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46  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PSA6_HUMAN (P60900)

Summary

This is the summary of UniProt entry PSA6_HUMAN (P60900).

Description: Proteasome subunit alpha type-6
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 246 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam Proteasome_A_N 9 31
Pfam Proteasome 32 220

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P60900. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSRGSSAGFD RHITIFSPEG RLYQVEYAFK AINQGGLTSV AVRGKDCAVI
50
51
VTQKKVPDKL LDSSTVTHLF KITENIGCVM TGMTADSRSQ VQRARYEAAN
100
101
WKYKYGYEIP VDMLCKRIAD ISQVYTQNAE MRPLGCCMIL IGIDEEQGPQ
150
151
VYKCDPAGYY CGFKATAAGV KQTESTSFLE KKVKKKFDWT FEQTVETAIT
200
201
CLSTVLSIDF KPSEIEVGVV TVENPKFRIL TEAEIDAHLV ALAERD    
246
 

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Checksums:
CRC64:94D1FD3C0A7CC72A
MD5:4ea47ab354ef0b4c357ce4bbc5592c78

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Proteasome 32 - 220 4R3O A 32 - 220 NGL View in InterPro
O 32 - 220 NGL View in InterPro
4R67 A 32 - 220 NGL View in InterPro
c 32 - 220 NGL View in InterPro
O 32 - 220 NGL View in InterPro
q 32 - 220 NGL View in InterPro
5A0Q A 32 - 220 NGL View in InterPro
O 32 - 220 NGL View in InterPro
5GJQ B 32 - 220 NGL View in InterPro
h 32 - 220 NGL View in InterPro
5GJR B 32 - 220 NGL View in InterPro
h 32 - 220 NGL View in InterPro
5L4G A 32 - 220 NGL View in InterPro
N 32 - 220 NGL View in InterPro
5LE5 G 32 - 220 NGL View in InterPro
U 32 - 220 NGL View in InterPro
5LEX G 32 - 220 NGL View in InterPro
U 32 - 220 NGL View in InterPro
5LEY G 32 - 220 NGL View in InterPro
U 32 - 220 NGL View in InterPro
5LEZ G 32 - 220 NGL View in InterPro
U 32 - 220 NGL View in InterPro
5LF0 G 32 - 220 NGL View in InterPro
U 32 - 220 NGL View in InterPro
5LF1 G 32 - 220 NGL View in InterPro
U 32 - 220 NGL View in InterPro
5LF3 G 32 - 220 NGL View in InterPro
U 32 - 220 NGL View in InterPro
5LF4 G 32 - 220 NGL View in InterPro
U 32 - 220 NGL View in InterPro
5LF6 G 32 - 220 NGL View in InterPro
U 32 - 220 NGL View in InterPro
5LF7 G 32 - 220 NGL View in InterPro
U 32 - 220 NGL View in InterPro
5LN3 A 32 - 220 NGL View in InterPro
5M32 G 32 - 220 NGL View in InterPro
U 32 - 220 NGL View in InterPro
5T0C AG 32 - 220 NGL View in InterPro
BG 32 - 220 NGL View in InterPro
5T0G G 32 - 220 NGL View in InterPro
5T0H G 32 - 220 NGL View in InterPro
5T0I G 32 - 220 NGL View in InterPro
5T0J G 32 - 220 NGL View in InterPro
5VFO g 32 - 220 NGL View in InterPro
G 32 - 220 NGL View in InterPro
5VFP g 32 - 220 NGL View in InterPro
G 32 - 220 NGL View in InterPro
5VFQ g 32 - 220 NGL View in InterPro
G 32 - 220 NGL View in InterPro
5VFR g 32 - 220 NGL View in InterPro
G 32 - 220 NGL View in InterPro
5VFS g 32 - 220 NGL View in InterPro
G 32 - 220 NGL View in InterPro
5VFT g 32 - 220 NGL View in InterPro
G 32 - 220 NGL View in InterPro
5VFU g 32 - 220 NGL View in InterPro
G 32 - 220 NGL View in InterPro
6AVO K 32 - 220 NGL View in InterPro
R 32 - 220 NGL View in InterPro
6E5B G 32 - 220 NGL View in InterPro
U 32 - 220 NGL View in InterPro
6KWY G 32 - 220 NGL View in InterPro
U 32 - 220 NGL View in InterPro
6MSB g 32 - 220 NGL View in InterPro
G 32 - 220 NGL View in InterPro
6MSD g 32 - 220 NGL View in InterPro
G 32 - 220 NGL View in InterPro
6MSE g 32 - 220 NGL View in InterPro
G 32 - 220 NGL View in InterPro
6MSG g 32 - 220 NGL View in InterPro
G 32 - 220 NGL View in InterPro
6MSH g 32 - 220 NGL View in InterPro
G 32 - 220 NGL View in InterPro
