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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: CDN1A_HUMAN (P38936)

Summary

This is the summary of UniProt entry CDN1A_HUMAN (P38936).

Description: Cyclin-dependent kinase inhibitor 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 164 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 9
Pfam CDI 20 68
disorder n/a 76 105
low_complexity n/a 81 96
disorder n/a 113 115
disorder n/a 117 147
disorder n/a 153 154
disorder n/a 162 164

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P38936. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSEPAGDVRQ NPCGSKACRR LFGPVDSEQL SRDCDALMAG CIQEARERWN
50
51
FDFVTETPLE GDFAWERVRG LGLPKLYLPT GPRRGRDELG GGRRPGTSPA
100
101
LLQGTAEEDH VDLSLSCTLV PRSGEQAEGS PGGPGDSQGR KRRQTSMTDF
150
151
YHSKRRLIFS KRKP                                       
164
 

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Checksums:
CRC64:98D1E7C519ADFCA9
MD5:9ce8168c00c3f6d663f866816b83e0b2

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
CDI 20 - 67 6P8H C 20 - 67 NGL View in InterPro
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TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.