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7  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TCPD_HUMAN (P50991)

Summary

This is the summary of UniProt entry TCPD_HUMAN (P50991).

Description: T-complex protein 1 subunit delta
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 539 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 29
low_complexity n/a 10 23
Pfam Cpn60_TCP1 44 539
disorder n/a 55 56
disorder n/a 58 65

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P50991. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPENVAPRSG ATAGAAGGRG KGAYQDRDKP AQIRFSNISA AKAVADAIRT
50
51
SLGPKGMDKM IQDGKGDVTI TNDGATILKQ MQVLHPAARM LVELSKAQDI
100
101
EAGDGTTSVV IIAGSLLDSC TKLLQKGIHP TIISESFQKA LEKGIEILTD
150
151
MSRPVELSDR ETLLNSATTS LNSKVVSQYS SLLSPMSVNA VMKVIDPATA
200
201
TSVDLRDIKI VKKLGGTIDD CELVEGLVLT QKVSNSGITR VEKAKIGLIQ
250
251
FCLSAPKTDM DNQIVVSDYA QMDRVLREER AYILNLVKQI KKTGCNVLLI
300
301
QKSILRDALS DLALHFLNKM KIMVIKDIER EDIEFICKTI GTKPVAHIDQ
350
351
FTADMLGSAE LAEEVNLNGS GKLLKITGCA SPGKTVTIVV RGSNKLVIEE
400
401
AERSIHDALC VIRCLVKKRA LIAGGGAPEI ELALRLTEYS RTLSGMESYC
450
451
VRAFADAMEV IPSTLAENAG LNPISTVTEL RNRHAQGEKT AGINVRKGGI
500
501
SNILEELVVQ PLLVSVSALT LATETVRSIL KIDDVVNTR            
539
 

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Checksums:
CRC64:39913C0D0735180D
MD5:5ef644b2f1183c633820de367714aa69

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Cpn60_TCP1 44 - 533 6NR8 D 44 - 533 NGL View in InterPro
6NR9 D 44 - 533 NGL View in InterPro
6NRA D 44 - 533 NGL View in InterPro
6NRB D 44 - 533 NGL View in InterPro
6NRC D 44 - 533 NGL View in InterPro
6NRD D 44 - 533 NGL View in InterPro
44 - 539 6NR8 L 44 - 539 NGL View in InterPro
6NR9 L 44 - 539 NGL View in InterPro
6NRA L 44 - 539 NGL View in InterPro
6NRB L 44 - 539 NGL View in InterPro
6NRC L 44 - 539 NGL View in InterPro
6NRD L 44 - 539 NGL View in InterPro
6QB8 D 44 - 539 NGL View in InterPro
d 44 - 539 NGL View in InterPro
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The parts of the structure corresponding to the Pfam family are highlighted in yellow.

Loading Structure Data

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;