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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: Q18566_CAEEL (Q18566)

Summary

This is the summary of UniProt entry Q18566_CAEEL (Q18566).

Description: DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279}
Source organism: Caenorhabditis elegans (NCBI taxonomy ID 6239)
Length: 1400 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam RNA_pol_Rpb1_1 12 352
low_complexity n/a 64 78
disorder n/a 233 234
disorder n/a 244 246
disorder n/a 327 340
Pfam RNA_pol_Rpb1_2 354 521
disorder n/a 415 416
disorder n/a 441 443
Pfam RNA_pol_Rpb1_3 524 699
low_complexity n/a 578 588
Pfam RNA_pol_Rpb1_4 724 830
disorder n/a 805 817
Pfam RNA_pol_Rpb1_5 837 1330
disorder n/a 979 980

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q18566. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGKEQFREAD KALKVVGVKF APGDCEFMRQ TAHVPIFNNK LYEDVEGKLQ
50
51
PANYGPLDPK MGVSTKTGTC STCGLGLTDC VGHFGYFDLD VPVFHIGFFK
100
101
LTIQLLQCIC KNCSSILLTP EQHRVFSRQV MNPNLDYLHR KALHKRIVAA
150
151
CKKGSTCSHC GLKNGTVKKA VGAVLKIAFA SPVSVDELGK FATMFSSNQE
200
201
VGDHVRKMKF TLLNPLFVQK LFSNIKEGDI PVLMVRSGEE KHPNDLLLTR
250
251
MPVPPVCIRP SVVSEVKAGT TEDDVTMKLM EIMLTNDVLK KHKRDGAPSK
300
301
TLFETWEHLQ IQCALYINSE MSGLPPDMQP KRAMRAFTQR LKGKQGRFRG
350
351
NLCGKRVDFS GRTVISPDPN LRIDQVGVPI HVAMTLTFPE IVNASNIEKM
400
401
RQLVINGSDV HPGANYLVEK KTGNKKLLKY GKRDELAKNL RMGDTIERHL
450
451
DDNDVVLFNR QPSLHKISIM SHRAKVMPGR TFRFNECACT PYNADFDGDE
500
501
MNLHLPQTYE AKAEASELMN VKNNLITPRS GEPLVAAIQD FITGGYLLTH
550
551
KDTFLPRAEV YRFAAALIDA SAKKQTKIRI PPPAIRRPVE LWTGKQLIEL
600
601
IIRPDKGSDV SLNLTAKNKS YTGNLELCSK DSYVIIRNSV LLAGCLDKSL
650
651
LGSSSKVNIF YMLMRDYGED AAVDAMWRLA RMAPVFLSNR GFSIGIGDVR
700
701
PSEQLLREKG QLVDNGYSKC SQYIKELEEG KLKAQPGCTE EETLESIILR
750
751
ELSTIRDHAG QVCLRNLSKY NAPLTMAVCG SKGSFINISQ MIACVGQQAI
800
801
SGHRPPDGFE ERSLPHFERK KKTPEAKGFV ANSFYSGLTP TEFFFHTMGG
850
851
REGLVDTAVK TAETGYMQRR LVKCLEDLCA SYDGTVRSSV GDVIEFVFGE
900
901
DGLDPAMMEA KDGSVVDFTH VLEHAKNIQT TKEQPIPVDK LDEVLKAEIQ
950
951
KKFKGKYVHF ADKLSEYITQ TEIKKSKKWQ NGKAHCGNHE TADLKTKESC
1000
1001
KICKNLEAYK TSLLANSCLT KTQLCSFIEL CYYKVARAIT EPGTAVGAIA
1050
1051
ATSIGEPSTQ MTLKTFHFAG VASMNITQGV PRIKEIINAV KTISTPIITA
1100
1101
ALLDPYDESL ARRVKARIEK TTLGEICDYI EEVYLPDDYF LLVKLNSKRI
1150
1151
RLLQLEVCME SISYAIATSK VCPQMRGCKI VAHGKTMMAI RPPSTSKLSK
1200
1201
TMTMQILKYS LANVVVKGIP SVNRCVIHAD EKKGDFYSLL VEGTDFRSVL
1250
1251
SSVGVDPRKT NFNNALVVAD VLGIEAARSC IINEIIATMD AHGIGLDRRH
1300
1301
VMLLADVMTY RGEVLGITRN GLVKMKDSVL LLASFEKTMD HLFEAAFFSQ
1350
1351
RDVIHGVSEC IIMGTPMTVG TGTFKLMQKY DKKAVLKQNS PIFERLNVTL
1400
1401
                                                      
1400
 

Show the unformatted sequence.

Checksums:
CRC64:E19CDEE98C4CD8A6
MD5:e4627f7f532936542227cdd4b3d634a7

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;