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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TLE4_RAT (Q07141)

Summary

This is the summary of UniProt entry TLE4_RAT (Q07141).

Description: Transducin-like enhancer protein 4
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 748 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
low_complexity n/a 10 23
disorder n/a 12 14
Pfam TLE_N 24 117
coiled_coil n/a 32 59
low_complexity n/a 102 115
disorder n/a 132 135
low_complexity n/a 138 153
disorder n/a 146 147
disorder n/a 155 339
low_complexity n/a 176 191
low_complexity n/a 201 213
low_complexity n/a 264 282
low_complexity n/a 279 291
disorder n/a 346 349
disorder n/a 352 358
disorder n/a 360 373
low_complexity n/a 380 390
disorder n/a 401 405
disorder n/a 407 414
disorder n/a 439 444
disorder n/a 450 452
Pfam WD40 546 580
Pfam WD40 584 622

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q07141. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MIRDLSKMYR RRAHPAPHQP AQPFKFTISE SCDRIKEEFQ FLQAQYHSLK
50
51
LECEKLASEK TEMQRHYVMY YEMSYGLNIE MHKQAEIVKR LNAICAQVIP
100
101
CLSQEQQQLQ AQHLLTWTWS ACASDTTPLG FSQPFHPSGS SAGLLALSSA
150
151
LGGQSHLPIK DEKKHHDNDH QRDRDSIKSS SVSPSASFRG SEKHRNSTDY
200
201
SSESKKQKTE EKEIAARYDS DGEKSDDNLV VDVSNEDPSS PRGSPAHSPR
250
251
ENGLDKTRLL KKDAPISPAS VASSSSTPSS KSKELSLNEK STTPVSKSNT
300
301
PTPRTDAPTP GSNSTPGLRP VPGKPPGVDP LASSLRTPMA VPCPYPTPFG
350
351
IVPHAGMNGE LTSPGAAYAG LHNISPQMSA AAAAAAAAAA YGRSPVVGFD
400
401
PHHHMRVPAI PPNLTGIPGG KPAYSFHVSA DGQMQPVPFP PDALIGPGIP
450
451
RHARQINTLN HGEVVCAVTI SNPTRHVYTG GKGCVKVWDI TDPGNKSPVS
500
501
QLDCLNRDNY IRSCRLLPDG RTLIVGGEAS TLSIWDLAAP TPRIKAELTS
550
551
SAPACYALAI SPDSKVCFSC CSDGNIAVWD LHNQTLVRQF QGHTDGASCI
600
601
DISNDGTKLW TGGLDNTVRS WDLREGRQLQ QHDFTSQIFS LGYCPTGEWL
650
651
AVGMENSNVE VLHVTKPDKY QLHLHESCVL SLKFAHCGKW FVRPGKDNLL
700
701
NAWRTPYGAS IFQSKESSSV LSCDISADDK YIVTGSGDKK ATVYEVIY  
748
 

Show the unformatted sequence.

Checksums:
CRC64:E6DB66EBAECD66AD
MD5:03865c8c1f8cd27ad668466e8d2b4f6f

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;