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6  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: YIDC_ECOLI (P25714)

Summary

This is the summary of UniProt entry YIDC_ECOLI (P25714).

Description: Membrane protein insertase YidC
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
Length: 548 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 24
disorder n/a 26 51
low_complexity n/a 30 50
disorder n/a 54 55
Pfam YidC_periplas 60 343
disorder n/a 83 85
disorder n/a 94 95
disorder n/a 110 135
disorder n/a 151 153
low_complexity n/a 172 183
Pfam 60KD_IMP 354 533
transmembrane n/a 354 373
transmembrane n/a 417 440
transmembrane n/a 464 482
transmembrane n/a 494 519
disorder n/a 546 548

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P25714. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDSQRNLLVI ALLFVSFMIW QAWEQDKNPQ PQAQQTTQTT TTAAGSAADQ
50
51
GVPASGQGKL ISVKTDVLDL TINTRGGDVE QALLPAYPKE LNSTQPFQLL
100
101
ETSPQFIYQA QSGLTGRDGP DNPANGPRPL YNVEKDAYVL AEGQNELQVP
150
151
MTYTDAAGNT FTKTFVLKRG DYAVNVNYNV QNAGEKPLEI SSFGQLKQSI
200
201
TLPPHLDTGS SNFALHTFRG AAYSTPDEKY EKYKFDTIAD NENLNISSKG
250
251
GWVAMLQQYF ATAWIPHNDG TNNFYTANLG NGIAAIGYKS QPVLVQPGQT
300
301
GAMNSTLWVG PEIQDKMAAV APHLDLTVDY GWLWFISQPL FKLLKWIHSF
350
351
VGNWGFSIII ITFIVRGIMY PLTKAQYTSM AKMRMLQPKI QAMRERLGDD
400
401
KQRISQEMMA LYKAEKVNPL GGCFPLLIQM PIFLALYYML MGSVELRQAP
450
451
FALWIHDLSA QDPYYILPIL MGVTMFFIQK MSPTTVTDPM QQKIMTFMPV
500
501
IFTVFFLWFP SGLVLYYIVS NLVTIIQQQL IYRGLEKRGL HSREKKKS  
548
 

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Checksums:
CRC64:95EBC5DAB4F2FCFB
MD5:d9725ef94d90a026d20113b1739c3cf0

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
60KD_IMP 354 - 528 5M5H A 354 - 528 Show 3D Structure View in InterPro
354 - 529 6AL2 B 354 - 529 Show 3D Structure View in InterPro
354 - 532 4UTQ A 354 - 532 Show 3D Structure View in InterPro
5MG3 C 354 - 532 Show 3D Structure View in InterPro
6AL2 A 354 - 532 Show 3D Structure View in InterPro
YidC_periplas 333 - 343 5M5H A 333 - 343 Show 3D Structure View in InterPro
60 - 329 3BS6 A 60 - 329 Show 3D Structure View in InterPro
B 60 - 329 Show 3D Structure View in InterPro
60 - 340 3BLC A 60 - 340 Show 3D Structure View in InterPro
B 60 - 340 Show 3D Structure View in InterPro
60 - 343 5MG3 C 60 - 343 Show 3D Structure View in InterPro
6AL2 A 60 - 343 Show 3D Structure View in InterPro
B 60 - 343 Show 3D Structure View in InterPro
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The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;