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31  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RUXE_HUMAN (P62304)

Summary

This is the summary of UniProt entry RUXE_HUMAN (P62304).

Description: Small nuclear ribonucleoprotein E
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 92 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
low_complexity n/a 5 16
Pfam LSM 23 89

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P62304. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAYRGQGQKV QKVMVQPINL IFRYLQNRSR IQVWLYEQVN MRIEGCIIGF
50
51
DEYMNLVLDD AEEIHSKTKS RKQLGRIMLK GDNITLLQSV SN        
92
 

Show the unformatted sequence.

Checksums:
CRC64:7D8881CE1F4FA2FD
MD5:9b2f92131d7d34356e7f2269768c02ef

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
LSM 23 - 89 3CW1 E 23 - 89 Show 3D Structure View in InterPro
W 223 - 289 Show 3D Structure View in InterPro
X 423 - 489 Show 3D Structure View in InterPro
Y 623 - 689 Show 3D Structure View in InterPro
3JCR S 23 - 89 Show 3D Structure View in InterPro
s 23 - 89 Show 3D Structure View in InterPro
3PGW E 23 - 89 Show 3D Structure View in InterPro
H 23 - 89 Show 3D Structure View in InterPro
4PJO e 23 - 89 Show 3D Structure View in InterPro
E 23 - 89 Show 3D Structure View in InterPro
S 23 - 89 Show 3D Structure View in InterPro
s 23 - 89 Show 3D Structure View in InterPro
4V98 Aa 3009 - 3075 Show 3D Structure View in InterPro
AC 3009 - 3075 Show 3D Structure View in InterPro
Ai 3009 - 3075 Show 3D Structure View in InterPro
AK 3009 - 3075 Show 3D Structure View in InterPro
Aq 3009 - 3075 Show 3D Structure View in InterPro
AS 3009 - 3075 Show 3D Structure View in InterPro
Ay 3009 - 3075 Show 3D Structure View in InterPro
Ba 3009 - 3075 Show 3D Structure View in InterPro
BC 3009 - 3075 Show 3D Structure View in InterPro
Bi 3009 - 3075 Show 3D Structure View in InterPro
BK 3009 - 3075 Show 3D Structure View in InterPro
Bq 3009 - 3075 Show 3D Structure View in InterPro
BS 3009 - 3075 Show 3D Structure View in InterPro
By 3009 - 3075 Show 3D Structure View in InterPro
Ca 3009 - 3075 Show 3D Structure View in InterPro
CC 3009 - 3075 Show 3D Structure View in InterPro
Ci 3009 - 3075 Show 3D Structure View in InterPro
CK 3009 - 3075 Show 3D Structure View in InterPro
Cq 3009 - 3075 Show 3D Structure View in InterPro
CS 3009 - 3075 Show 3D Structure View in InterPro
4WZJ E 23 - 89 Show 3D Structure View in InterPro
EE 23 - 89 Show 3D Structure View in InterPro
EEE 23 - 89 Show 3D Structure View in InterPro
EEEE 23 - 89 Show 3D Structure View in InterPro
L 23 - 89 Show 3D Structure View in InterPro
LL 23 - 89 Show 3D Structure View in InterPro
LLL 23 - 89 Show 3D Structure View in InterPro
LLLL 23 - 89 Show 3D Structure View in InterPro
S 23 - 89 Show 3D Structure View in InterPro
SS 23 - 89 Show 3D Structure View in InterPro
SSS 23 - 89 Show 3D Structure View in InterPro
SSSS 23 - 89 Show 3D Structure View in InterPro
5MQF c 23 - 89 Show 3D Structure View in InterPro
j 23 - 89 Show 3D Structure View in InterPro
5O9Z c 23 - 89 Show 3D Structure View in InterPro
j 23 - 89 Show 3D Structure View in InterPro
U 23 - 89 Show 3D Structure View in InterPro
5XJC e 23 - 89 Show 3D Structure View in InterPro
l 23 - 89 Show 3D Structure View in InterPro
5XJL E 23 - 89 Show 3D Structure View in InterPro
5XJQ E 23 - 89 Show 3D Structure View in InterPro
5XJR E 23 - 89 Show 3D Structure View in InterPro
5XJS E 23 - 89 Show 3D Structure View in InterPro
5XJT E 23 - 89 Show 3D Structure View in InterPro
5XJU E 23 - 89 Show 3D Structure View in InterPro
5YZG e 23 - 89 Show 3D Structure View in InterPro
l 23 - 89 Show 3D Structure View in InterPro
5Z56 e 23 - 89 Show 3D Structure View in InterPro
l 23 - 89 Show 3D Structure View in InterPro
5Z57 e 23 - 89 Show 3D Structure View in InterPro
l 23 - 89 Show 3D Structure View in InterPro
5Z58 e 23 - 89 Show 3D Structure View in InterPro
l 23 - 89 Show 3D Structure View in InterPro
6AH0 c 23 - 89 Show 3D Structure View in InterPro
l 23 - 89 Show 3D Structure View in InterPro
R 23 - 89 Show 3D Structure View in InterPro
6FF7 c 23 - 89 Show 3D Structure View in InterPro
j 23 - 89 Show 3D Structure View in InterPro
6ICZ e 23 - 89 Show 3D Structure View in InterPro
l 23 - 89 Show 3D Structure View in InterPro
6ID0 e 23 - 89 Show 3D Structure View in InterPro
l 23 - 89 Show 3D Structure View in InterPro
6ID1 e 23 - 89 Show 3D Structure View in InterPro
l 23 - 89 Show 3D Structure View in InterPro
6QDV e 23 - 89 Show 3D Structure View in InterPro
p 23 - 89 Show 3D Structure View in InterPro
6QW6 4e 23 - 89 Show 3D Structure View in InterPro
5e 23 - 89 Show 3D Structure View in InterPro
6QX9 1e 23 - 89 Show 3D Structure View in InterPro
2e 23 - 89 Show 3D Structure View in InterPro
4e 23 - 89 Show 3D Structure View in InterPro
5e 23 - 89 Show 3D Structure View in InterPro
6V4X E 23 - 89 Show 3D Structure View in InterPro
6Y53 j 23 - 89 Show 3D Structure View in InterPro
6Y5Q j 23 - 89 Show 3D Structure View in InterPro
7A5P e 23 - 89 Show 3D Structure View in InterPro
j 23 - 89 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;