HYAAPEIVSG
200
201
LPYEGFASDV WSCGVILFAL LTGRLPFDEE NGNVRDLLLK VQKGQFEMPN
250
251
DTEISRDAQD LIGKILVVDP RQRIKIRDIL SHPLLKKYQT IKDSKSIKDL
300
301
PRENTYLYPL ADSNNHTSAS IDDSILQNLV VLWHGRHADD IVSKLKENGT
350
351
NKEKILYALL YRFKLDSVRG SNKKNRNKIK KTKKNKRSST LSSSSSLLLN
400
401
NRSIQSTPRR RTSKRHSREF SSSRKRSSFL LSSNPTDSSP IPLRSSKRIT
450
451
HINVASANTQ ATPSGVPNPH KRNSKKRSSK RLSYMPNTKR SSLTSKSLSN
500
501
FTNLIDDDDW EYIEKDAKRT SSNFATLIDE IFEPEKFELA KREKAELQRK
550
551
VQEAKRQSVN AQKINEDEFG SEVSDGMKEL KKINDKVSSP LINYEFSQQE
600
601
LLQDIDTLLT NRYQLSSYTR PISRLDPGLT PVTETLPNNL KEKTALLQDT
650
651
EKKIIETIRR SKFLGSLLNV RGGLSPGKSE LAPIEESPIV STTPLIYNDR
700
701
MEPRRISDVE VPHFTRKSKH FTTANNRRSV LSLYAKDSIK DLNEFLIKED
750
751
PDLPPQGSTD NESRSEDPEI AESITDSRNI QYDEDDSKDG DNVNNDNILS
800
801
DFPQGVGISQ EYDMKDKNPN QSPISKSAEP TLVVKLPSLS SFQGKNASGL
850
851
GLYQREPSKV TLPSLTSNNS SVGENIEDGA EKGTESEKIA ASLSDDDLKE
900
901
DNDKKDNDTV NAPTTVKKPP NSVLLKKFSK GKILELEIHA KIPEKRLYEG
950
951
LHKLLEGWKQ YGLKNLVFNI TNMIITGKLV NDSILFLRST LFEIMVLPNG
1000
1001
DGRSLIKFNK KTGSTKTLTK LATEIQIILQ KEGVLDK              
1037
 

Show the unformatted sequence.

Checksums:
CRC64:2F5FF36DA8C5B1A3
MD5:4e8876003cd568941b87bb3d3185565f

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Fungal_KA1 919 - 1036 3OSM A 919 - 1036 Show 3D Structure View in InterPro
3OST A 919 - 1036 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;