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41  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SYUA_HUMAN (P37840)

Summary

This is the summary of UniProt entry SYUA_HUMAN (P37840).

Description: Alpha-synuclein
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 140 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam Synuclein 1 131
low_complexity n/a 10 23
disorder n/a 26 27
disorder n/a 50 56
low_complexity n/a 63 78
disorder n/a 97 140

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P37840. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH
50
51
GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL
100
101
GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA           
140
 

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Checksums:
CRC64:6BB2F12128931663
MD5:90cc5e82b1e80478857674f92aa13efa

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Synuclein 1 - 10 6CT7 S 1 - 10 NGL View in InterPro
T 1 - 10 NGL View in InterPro
1 - 100 6L1T A 1 - 100 NGL View in InterPro
B 1 - 100 NGL View in InterPro
C 1 - 100 NGL View in InterPro
D 1 - 100 NGL View in InterPro
E 1 - 100 NGL View in InterPro
F 1 - 100 NGL View in InterPro
G 1 - 100 NGL View in InterPro
H 1 - 100 NGL View in InterPro
I 1 - 100 NGL View in InterPro
J 1 - 100 NGL View in InterPro
6L1U A 1 - 100 NGL View in InterPro
B 1 - 100 NGL View in InterPro
C 1 - 100 NGL View in InterPro
D 1 - 100 NGL View in InterPro
E 1 - 100 NGL View in InterPro
F 1 - 100 NGL View in InterPro
G 1 - 100 NGL View in InterPro
H 1 - 100 NGL View in InterPro
I 1 - 100 NGL View in InterPro
J 1 - 100 NGL View in InterPro
K 1 - 100 NGL View in InterPro
L 1 - 100 NGL View in InterPro
M 1 - 100 NGL View in InterPro
N 1 - 100 NGL View in InterPro
O 1 - 100 NGL View in InterPro
1 - 11 3Q29 A 372 - 382 NGL View in InterPro
1 - 12 2JN5 A 1 - 12 NGL View in InterPro
1 - 131 1XQ8 A 1 - 131 NGL View in InterPro
2KKW A 1 - 131 NGL View in InterPro
2N0A A 1 - 131 NGL View in InterPro
B 1 - 131 NGL View in InterPro
C 1 - 131 NGL View in InterPro
D 1 - 131 NGL View in InterPro
E 1 - 131 NGL View in InterPro
F 1 - 131 NGL View in InterPro
G 1 - 131 NGL View in InterPro
H 1 - 131 NGL View in InterPro
I 1 - 131 NGL View in InterPro
J 1 - 131 NGL View in InterPro
1 - 14 3Q29 C 372 - 385 NGL View in InterPro
1 - 19 2M55 B 201 - 219 NGL View in InterPro
3Q25 A 372 - 390 NGL View in InterPro
10 - 42 3Q26 A 372 - 404 NGL View in InterPro
14 - 94 6XYO A 14 - 94 NGL View in InterPro
C 14 - 94 NGL View in InterPro
E 14 - 94 NGL View in InterPro
G 14 - 94 NGL View in InterPro
I 14 - 94 NGL View in InterPro
6XYP A 14 - 94 NGL View in InterPro
C 14 - 94 NGL View in InterPro
E 14 - 94 NGL View in InterPro
G 14 - 94 NGL View in InterPro
I 14 - 94 NGL View in InterPro
6XYQ A 14 - 94 NGL View in InterPro
C 14 - 94 NGL View in InterPro
E 14 - 94 NGL View in InterPro
G 14 - 94 NGL View in InterPro
I 14 - 94 NGL View in InterPro
14 - 96 6RT0 F 14 - 96 NGL View in InterPro
G 14 - 96 NGL View in InterPro
