Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
23  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MAR1_HUMAN (Q16655)

Summary

This is the summary of UniProt entry MAR1_HUMAN (Q16655).

Description: Melanoma antigen recognized by T-cells 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 118 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam MLANA 2 118
transmembrane n/a 27 48
low_complexity n/a 29 44
disorder n/a 90 92
disorder n/a 103 118

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q16655. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPREDAHFIY GYPKKGHGHS YTTAEEAAGI GILTVILGVL LLIGCWYCRR
50
51
RNGYRALMDK SLHVGTQCAL TRRCPQEGFD HRDSKVSLQE KNCEPVVPNA
100
101
PPAYEKLSAE QSPPPYSP                                   
118
 

Show the unformatted sequence.

Checksums:
CRC64:B755BFF39CFCB16E
MD5:73469f9eb1d05f02f220b84464227dc9

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
MLANA 100 - 114 3L6F C 1 - 15 NGL View in InterPro
26 - 35 3HG1 C 1 - 10 NGL View in InterPro
3MRO P 1 - 10 NGL View in InterPro
3MRP P 1 - 10 NGL View in InterPro
3MRQ P 1 - 10 NGL View in InterPro
3QDM C 1 - 10 NGL View in InterPro
4JFF C 1 - 10 NGL View in InterPro
4L3E C 1 - 10 NGL View in InterPro
4QOK C 1 - 10 NGL View in InterPro
5E9D C 1 - 10 NGL View in InterPro
H 1 - 10 NGL View in InterPro
5NHT P 1 - 10 NGL View in InterPro
5NQK P 1 - 10 NGL View in InterPro
6DKP C 1 - 10 NGL View in InterPro
6TMO C 1 - 10 NGL View in InterPro
27 - 35 2GT9 C 1 - 9 NGL View in InterPro
F 1 - 9 NGL View in InterPro
2GTW C 1 - 9 NGL View in InterPro
F 1 - 9 NGL View in InterPro
2GTZ C 1 - 9 NGL View in InterPro
F 1 - 9 NGL View in InterPro
2GUO C 1 - 9 NGL View in InterPro
F 1 - 9 NGL View in InterPro
3QEQ C 1 - 9 NGL View in InterPro
3QFD C 1 - 9 NGL View in InterPro
F 1 - 9 NGL View in InterPro
4EUP C 1 - 9 NGL View in InterPro
F 1 - 9 NGL View in InterPro
4WJ5 C 1 - 9 NGL View in InterPro
F 1 - 9 NGL View in InterPro
6D78 C 2 - 10 NGL View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in yellow.

Loading Structure Data

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;