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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ENK21_HUMAN (P61565)

Summary

This is the summary of UniProt entry ENK21_HUMAN (P61565).

Description: Endogenous retrovirus group K member 21 Env polyprotein
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 698 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 50
low_complexity n/a 8 22
Pfam HERV-K_REC 19 104
disorder n/a 63 64
low_complexity n/a 93 98
Pfam HERV-K_env_2 114 282
disorder n/a 224 228
disorder n/a 285 286
disorder n/a 292 294
disorder n/a 325 327
transmembrane n/a 465 490
low_complexity n/a 478 489
Pfam GP41 485 681
coiled_coil n/a 575 595
transmembrane n/a 632 654
low_complexity n/a 637 656

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P61565. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MHPSEMQRKA PPRRRRHRNR APLTHKMNKM VTSEQMKLPS TKKAEPPTWA
50
51
QLKKLTQLAT KYLENTKVTQ TPESMLLAAL MIVSMVVSLP MPAGAAAANY
100
101
TNWAYVPFPP LIRAVTWMDN PIEVYVNDSV WVHGPIDDRC PAKPEEEGMM
150
151
INISIGYHYP PICLGRAPGC LMPAVQNWLV EVPTVSPISR FTYNMVSGMS
200
201
LRPRVNYLQD FSYQRSLKFR PKGKPCPKEI PKESKNTEVL VWEECVANSV
250
251
VILQNNEFGT IIDWAPRGQF YHNCSGQTQS CPSAQVSPAV DSDLTESLDK
300
301
HKHKKLQSFY PWEWGEKGIS TPRPKIISPV SGPEHPELWR LTVASHHIRI
350
351
WSGNQTLETR DRKPFYTVDL NSSLTVPLQS CVKPPYMLVV GNIVIKPDSQ
400
401
TITCENCRLL TCIDSTFNWQ HRILLVRARE GVWIPVSMDR PWEASPSIHI
450
451
LTEVLKGVLN RSKRFIFTLI AVIMGLIAVT AMAAVAGVAL HSFVQSVNFV
500
501
NDWQKNSTRL WNSQSSIDQK LANQINDLRQ TVIWMGDRLM SLEHRFQLQC
550
551
DWNTSDFCIT PQIYNESEHH WDMVRRHLQG REDNLTLDIS KLKEQIFEAS
600
601
KAHLNLVPGT EAIAGVADGL ANLNPVTWVK TIGSTTIINL ILILVCLFCL
650
651
LLVCRCTQQL RRDSDHRERA MMTMVVLSKR KGGNVGKSKR DQIVTVSV  
698
 

Show the unformatted sequence.

Checksums:
CRC64:367669EE890E465A
MD5:d67b60e6b3eef9b649fb7ab87a3f7bad

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;