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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: THIK_ECOLI (P75948)

Summary

This is the summary of UniProt entry THIK_ECOLI (P75948).

Description: Thiamine kinase EC=2.7.1.89
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
Length: 274 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 2
Pfam APH 24 235
disorder n/a 49 50

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P75948. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPFRSNNPIT RDELLSRFFP QYHPVTTFNS GLSGGSFLIE HQGQRFVVRQ
50
51
PHDPDAPQSA FLRQYRALSQ LPACIAPKPH LYLRDWMVVD YLPGAVKTYL
100
101
PDTNELAGLL YYLHQQPRFG WRITLLPLLE LYWQQSDPAR RTVGWLRMLK
150
151
RLRKAREPRP LRLSPLHMDV HAGNLVHSAS GLKLIDWEYA GDGDIALELA
200
201
AVWVENTEQH RQLVNDYATR AKIYPAQLWR QVRRWFPWLL MLKAGWFEYR
250
251
WRQTGDQQFI RLADDTWRQL LIKQ                            
274
 

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Checksums:
CRC64:0F4DBC46F43944CC
MD5:2f1d8892182c2bdc8ee494ff7b806976

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;