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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MURF_MYCTU (P9WJL1)

Summary

This is the summary of UniProt entry MURF_MYCTU (P9WJL1).

Description: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase {ECO:0000255|HAMAP-Rule:MF_02019}
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (NCBI taxonomy ID 83332)
Length: 510 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam Mur_ligase 32 118
low_complexity n/a 40 55
low_complexity n/a 61 82
low_complexity n/a 74 97
low_complexity n/a 106 129
low_complexity n/a 130 144
Pfam Mur_ligase_M 134 321
disorder n/a 170 171
Pfam Mur_ligase_C 341 434
disorder n/a 342 346
disorder n/a 348 350
disorder n/a 445 447
disorder n/a 450 451
disorder n/a 453 457
low_complexity n/a 467 477
low_complexity n/a 489 502

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P9WJL1. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MIELTVAQIA EIVGGAVADI SPQDAAHRRV TGTVEFDSRA IGPGGLFLAL
50
51
PGARADGHDH AASAVAAGAA VVLAARPVGV PAIVVPPVAA PNVLAGVLEH
100
101
DNDGSGAAVL AALAKLATAV AAQLVAGGLT IIGITGSSGK TSTKDLMAAV
150
151
LAPLGEVVAP PGSFNNELGH PWTVLRATRR TDYLILEMAA RHHGNIAALA
200
201
EIAPPSIGVV LNVGTAHLGE FGSREVIAQT KAELPQAVPH SGAVVLNADD
250
251
PAVAAMAKLT AARVVRVSRD NTGDVWAGPV SLDELARPRF TLHAHDAQAE
300
301
VRLGVCGDHQ VTNALCAAAV ALECGASVEQ VAAALTAAPP VSRHRMQVTT
350
351
RGDGVTVIDD AYNANPDSMR AGLQALAWIA HQPEATRRSW AVLGEMAELG
400
401
EDAIAEHDRI GRLAVRLDVS RLVVVGTGRS ISAMHHGAVL EGAWGSGEAT
450
451
ADHGADRTAV NVADGDAALA LLRAELRPGD VVLVKASNAA GLGAVADALV
500
501
ADDTCGSVRP                                            
510
 

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Checksums:
CRC64:7BE83EDD1BAA2EC4
MD5:7180778c4210d5ce9703e009f4c26368

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;