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15  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MPIP2_HUMAN (P30305)

Summary

This is the summary of UniProt entry MPIP2_HUMAN (P30305).

Description: M-phase inducer phosphatase 2 EC=3.1.3.48
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 580 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 22
disorder n/a 24 28
low_complexity n/a 26 43
disorder n/a 30 36
disorder n/a 43 71
disorder n/a 73 78
low_complexity n/a 77 95
low_complexity n/a 88 107
disorder n/a 89 132
Pfam M-inducer_phosp 113 383
disorder n/a 160 205
low_complexity n/a 178 190
disorder n/a 209 212
disorder n/a 214 222
disorder n/a 228 233
disorder n/a 235 240
disorder n/a 248 249
disorder n/a 253 298
disorder n/a 330 332
disorder n/a 337 369
low_complexity n/a 356 366
Pfam Rhodanese 418 531

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P30305. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEVPQPEPAP GSALSPAGVC GGAQRPGHLP GLLLGSHGLL GSPVRAAASS
50
51
PVTTLTQTMH DLAGLGSETP KSQVGTLLFR SRSRLTHLSL SRRASESSLS
100
101
SESSESSDAG LCMDSPSPMD PHMAEQTFEQ AIQAASRIIR NEQFAIRRFQ
150
151
SMPVRLLGHS PVLRNITNSQ APDGRRKSEA GSGAASSSGE DKENDGFVFK
200
201
MPWKPTHPSS THALAEWASR REAFAQRPSS APDLMCLSPD RKMEVEELSP
250
251
LALGRFSLTP AEGDTEEDDG FVDILESDLK DDDAVPPGME SLISAPLVKT
300
301
LEKEEEKDLV MYSKCQRLFR SPSMPCSVIR PILKRLERPQ DRDTPVQNKR
350
351
RRSVTPPEEQ QEAEEPKARV LRSKSLCHDE IENLLDSDHR ELIGDYSKAF
400
401
LLQTVDGKHQ DLKYISPETM VALLTGKFSN IVDKFVIVDC RYPYEYEGGH
450
451
IKTAVNLPLE RDAESFLLKS PIAPCSLDKR VILIFHCEFS SERGPRMCRF
500
501
IRERDRAVND YPSLYYPEMY ILKGGYKEFF PQHPNFCEPQ DYRPMNHEAF
550
551
KDELKTFRLK TRSWAGERSR RELCSRLQDQ                      
580
 

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Checksums:
CRC64:EDE24B0E84AC1BE3
MD5:e908c1d9a523f06bdb6de0d67d594b64

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Rhodanese 418 - 531 1CWR A 404 - 517 NGL View in InterPro
1CWS A 404 - 517 NGL View in InterPro
1CWT A 404 - 517 NGL View in InterPro
1QB0 A 404 - 517 NGL View in InterPro
1YM9 A 404 - 517 NGL View in InterPro
1YMD A 404 - 517 NGL View in InterPro
1YMK A 404 - 517 NGL View in InterPro
1YML A 404 - 517 NGL View in InterPro
1YS0 A 404 - 517 NGL View in InterPro
2A2K A 404 - 517 NGL View in InterPro
2IFD A 404 - 517 NGL View in InterPro
2IFV A 404 - 517 NGL View in InterPro
2UZQ A 404 - 517 NGL View in InterPro
B 404 - 517 NGL View in InterPro
C 404 - 517 NGL View in InterPro
D 404 - 517 NGL View in InterPro
E 404 - 517 NGL View in InterPro
F 404 - 517 NGL View in InterPro
4WH7 A 404 - 517 NGL View in InterPro
4WH9 A 404 - 517 NGL View in InterPro
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TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.