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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: GIN4_YEAST (Q12263)

Summary

This is the summary of UniProt entry GIN4_YEAST (Q12263).

Description: Serine/threonine-protein kinase GIN4 EC=2.7.11.1
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (NCBI taxonomy ID 559292)
Length: 1142 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Pkinase 19 289
disorder n/a 253 254
disorder n/a 341 348
low_complexity n/a 373 395
disorder n/a 379 411
low_complexity n/a 419 440
disorder n/a 421 427
disorder n/a 429 447
low_complexity n/a 438 453
disorder n/a 450 492
low_complexity n/a 489 502
disorder n/a 494 511
disorder n/a 514 517
coiled_coil n/a 553 636
low_complexity n/a 557 614
disorder n/a 570 597
disorder n/a 625 628
disorder n/a 630 651
coiled_coil n/a 642 662
disorder n/a 673 704
disorder n/a 743 745
disorder n/a 754 756
disorder n/a 759 764
disorder n/a 767 780
disorder n/a 782 785
disorder n/a 834 883
disorder n/a 891 1023
low_complexity n/a 954 981
disorder n/a 1025 1030
Pfam Fungal_KA1 1026 1141
low_complexity n/a 1029 1040

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q12263. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAINGNSIPA IKDNTIGPWK LGETLGLGST GKVQLARNGS TGQEAAVKVI
50
51
SKAVFNTGNV SGTSIVGSTT PDALPYGIER EIIIMKLLNH PNVLRLYDVW
100
101
ETNTDLYLVL EYAEKGELFN LLVERGPLPE HEAIRFFRQI IIGVSYCHAL
150
151
GIVHRDLKPE NLLLDHKYNI KIADFGMAAL ETEGKLLETS CGSPHYAAPE
200
201
IVSGIPYQGF ASDVWSCGVI LFALLTGRLP FDEEDGNIRT LLLKVQKGEF
250
251
EMPSDDEISR EAQDLIRKIL TVDPERRIKT RDILKHPLLQ KYPSIRDSKS
300
301
IRGLPREDTY LTPLSESNSS IDATILQNLV ILWHGRDPEG IKEKLREPGA
350
351
NAEKTLYALL YRFKCDTQKE LIKQQQVKKR QSISSVSVSP SKKVSTTPQR
400
401
RRNRESLISV TSSRKKPISF NKFTASSASS SNLTTPGSSK RLSKNFSSKK
450
451
KLSTIVNQSS PTPASRNKRA SVINVEKNQK RASIFSTTKK NKRSSRSIKR
500
501
MSLIPSMKRE SVTTKLMSTY AKLAEDDDWE YIEKETKRTS SNFATLIDEI
550
551
FEYEKYEQIR KEKEELERKV REAKAREELE RRRRKQEEKE RARKLLEKED
600
601
LKRKQEELKK QIEIDISDLE QELSKHKEEK LDGNIRSISA PMENEEKNIN
650
651
HLEVDIDNIL RRRNFSLQTR PVSRLDPGIM FSSPTEEVSP VEPKRTENER
700
701
LTTEKKILET IRRSKFLGSS FNIDKELKLS KMEYPSIIAP QRLSEERVVS
750
751
DSNDGYESLI LPKDGNGVSQ LKDSTATTAP VSDGRLRKIS EIRVPQFTRK
800
801
SRHFSESNKR LSVLSMYSTK ESFTNLVDIL KNGNLDVNNQ QSQRIPTPRS
850
851
ADDSEFLFET VNEEAEYTGN SSNDERLYDV GDSTIKDKSA LKLNFADRFN
900
901
GSNEAKQTDN LHLPILPPLN GDNELRKQNS QEGDQAHPKI KSMIPESGSS
950
951
SHTEKEEENE EKEEKKPEQH KQEEDQEKRE KVVDDMEPPL NKSVQKIREK
1000
1001
NAGSQAKDHS KDHLKEHKQD KNTAIGNGSF FRKFSKSSDK TMELYAKISA
1050
1051
KQLFNGLEKL LRGWTQYGLK NIKSHPNNLT LTGKLSSDNI FSLRSTLFEV
1100
1101
NIYPRGKMSV VQFKKVSGSF KAVKKLVNEV ENVLNKEGVL QK        
1142
 

Show the unformatted sequence.

Checksums:
CRC64:EC16FF4BB49DD811
MD5:69654ac165542e07fa154a45ddb73573

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;