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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ZIC1_HUMAN (Q15915)

Summary

This is the summary of UniProt entry ZIC1_HUMAN (Q15915).

Description: Zinc finger protein ZIC 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 447 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 51 52
disorder n/a 58 61
low_complexity n/a 68 85
disorder n/a 75 77
disorder n/a 87 89
low_complexity n/a 110 125
low_complexity n/a 118 134
disorder n/a 139 142
disorder n/a 145 146
disorder n/a 153 155
disorder n/a 157 159
disorder n/a 165 166
disorder n/a 174 185
disorder n/a 189 190
disorder n/a 192 193
Pfam zf_ZIC 218 264
disorder n/a 240 241
low_complexity n/a 250 261
disorder n/a 257 259
Pfam zf-C2H2 302 326
disorder n/a 320 322
Pfam zf-C2H2 332 356
disorder n/a 347 352
disorder n/a 354 355
Pfam zf-C2H2 362 384
disorder n/a 377 434
low_complexity n/a 386 400
low_complexity n/a 403 414
low_complexity n/a 411 427

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q15915. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLLDAGPQYP AIGVTTFGAS RHHSAGDVAE RDVGLGINPF ADGMGAFKLN
50
51
PSSHELASAG QTAFTSQAPG YAAAAALGHH HHPGHVGSYS SAAFNSTRDF
100
101
LFRNRGFGDA AAAASAQHSL FAASAGGFGG PHGHTDAAGH LLFPGLHEQA
150
151
AGHASPNVVN GQMRLGFSGD MYPRPEQYGQ VTSPRSEHYA APQLHGYGPM
200
201
NVNMAAHHGA GAFFRYMRQP IKQELICKWI EPEQLANPKK SCNKTFSTMH
250
251
ELVTHVTVEH VGGPEQSNHI CFWEECPREG KPFKAKYKLV NHIRVHTGEK
300
301
PFPCPFPGCG KVFARSENLK IHKRTHTGEK PFKCEFEGCD RRFANSSDRK
350
351
KHMHVHTSDK PYLCKMCDKS YTHPSSLRKH MKVHESSSQG SQPSPAASSG
400
401
YESSTPPTIV SPSTDNPTTS SLSPSSSAVH HTAGHSALSS NFNEWYV   
447
 

Show the unformatted sequence.

Checksums:
CRC64:4DA3E32C99BF1AAE
MD5:f8b157fd57d1eae81a31e637614fc74c

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;