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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: LDCA_ECOLI (P76008)

Summary

This is the summary of UniProt entry LDCA_ECOLI (P76008).

Description: Murein tetrapeptide carboxypeptidase EC=3.4.17.13
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
Length: 304 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Peptidase_S66 4 126
Pfam Peptidase_S66C 169 285

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P76008. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSLFHLIAPS GYCIKQHAAL RGIQRLTDAG HQVNNVEVIA RRCERFAGTE
50
51
TERLEDLNSL ARLTTPNTIV LAVRGGYGAS RLLADIDWQA LVARQQHDPL
100
101
LICGHSDFTA IQCGLLAHGN VITFSGPMLV ANFGADELNA FTEHHFWLAL
150
151
RNETFTIEWQ GEGPTCRAEG TLWGGNLAML ISLIGTPWMP KIENGILVLE
200
201
DINEHPFRVE RMLLQLYHAG ILPRQKAIIL GSFSGSTPND YDAGYNLESV
250
251
YAFLRSRLSI PLITGLDFGH EQRTVTLPLG AHAILNNTRE GTQLTISGHP
300
301
VLKM                                                  
304
 

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Checksums:
CRC64:BD801CA75E2AC25F
MD5:a9a7d65ac76c76eca701a94c40bf1a04

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Peptidase_S66 4 - 126 5Z01 A 4 - 126 Show 3D Structure View in InterPro
5Z03 A 4 - 126 Show 3D Structure View in InterPro
B 4 - 126 Show 3D Structure View in InterPro
Peptidase_S66C 169 - 285 5Z01 A 169 - 285 Show 3D Structure View in InterPro
5Z03 A 169 - 285 Show 3D Structure View in InterPro
B 169 - 285 Show 3D Structure View in InterPro
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The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;