6MSJ g 32 - 220 NGL View in InterPro
G 32 - 220 NGL View in InterPro
6MSK g 32 - 220 NGL View in InterPro
G 32 - 220 NGL View in InterPro
6R70 G 32 - 220 NGL View in InterPro
U 32 - 220 NGL View in InterPro
6REY A 32 - 220 NGL View in InterPro
O 32 - 220 NGL View in InterPro
6RGQ A 32 - 220 NGL View in InterPro
O 32 - 220 NGL View in InterPro
6WJD g 32 - 220 NGL View in InterPro
G 32 - 220 NGL View in InterPro
6WJN g 32 - 220 NGL View in InterPro
G 32 - 220 NGL View in InterPro
6XMJ A 32 - 220 NGL View in InterPro
Proteasome_A_N 10 - 31 5A0Q A 10 - 31 NGL View in InterPro
O 10 - 31 NGL View in InterPro
9 - 31 4R3O A 9 - 31 NGL View in InterPro
O 9 - 31 NGL View in InterPro
4R67 A 9 - 31 NGL View in InterPro
c 9 - 31 NGL View in InterPro
O 9 - 31 NGL View in InterPro
q 9 - 31 NGL View in InterPro
5GJQ B 9 - 31 NGL View in InterPro
h 9 - 31 NGL View in InterPro
5GJR B 9 - 31 NGL View in InterPro
h 9 - 31 NGL View in InterPro
5L4G A 9 - 31 NGL View in InterPro
N 9 - 31 NGL View in InterPro
5LE5 G 9 - 31 NGL View in InterPro
U 9 - 31 NGL View in InterPro
5LEX G 9 - 31 NGL View in InterPro
U 9 - 31 NGL View in InterPro
5LEY G 9 - 31 NGL View in InterPro
U 9 - 31 NGL View in InterPro
5LEZ G 9 - 31 NGL View in InterPro
U 9 - 31 NGL View in InterPro
5LF0 G 9 - 31 NGL View in InterPro
U 9 - 31 NGL View in InterPro
5LF1 G 9 - 31 NGL View in InterPro
U 9 - 31 NGL View in InterPro
5LF3 G 9 - 31 NGL View in InterPro
U 9 - 31 NGL View in InterPro
5LF4 G 9 - 31 NGL View in InterPro
U 9 - 31 NGL View in InterPro
5LF6 G 9 - 31 NGL View in InterPro
U 9 - 31 NGL View in InterPro
5LF7 G 9 - 31 NGL View in InterPro
U 9 - 31 NGL View in InterPro
5LN3 A 9 - 31 NGL View in InterPro
5M32 G 9 - 31 NGL View in InterPro
U 9 - 31 NGL View in InterPro
5T0C AG 9 - 31 NGL View in InterPro
BG 9 - 31 NGL View in InterPro
5T0G G 9 - 31 NGL View in InterPro
5T0H G 9 - 31 NGL View in InterPro
5T0I G 9 - 31 NGL View in InterPro
5T0J G 9 - 31 NGL View in InterPro
5VFO g 9 - 31 NGL View in InterPro
G 9 - 31 NGL View in InterPro
5VFP g 9 - 31 NGL View in InterPro
G 9 - 31 NGL View in InterPro
5VFQ g 9 - 31 NGL View in InterPro
G 9 - 31 NGL View in InterPro
5VFR g 9 - 31 NGL View in InterPro
G 9 - 31 NGL View in InterPro
5VFS g 9 - 31 NGL View in InterPro
G 9 - 31 NGL View in InterPro
5VFT g 9 - 31 NGL View in InterPro
G 9 - 31 NGL View in InterPro
5VFU g 9 - 31 NGL View in InterPro
G 9 - 31 NGL View in InterPro
6AVO K 9 - 31 NGL View in InterPro
R 9 - 31 NGL View in InterPro
6E5B G 9 - 31 NGL View in InterPro
U 9 - 31 NGL View in InterPro
6KWY G 9 - 31 NGL View in InterPro
U 9 - 31 NGL View in InterPro
6MSB g 9 - 31 NGL View in InterPro
G 9 - 31 NGL View in InterPro
6MSD g 9 - 31 NGL View in InterPro
G 9 - 31 NGL View in InterPro
6MSE g 9 - 31 NGL View in InterPro
G 9 - 31 NGL View in InterPro
6MSG g 9 - 31 NGL View in InterPro
G 9 - 31 NGL View in InterPro
6MSH g 9 - 31 NGL View in InterPro
G 9 - 31 NGL View in InterPro
6MSJ g 9 - 31 NGL View in InterPro
G 9 - 31 NGL View in InterPro
6MSK g 9 - 31 NGL View in InterPro
G 9 - 31 NGL View in InterPro
6R70 G 9 - 31 NGL View in InterPro
U 9 - 31 NGL View in InterPro
6REY A 9 - 31 NGL View in InterPro
O 9 - 31 NGL View in InterPro
6RGQ A 9 - 31 NGL View in InterPro
O 9 - 31 NGL View in InterPro
6WJD g 9 - 31 NGL View in InterPro
G 9 - 31 NGL View in InterPro
6WJN g 9 - 31 NGL View in InterPro
G 9 - 31 NGL View in InterPro
6XMJ A 9 - 31 NGL View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in yellow.

Loading Structure Data

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;