H 14 - 96 NGL View in InterPro
I 14 - 96 NGL View in InterPro
J 14 - 96 NGL View in InterPro
6SST A 14 - 96 NGL View in InterPro
B 14 - 96 NGL View in InterPro
C 14 - 96 NGL View in InterPro
D 14 - 96 NGL View in InterPro
E 14 - 96 NGL View in InterPro
F 14 - 96 NGL View in InterPro
G 14 - 96 NGL View in InterPro
H 14 - 96 NGL View in InterPro
I 14 - 96 NGL View in InterPro
J 14 - 96 NGL View in InterPro
6SSX A 14 - 96 NGL View in InterPro
B 14 - 96 NGL View in InterPro
C 14 - 96 NGL View in InterPro
D 14 - 96 NGL View in InterPro
E 14 - 96 NGL View in InterPro
F 14 - 96 NGL View in InterPro
G 14 - 96 NGL View in InterPro
H 14 - 96 NGL View in InterPro
I 14 - 96 NGL View in InterPro
J 14 - 96 NGL View in InterPro
14 - 97 6RT0 A 14 - 97 NGL View in InterPro
B 14 - 97 NGL View in InterPro
C 14 - 97 NGL View in InterPro
D 14 - 97 NGL View in InterPro
E 14 - 97 NGL View in InterPro
21 - 99 6XYO B 21 - 99 NGL View in InterPro
D 21 - 99 NGL View in InterPro
F 21 - 99 NGL View in InterPro
H 21 - 99 NGL View in InterPro
J 21 - 99 NGL View in InterPro
31 - 41 5CRW B 31 - 41 NGL View in InterPro
35 - 56 4BXL C 35 - 56 NGL View in InterPro
36 - 98 6UFR A 36 - 98 NGL View in InterPro
B 36 - 98 NGL View in InterPro
C 36 - 98 NGL View in InterPro
D 36 - 98 NGL View in InterPro
E 36 - 98 NGL View in InterPro
F 36 - 98 NGL View in InterPro
G 36 - 98 NGL View in InterPro
H 36 - 98 NGL View in InterPro
I 36 - 98 NGL View in InterPro
J 36 - 98 NGL View in InterPro
36 - 99 6PEO A 36 - 99 NGL View in InterPro
B 36 - 99 NGL View in InterPro
C 36 - 99 NGL View in InterPro
D 36 - 99 NGL View in InterPro
E 36 - 99 NGL View in InterPro
6PES A 36 - 99 NGL View in InterPro
B 36 - 99 NGL View in InterPro
C 36 - 99 NGL View in InterPro
D 36 - 99 NGL View in InterPro
E 36 - 99 NGL View in InterPro
6XYP B 36 - 99 NGL View in InterPro
D 36 - 99 NGL View in InterPro
F 36 - 99 NGL View in InterPro
H 36 - 99 NGL View in InterPro
J 36 - 99 NGL View in InterPro
6XYQ B 36 - 99 NGL View in InterPro
D 36 - 99 NGL View in InterPro
F 36 - 99 NGL View in InterPro
H 36 - 99 NGL View in InterPro
J 36 - 99 NGL View in InterPro
37 - 56 3Q27 A 378 - 397 NGL View in InterPro
37 - 96 6OSM A 37 - 96 NGL View in InterPro
B 37 - 96 NGL View in InterPro
C 37 - 96 NGL View in InterPro
D 37 - 96 NGL View in InterPro
E 37 - 96 NGL View in InterPro
F 37 - 96 NGL View in InterPro
G 37 - 96 NGL View in InterPro
H 37 - 96 NGL View in InterPro
I 37 - 96 NGL View in InterPro
J 37 - 96 NGL View in InterPro
37 - 97 6OSJ A 37 - 97 NGL View in InterPro
B 37 - 97 NGL View in InterPro
C 37 - 97 NGL View in InterPro
D 37 - 97 NGL View in InterPro
E 37 - 97 NGL View in InterPro
F 37 - 97 NGL View in InterPro
G 37 - 97 NGL View in InterPro
H 37 - 97 NGL View in InterPro
I 37 - 97 NGL View in InterPro
J 37 - 97 NGL View in InterPro
37 - 99 6A6B A 37 - 99 NGL View in InterPro
B 37 - 99 NGL View in InterPro
C 37 - 99 NGL View in InterPro
D 37 - 99 NGL View in InterPro
E 37 - 99 NGL View in InterPro
F 37 - 99 NGL View in InterPro
