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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CREM_HUMAN (Q03060)

Summary

This is the summary of UniProt entry CREM_HUMAN (Q03060).

Description: cAMP-responsive element modulator {ECO:0000305}
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 345 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 46
disorder n/a 50 60
disorder n/a 90 113
Pfam pKID 98 140
disorder n/a 116 120
disorder n/a 125 126
disorder n/a 128 158
low_complexity n/a 139 146
disorder n/a 173 176
disorder n/a 181 212
disorder n/a 223 227
disorder n/a 229 231
disorder n/a 233 255
disorder n/a 266 299
Pfam bZIP_1 284 344
low_complexity n/a 295 309
coiled_coil n/a 311 338

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q03060. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTMETVESQH DGSITASLTE SKSAHVQTQT GQNSIPALAQ VSVAGSGTRR
50
51
GSPAVTLVQL PSGQTIHVQG VIQTPQPWVI QSSEIHTVQV AAIAETDESA
100
101
ESEGVIDSHK RREILSRRPS YRKILNELSS DVPGVPKIEE ERSEEEGTPP
150
151
SIATMAVPTS IYQTSTGQYI AIAQGGTIQI SNPGSDGVQG LQALTMTNSG
200
201
APPPGATIVQ YAAQSADGTQ QFFVPGSQVV VQDEETELAP SHMAAATGDM
250
251
PTYQIRAPTA ALPQGVVMAA SPGSLHSPQQ LAEEATRKRE LRLMKNREAA
300
301
KECRRRKKEY VKCLESRVAV LEVQNKKLIE ELETLKDICS PKTDY     
345
 

Show the unformatted sequence.

Checksums:
CRC64:4DDEE62904CDD0E6
MD5:17e36245fa355521c7d7b74520a70ce4

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;