Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MTRB_MYCTU (P9WGK9)

Summary

This is the summary of UniProt entry MTRB_MYCTU (P9WGK9).

Description: Sensor histidine kinase MtrB EC=2.7.13.3
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (NCBI taxonomy ID 83332)
Length: 567 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
sig_p n/a 1 62
low_complexity n/a 4 17
disorder n/a 105 106
disorder n/a 142 145
transmembrane n/a 210 233
low_complexity n/a 216 233
Pfam HAMP 232 284
Pfam HisKA 295 362
Pfam HATPase_c 408 519
disorder n/a 479 482
disorder n/a 497 499
disorder n/a 514 515
disorder n/a 521 567
low_complexity n/a 539 551

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P9WGK9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MIFGSRRRIR GRRGRSGPMT RGLSALSRAV AVAWRRSLQL RVVALTLGLS
50
51
LAVILALGFV LTSQVTNRVL DIKVRAAIDQ IERARTTVSG IVNGEETRSL
100
101
DSSLQLARNT LTSKTDPASG AGLAGAFDAV LMVPGDGPRA ASTAGPVDQV
150
151
PNALRGFVKA GQAAYQYATV QTEGFSGPAL IIGTPTLSRV ANLELYLIFP
200
201
LASEQATITL VRGTMATGGL VLLVLLAGIA LLVSRQVVVP VRSASRIAER
250
251
FAEGHLSERM PVRGEDDMAR LAVSFNDMAE SLSRQIAQLE EFGNLQRRFT
300
301
SDVSHELRTP LTTVRMAADL IYDHSADLDP TLRRSTELMV SELDRFETLL
350
351
NDLLEISRHD AGVAELSVEA VDLRTTVNNA LGNVGHLAEE AGIELLVDLP
400
401
AEQVIAEVDA RRVERILRNL IANAIDHAEH KPVRIRMAAD EDTVAVTVRD
450
451
YGVGLRPGEE KLVFSRFWRS DPSRVRRSGG TGLGLAISVE DARLHQGRLE
500
501
AWGEPGEGAC FRLTLPMVRG HKVTTSPLPM KPIPQPVLQP VAQPNPQPMP
550
551
PEYKERQRPR EHAEWSG                                    
567
 

Show the unformatted sequence.

Checksums:
CRC64:B4C73C330DF1764E
MD5:05a846c1c2e9e7d9463e955865fc929a

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;