G 37 - 99 NGL View in InterPro
H 37 - 99 NGL View in InterPro
I 37 - 99 NGL View in InterPro
J 37 - 99 NGL View in InterPro
K 37 - 99 NGL View in InterPro
L 37 - 99 NGL View in InterPro
6LRQ A 37 - 99 NGL View in InterPro
B 37 - 99 NGL View in InterPro
C 37 - 99 NGL View in InterPro
D 37 - 99 NGL View in InterPro
E 37 - 99 NGL View in InterPro
F 37 - 99 NGL View in InterPro
38 - 95 6FLT A 38 - 95 NGL View in InterPro
B 38 - 95 NGL View in InterPro
C 38 - 95 NGL View in InterPro
D 38 - 95 NGL View in InterPro
E 38 - 95 NGL View in InterPro
F 38 - 95 NGL View in InterPro
G 38 - 95 NGL View in InterPro
H 38 - 95 NGL View in InterPro
I 38 - 95 NGL View in InterPro
J 38 - 95 NGL View in InterPro
6H6B A 38 - 95 NGL View in InterPro
B 38 - 95 NGL View in InterPro
C 38 - 95 NGL View in InterPro
D 38 - 95 NGL View in InterPro
E 38 - 95 NGL View in InterPro
F 38 - 95 NGL View in InterPro
G 38 - 95 NGL View in InterPro
H 38 - 95 NGL View in InterPro
I 38 - 95 NGL View in InterPro
J 38 - 95 NGL View in InterPro
38 - 97 6CU7 A 38 - 97 NGL View in InterPro
B 38 - 97 NGL View in InterPro
C 38 - 97 NGL View in InterPro
D 38 - 97 NGL View in InterPro
E 38 - 97 NGL View in InterPro
F 38 - 97 NGL View in InterPro
G 38 - 97 NGL View in InterPro
H 38 - 97 NGL View in InterPro
I 38 - 97 NGL View in InterPro
J 38 - 97 NGL View in InterPro
39 - 97 6OSL A 39 - 97 NGL View in InterPro
B 39 - 97 NGL View in InterPro
C 39 - 97 NGL View in InterPro
D 39 - 97 NGL View in InterPro
E 39 - 97 NGL View in InterPro
F 39 - 97 NGL View in InterPro
G 39 - 97 NGL View in InterPro
H 39 - 97 NGL View in InterPro
I 39 - 97 NGL View in InterPro
J 39 - 97 NGL View in InterPro
43 - 83 6CU8 A 43 - 83 NGL View in InterPro
B 43 - 83 NGL View in InterPro
C 43 - 83 NGL View in InterPro
D 43 - 83 NGL View in InterPro
E 43 - 83 NGL View in InterPro
F 43 - 83 NGL View in InterPro
G 43 - 83 NGL View in InterPro
H 43 - 83 NGL View in InterPro
I 43 - 83 NGL View in InterPro
J 43 - 83 NGL View in InterPro
44 - 97 6PES V 44 - 97 NGL View in InterPro
W 44 - 97 NGL View in InterPro
X 44 - 97 NGL View in InterPro
Y 44 - 97 NGL View in InterPro
Z 44 - 97 NGL View in InterPro
45 - 99 6L4S A 45 - 99 NGL View in InterPro
B 45 - 99 NGL View in InterPro
C 45 - 99 NGL View in InterPro
D 45 - 99 NGL View in InterPro
E 45 - 99 NGL View in InterPro
F 45 - 99 NGL View in InterPro
47 - 56 4ZNN A 47 - 56 NGL View in InterPro
48 - 60 6I42 B 48 - 60 NGL View in InterPro
58 - 72 3Q28 A 372 - 386 NGL View in InterPro
68 - 78 4RIL A 68 - 78 NGL View in InterPro
69 - 77 4RIK A 69 - 77 NGL View in InterPro
70 - 76 4R0W A 1 - 7 NGL View in InterPro
72 - 78 4R0U A 1 - 7 NGL View in InterPro
9 - 93 6RTB A 9 - 93 NGL View in InterPro
B 9 - 93 NGL View in InterPro
C 9 - 93 NGL View in InterPro
D 9 - 93 NGL View in InterPro
E 9 - 93 NGL View in InterPro
F 9 - 93 NGL View in InterPro
G 9 - 93 NGL View in InterPro
H 9 - 93 NGL View in InterPro
I 9 - 93 NGL View in InterPro
J 9 - 93 NGL View in InterPro
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