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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: ARO8_YEAST (P53090)

Summary

This is the summary of UniProt entry ARO8_YEAST (P53090).

Description: Aromatic/aminoadipate aminotransferase 1 EC=2.6.1.39 EC=2.6.1.57
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (NCBI taxonomy ID 559292)
Length: 500 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 63 66
Pfam Aminotran_1_2 97 488
disorder n/a 213 214
disorder n/a 264 268
disorder n/a 270 272
disorder n/a 274 276
disorder n/a 448 457

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P53090. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTLPESKDFS YLFSDETNAR KPSPLKTCIH LFQDPNIIFL GGGLPLKDYF
50
51
PWDNLSVDSP KPPFPQGIGA PIDEQNCIKY TVNKDYADKS ANPSNDIPLS
100
101
RALQYGFSAG QPELLNFIRD HTKIIHDLKY KDWDVLATAG NTNAWESTLR
150
151
VFCNRGDVIL VEAHSFSSSL ASAEAQGVIT FPVPIDADGI IPEKLAKVME
200
201
NWTPGAPKPK LLYTIPTGQN PTGTSIADHR KEAIYKIAQK YDFLIVEDEP
250
251
YYFLQMNPYI KDLKEREKAQ SSPKQDHDEF LKSLANTFLS LDTEGRVIRM
300
301
DSFSKVLAPG TRLGWITGSS KILKPYLSLH EMTIQAPAGF TQVLVNATLS
350
351
RWGQKGYLDW LLGLRHEYTL KRDCAIDALY KYLPQSDAFV INPPIAGMFF
400
401
TVNIDASVHP EFKTKYNSDP YQLEQSLYHK VVERGVLVVP GSWFKSEGET
450
451
EPPQPAESKE VSNPNIIFFR GTYAAVSPEK LTEGLKRLGD TLYEEFGISK
500
501
                                                      
500
 

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Checksums:
CRC64:D0D111640D2C560D
MD5:1510b3ce446cd55f945b31b125695a6d

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Aminotran_1_2 97 - 488 4JE5 A 97 - 488 NGL View in InterPro
B 97 - 488 NGL View in InterPro
C 97 - 488 NGL View in InterPro
D 97 - 488 NGL View in InterPro
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The parts of the structure corresponding to the Pfam family are highlighted in yellow.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;