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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PPSE_MYCTU (P9WQE1)

Summary

This is the summary of UniProt entry PPSE_MYCTU (P9WQE1).

Description: Phenolphthiocerol/phthiocerol polyketide synthase subunit E {ECO:0000305}
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (NCBI taxonomy ID 83332)
Length: 1488 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam ketoacyl-synt 5 262
Pfam Ketoacyl-synt_C 270 390
disorder n/a 389 391
Pfam KAsynt_C_assoc 392 507
low_complexity n/a 437 453
disorder n/a 438 448
disorder n/a 473 475
disorder n/a 477 480
disorder n/a 489 492
disorder n/a 505 506
disorder n/a 528 542
Pfam Acyl_transf_1 551 868
disorder n/a 694 695
disorder n/a 703 704
disorder n/a 754 755
disorder n/a 762 763
disorder n/a 766 769
disorder n/a 771 773
disorder n/a 818 819
disorder n/a 822 829
disorder n/a 832 843
disorder n/a 899 931
Pfam PP-binding 937 1000
low_complexity n/a 965 976
disorder n/a 1011 1017
disorder n/a 1020 1021
Pfam Condensation 1024 1457
disorder n/a 1098 1103
low_complexity n/a 1128 1145
disorder n/a 1133 1134
disorder n/a 1235 1239
disorder n/a 1242 1245
low_complexity n/a 1284 1297
disorder n/a 1392 1393
disorder n/a 1463 1475
disorder n/a 1482 1483

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P9WQE1. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSIPENAIAV VGMAGRFPGA KDVSAFWSNL RRGKESIVTL SEQELRDAGV
50
51
SDKTLADPAY VRRAPLLDGI DEFDAGFFGF PPLAAQVLDP QHRLFLQCAW
100
101
HALEDAGADP ARFDGSIGVY GTSSPSGYLL HNLLSHRDPN AVLAEGLNFD
150
151
QFSLFLQNDK DFLATRISHA FNLRGPSIAV QTACSSSLVA VHLACLSLLS
200
201
GECDMALAGG SSLCIPHRVG YFTSPGSMVS AVGHCRPFDV RADGTVFGSG
250
251
VGLVVLKPLA AAIDAGDRIH AVIRGSAINN DGSAKMGYAA PNPAAQADVI
300
301
AEAHAVSGID SSTVSYVECH GTGTPLGDPI EIQGLRAAFE VSQTSRSAPC
350
351
VLGSVKSNIG HLEVAAGIAG LIKTILCLKN KALPATLHYT SPNPELRLDQ
400
401
SPFVVQSKYG PWECDGVRRA GVSSFGVGGT NAHVVLEEAP AEASEVSAHA
450
451
EPAGPQVILL SAQTAAALGE SRTALAAALE TQDGPRLSDV AYTLARRRKH
500
501
NVTMAAVVHD REHAATVLRA AEHDNVFVGE AAHDGEHGDR ADAAPTSDRV
550
551
VFLFPGQGAQ HVGMAKGLYD TEPVFAQHFD TCAAGFRDET GIDLHAEVFD
600
601
GTATDLERID RSQPALFTVE YALAKLVDTF GVRAGAYIGY STGEYIAATL
650
651
AGVFDLQTAI KTVSLRARLM HESPPGAMVA VALGPDDVTQ YLPPEVELSA
700
701
VNDPGNCVVA GPKDQIRALR QRLTEAGIPV RRVRATHAFH TSAMDPMLGQ
750
751
FQEFLSRQQL RPPRTPLLSN LTGSWMSDQQ VVDPASWTRQ ISSPIRFADE
800
801
LDVVLAAPSR ILVEVGPGGS LTGSAMRHPK WSTTHRTVRL MRHPLQDVDD
850
851
RDTFLRALGE LWSAGVEVDW TPRRPAVPHL VSLPGYPFAR QRHWVEPNHT
900
901
VWAQAPGANN GSPAGTADGS TAATVDAARN GESQTEVTLQ RIWSQCLGVS
950
951
SVDRNANFFD LGGDSLMAIS IAMAAANEGL TITPQDLYEY PTLASLTAAV
1000
1001
DASFASSGLA KPPEAQANPA VPPNVTYFLD RGLRDTGRCR VPLILRLDPK
1050
1051
IGLPDIRAVL TAVVNHHDAL RLHLVGNDGI WEQHIAAPAE FTGLSNRSVP
1100
1101
NGVAAGSPEE RAAVLGILAE LLEDQTDPNA PLAAVHIAAA HGGPHYLCLA
1150
1151
IHAMVTDDSS RQILATDIVT AFGQRLAGEE ITLEPVSTGW REWSLRCAAL
1200
1201
ATHPAALDTR SYWIENSTKA TLWLADALPN AHTAHPPRAD ELTKLSSTLS
1250
1251
VEQTSELDDG RRRFRRSIQT ILLAALGRTI AQTVGEGVVA VELEGEGRSV
1300
1301
LRPDVDLRRT VGWFTTYYPV PLACATGLGA LAQLDAVHNT LKSVPHYGIG
1350
1351
YGLLRYVYAP TGRVLGAQRT PDIHFRYAGV IPELPSGDAP VQFDSDMTLP
1400
1401
VREPIPGMGH AIELRVYRFG GSLHLDWWYD TRRIPAATAE ALERTFPLAL
1450
1451
SALIQEAIAA EHTEHDDSEI VGEPEAGALV DLSSMDAG             
1488
 

Show the unformatted sequence.

Checksums:
CRC64:C6418D88A27BB701
MD5:8d8a2ee23096fb1e469ffc045e877b3a

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;